Dao H, Liu H, Mashtalir N, Kadoch C, Muir T. Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process. J Am Chem Soc. 2022;144(5):2284–2291. PMCID: PMC8935522

Jimah J, Salinas N, Sala-Rabanal M, Jones N, Sibley D, Nichols C, Schlesinger P, Tolia N. Malaria parasite CelTOS targets the inner leaflet of cell membranes for pore-dependent disruption. Elife. 2016;5. PMCID: PMC5132341

Jimah J, Hinshaw J. Structural Insights into the Mechanism of Dynamin Superfamily Proteins. Trends Cell Biol. 2019;29(3):257–273. PMCID: PMC9623552

Song H, Burton A, Shirran S, Fahrig-Kamarauskaitė J, Kaspar H, Muir T, Künzler M, Naismith J. Engineering of a Peptide α-N-Methyltransferase to Methylate Non-Proteinogenic Amino Acids. Angew Chem Int Ed Engl. 2021;60(26):14319–14323. PMCID: PMC8251615

Gao S, Yao X, Yan N. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021;596(7870):143–147. PMCID: PMC8529174

Velthuis A, Grimes J, Fodor E. Structural insights into RNA polymerases of negative-sense RNA viruses. Nat Rev Microbiol. 2021;19(5):303–318. PMCID: PMC7832423

Yan R, Cao P, Song W, Li Y, Wang T, Qian H, Yan C, Yan N. Structural basis for sterol sensing by Scap and Insig. Cell Rep. 2021;35(13):109299. PMID: 34192549

Li Z, Jin X, Wu T, Zhao X, Wang W, Lei J, Pan X, Yan N. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980460

Pan X, Li Z, Jin X, Zhao Y, Huang G, Huang X, Shen Z, Cao Y, Dong M, Lei J, Yan N. Comparative structural analysis of human Na1.1 and Na1.5 reveals mutational hotspots for sodium channelopathies. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980448

Huang J, Yuan Y, Zhao N, Pu D, Tang Q, Zhang S, Luo S, Yang X, Wang N, Xiao Y, Zhang T, Liu Z, Sakata-Kato T, Jiang X, Kato N, Yan N, Yin H. Orthosteric-allosteric dual inhibitors of PfHT1 as selective antimalarial agents. Proc Natl Acad Sci U S A. 2021;118(3). PMCID: PMC7826358

Leicher R, Ge E, Lin X, Reynolds M, Xie W, Walz T, Zhang B, Muir T, Liu S. Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Proc Natl Acad Sci U S A. 2020;117(48):30465–30475. PMCID: PMC7720148

Eisemann T, Allen F, Lau K, Shimamura G, Jeffrey P, Hughson F. The Sec1/Munc18 protein Vps45 holds the Qa-SNARE Tlg2 in an open conformation. Elife. 2020;9. PMCID: PMC7470827

McBride M, Mashtalir N, Winter E, Dao H, Filipovski M, D’Avino A, Seo H-S, Umbreit N, St Pierre R, Valencia A, Qian K, Zullow H, Jaffe J, Dhe-Paganon S, Muir T, Kadoch C. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2020;27(9):836–845. PMCID: PMC7714695

Yao X, Fan X, Yan N. Cryo-EM analysis of a membrane protein embedded in the liposome. Proc Natl Acad Sci U S A. 2020;117(31):18497–18503. PMCID: PMC7414195

Gao S, Valinsky W, On N, Houlihan P, Qu Q, Liu L, Pan X, Clapham D, Yan N. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proc Natl Acad Sci U S A. 2020;117(25):14187–14193. PMCID: PMC7322032

Betsinger C, Cristea I. Mitochondrial Function, Metabolic Regulation, and Human Disease Viewed through the Prism of Sirtuin 4 (SIRT4) Functions. J Proteome Res. 2019;18(5):1929–1938. PMCID: PMC6889813

Cheung-Lee W, Cao L, Link J. Pandonodin: A Proteobacterial Lasso Peptide with an Exceptionally Long C-Terminal Tail. ACS Chem Biol. 2019;14(12):2783–2792. PMCID: PMC7010350

Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N. Cryo-EM structures of apo and antagonist-bound human Ca3.1. Nature. 2019;576(7787):492–497. PMCID: 18083096

Brown A, Chua N, Yan N. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019;10(1):888. PMCID: PMC6384927

Chitrakar A, Rath S, Donovan J, Demarest K, Li Y, Sridhar R, Weiss S, Kotenko S, Wingreen N, Korennykh A. Real-time 2-5A kinetics suggest that interferons β and λ evade global arrest of translation by RNase L. Proc Natl Acad Sci U S A. 2019;116(6):2103–2111. PMCID: PMC6369740

Xie Q, Zhao A, Jeffrey P, Kim M, Bassler B, Stone H, Novick R, Muir T. Identification of a Molecular Latch that Regulates Staphylococcal Virulence. Cell Chem Biol. 2019;26(4):548–558.e4. PMCID: PMC6506218

