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NADP

  • 1.
    Jankowski C, Rabinowitz J. Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate. Cancer Res. 2022;82(19):3486–3498. PMCID: PMC9532358
    Reference Link
  • 1.
    Zhang Y, Xu Y, Lu W, Li J, Yu S, Brown E, Stanger B, Rabinowitz J, Yang X. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Sci Adv. 2022;8(29):eabo0404. PMCID: PMC9299539
    Reference Link
  • 1.
    Du J, Estrella M, Solorio-Kirpichyan K, Jeffrey P, Korennykh A. Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc Natl Acad Sci U S A. 2022;119(26):e2200923119. PMCID: PMC9245612
    Reference Link
  • 1.
    Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz G, Clasquin M, Rabinowitz J. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021;3(12):1608–1620. PMCID: PMC8721747
    Reference Link
  • 1.
    Schild T, McReynolds M, Shea C, Low V, Schaffer B, Asara J, Piskounova E, Dephoure N, Rabinowitz J, Gomes A, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021;35(11):109238. PMID: 34133937
    Reference Link
  • 1.
    Ghergurovich J, García-Cañaveras J, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt E, Piqueras-Nebot M, Gomez-Cabrera M, Lahoz A, Fan J, Beier U, Kim H, Rabinowitz J. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020;16(7):731–739. PMCID: PMC7311271
    Reference Link
  • 1.
    Chen L, Zhang Z, Hoshino A, Zheng H, Morley M, Arany Z, Rabinowitz J. NADPH production by the oxidative pentose-phosphate pathway supports folate metabolism. Nat Metab. 2019;1:404–415. PMCID: PMC6489125
    Reference Link
  • 1.
    Zhang Z, Chen L, Liu L, Su X, Rabinowitz J. Chemical Basis for Deuterium Labeling of Fat and NADPH. J Am Chem Soc. 2017;139(41):14368–14371. PMCID: PMC5748894
    Reference Link
  • 1.
    Lu W, Wang L, Chen L, Hui S, Rabinowitz J. Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors. Antioxid Redox Signal. 2018;28(3):167–179. PMCID: PMC5737638
    Reference Link
  • 1.
    Lu W, Su X, Klein M, Lewis I, Fiehn O, Rabinowitz J. Metabolite Measurement: Pitfalls to Avoid and Practices to Follow. Annu Rev Biochem. 2017;86:277–304. PMCID: PMC5734093
    Reference Link
  • 1.
    Ducker G, Chen L, Morscher R, Ghergurovich J, Esposito M, Teng X, Kang Y, Rabinowitz J. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016;23(6):1140–1153. PMCID: PMC4909566
    Reference Link
  • 1.
    Gowers G-O, Robinson J, Brynildsen M. Starved Escherichia coli preserve reducing power under nitric oxide stress. Biochem Biophys Res Commun. 2016;476(1):29–34. PMID: 27207837
    Reference Link
  • 1.
    Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12(5):345–52. PMCID: PMC4891982
    Reference Link

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