1.Bartman C, Weilandt D, Shen Y, Lee W, Han Y, TeSlaa T, Jankowski C, Samarah L, Park N, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Heiden M, Herranz D, Guo J, Kang Y, Rabinowitz J. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. 2023;614(7947):349–357. PMID: 36725930 Reference Link
1.Zhang Y, Xu Y, Lu W, Li J, Yu S, Brown E, Stanger B, Rabinowitz J, Yang X. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Sci Adv. 2022;8(29):eabo0404. PMCID: PMC9299539 Reference Link
1.Yang L, TeSlaa T, Ng S, Nofal M, Wang L, Lan T, Zeng X, Cowan A, McBride M, Lu W, Davidson S, Liang G, Oh T, Downes M, Evans R, Von Hoff D, Guo J, Han H, Rabinowitz J. Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth. Med. 2022;3(2):119–136. PMCID: PMC9004683 Reference Link
1.Nofal M, Wang T, Yang L, Jankowski C, Li S, Han S, Parsons L, Frese A, Gitai Z, Anthony T, Wühr M, Sabatini D, Rabinowitz J. GCN2 adapts protein synthesis to scavenging-dependent growth. Cell Syst. 2022;13(2):158–172.e9. PMCID: PMC8961722 Reference Link
1.Lee E, Kang Y. Lineage tracing reveals metastatic dynamics. Cancer Cell. 2021;39(8):1050–1052. PMID: 34171265 Reference Link
1.Phan T, Nguyen V, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar M, Gil Z, Diamond D, Rabinowitz J, Rosen S, Melstrom L. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int J Biol Sci. 2021;17(9):2240–2251. PMCID: PMC8241727 Reference Link
1.Schild T, McReynolds M, Shea C, Low V, Schaffer B, Asara J, Piskounova E, Dephoure N, Rabinowitz J, Gomes A, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021;35(11):109238. PMID: 34133937 Reference Link
1.Wong C, Tang L, Davidson C, Vosburgh E, Chen W, Foran D, Notterman D, Levine A, Xu E. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death Differ. 2020;27(1):269–283. PMCID: PMC7206057 Reference Link
1.Hui S, Ghergurovich J, Morscher R, Jang C, Teng X, Lu W, Esparza L, Reya T, Guo J, White E, Rabinowitz J. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017;551(7678):115–118. PMCID: PMC5898814 Reference Link
1.Rajeshkumar N, Yabuuchi S, Pai S, De Oliveira E, Kamphorst J, Rabinowitz J, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang C. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017;23(18):5639–5647. PMCID: PMC6540110 Reference Link
1.Davidson S, Jonas O, Keibler M, Hou H, Luengo A, Mayers J, Wyckoff J, Del Rosario A, Whitman M, Chin C, Condon K, Lammers A, Kellersberger K, Stall B, Stephanopoulos G, Bar-Sagi D, Han J, Rabinowitz J, Cima M, Langer R, Heiden M. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017;23(2):235–241. PMCID: PMC5407288 Reference Link