Carabetta V, Greco T, Cristea I, Dubnau D. YfmK is an N-lysine acetyltransferase that directly acetylates the histone-like protein HBsu in . Proc Natl Acad Sci U S A. 2019;116(9):3752–3757. PMCID: PMC6397556

Cheung-Lee W, Parry M, Cartagena A, Darst S, Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019;294(17):6822–6830. PMCID: PMC6497930

Shen H, Liu D, Wu K, Lei J, Yan N. Structures of human Na1.7 channel in complex with auxiliary subunits and animal toxins. Science. 2019;363(6433):1303–1308. PMID: 30765606

Pan X, Li Z, Huang X, Huang G, Gao S, Shen H, Liu L, Lei J, Yan N. Molecular basis for pore blockade of human Na channel Na1.2 by the μ-conotoxin KIIIA. Science. 2019;363(6433):1309–1313. PMID: 30765605

Zhang J, Mao W, Ren Y, Sun R-N, Yan N, Gong H. Simulating the ion permeation and ion selection for a eukaryotic voltage-gated sodium channel NaPaS. Protein Cell. 2018;9(6):580–585. PMCID: PMC5966359

Braffman N, Piscotta F, Hauver J, Campbell E, Link J, Darst S. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc Natl Acad Sci U S A. 2019;116(4):1273–1278. PMCID: PMC6347699

Song J-G, King M, Zhang R, Kadzik R, Thawani A, Petry S. Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules. J Cell Biol. 2018;217(7):2417–2428. PMCID: PMC6028527

Shi H, Bratton B, Gitai Z, Huang K. How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. Cell. 2018;172(6):1294–1305. PMCID: PMC5846203

Schramma K, Forneris C, Caruso A, Seyedsayamdost M. Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 2018;57(4):461–468. PMID: 29320164

Carey J. Globularity and protein function. J Biomol Struct Dyn. 2000;17 Suppl 1:87–8. PMID: 22607410

Lee J, Sutterlin H, Wzorek J, Mandler M, Hagan C, Grabowicz M, Tomasek D, May M, Hart E, Silhavy T, Kahne D. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018;115(10):2359–2364. PMCID: PMC5877925

Hecht M, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018;48:124–132. PMID: 29306103

Yan N. A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters. J Mol Biol. 2017;429(17):2710–2725. PMID: 28756087

Deng D, Yan N. Crystallization and Structural Determination of the Human Glucose Transporters GLUT1 and GLUT3. Methods Mol Biol. 2018;1713:15–29. PMID: 29218514

Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N. Structure of a fucose transporter in an outward-open conformation. Nature. 2010;467(7316):734–8. PMID: 20877283

Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu J-K, Shi Y, Yan N. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012;335(6069):720–3. PMCID: PMC3586824

Zhang X, Ren W, DeCaen P, Yan C, Tao X, Tang L, Wang J, Hasegawa K, Kumasaka T, He J, Wang J, Clapham D, Yan N. Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature. 2012;486(7401):130–4. PMCID: PMC3979295

Sugihara J, Sun L, Yan N, Kaback R. Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy. Proc Natl Acad Sci U S A. 2012;109(37):14847–51. PMCID: PMC3443143

Sun L, Zeng X, Yan C, Sun X, Gong X, Rao Y, Yan N. Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature. 2012;490(7420):361–6. PMID: 23075985

Yan N. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem Sci. 2013;38(3):151–9. PMID: 23403214

Madej G, Dang S, Yan N, Kaback R. Evolutionary mix-and-match with MFS transporters. Proc Natl Acad Sci U S A. 2013;110(15):5870–4. PMCID: PMC3625355

Xia M, Liu H, Li Y, Yan N, Gong H. The mechanism of Na⁺/K⁺ selectivity in mammalian voltage-gated sodium channels based on molecular dynamics simulation. Biophys J. 2013;104(11):2401–9. PMCID: PMC3672897

Madej G, Sun L, Yan N, Kaback R. Functional architecture of MFS D-glucose transporters. Proc Natl Acad Sci U S A. 2014;111(7):E719–27. PMCID: PMC3932877

Wang J, Yan C, Li Y, Hirata K, Yamamoto M, Yan N, Hu Q. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014;24(12):1486–9. PMCID: PMC4260346

Gong X, Li J, Shao W, Wu J, Qian H, Ren R, Espenshade P, Yan N. Structure of the WD40 domain of SCAP from fission yeast reveals the molecular basis for SREBP recognition. Cell Res. 2015;25(4):401–11. PMCID: PMC4387560

Deng D, Yan N. GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters. Protein Sci. 2016;25(3):546–58. PMCID: PMC4815417

Deng D, Sun P, Yan C, Ke M, Jiang X, Xiong L, Ren W, Hirata K, Yamamoto M, Fan S, Yan N. Molecular basis of ligand recognition and transport by glucose transporters. Nature. 2015;526(7573):391–6. PMID: 26176916

Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, Pardon E, Steyaert J, Yan N, Kaback R. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016;113(44):12420–12425. PMCID: PMC5098631

Ke M, Yuan Y, Jiang X, Yan N, Gong H. Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE. PLoS Comput Biol. 2017;13(6):e1005603. PMCID: PMC5491310