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Molecular Structure

  • 1.
    Park J-D, Li Y, Moon K, Han E, Lee S, Seyedsayamdost M. Structural Elucidation of Cryptic Algaecides in Marine Algal-Bacterial Symbioses by NMR Spectroscopy and MicroED. Angew Chem Int Ed Engl. 2022;61(4):e202114022. PMCID: PMC9056321
    Reference Link
  • 1.
    Bushin L, Covington B, Rued B, Federle M, Seyedsayamdost M. Discovery and Biosynthesis of Streptosactin, a Sactipeptide with an Alternative Topology Encoded by Commensal Bacteria in the Human Microbiome. J Am Chem Soc. 2020;142(38):16265–16275. PMID: 32845143
    Reference Link
  • 1.
    He S, Chou H-T, Matthies D, Wunder T, Meyer M, Atkinson N, Martinez-Sanchez A, Jeffrey P, Port S, Patena W, He G, Chen V, Hughson F, McCormick A, Mueller-Cajar O, Engel B, Yu Z, Jonikas M. The structural basis of Rubisco phase separation in the pyrenoid. Nat Plants. 2020;6(12):1480–1490. PMCID: PMC7736253
    Reference Link
  • 1.
    Zhang C, Seyedsayamdost M. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020;59(51):23005–23009. PMID: 32790054
    Reference Link
  • 1.
    Stadlmeier M, Runtsch L, Streshnev F, Wühr M, Carell T. A Click-Chemistry-Based Enrichable Crosslinker for Structural and Protein Interaction Analysis by Mass Spectrometry. Chembiochem. 2020;21(1-2):103–107. PMCID: PMC6980279
    Reference Link
  • 1.
    Greenberg P, Chandler J, Seyedsayamdost M. The Chemistry and Biology of Bactobolin: A 10-Year Collaboration with Natural Product Chemist Extraordinaire Jon Clardy. J Nat Prod. 2020;83(3):738–743. PMCID: PMC8118907
    Reference Link
  • 1.
    Valastyan J, Tota M, Taylor I, Stergioula V, Hone G, Smith C, Henke B, Carson K, Bassler B. Discovery of PqsE Thioesterase Inhibitors for Using DNA-Encoded Small Molecule Library Screening. ACS Chem Biol. 2020;15(2):446–456. PMCID: PMC7036018
    Reference Link
  • 1.
    Paczkowski J, McCready A, Cong J-P, Li Z, Jeffrey P, Smith C, Henke B, Hughson F, Bassler B. An Autoinducer Analogue Reveals an Alternative Mode of Ligand Binding for the LasR Quorum-Sensing Receptor. ACS Chem Biol. 2019;14(3):378–389. PMCID: PMC6601336
    Reference Link
  • 1.
    Tianero M, Balaich J, Donia M. Localized production of defence chemicals by intracellular symbionts of Haliclona sponges. Nat Microbiol. 2019;4(7):1149–1159. PMCID: PMC8647704
    Reference Link
  • 1.
    Okada B, Li A, Seyedsayamdost M. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019;20(15):2005–2011. PMCID: PMC6814388
    Reference Link
  • 1.
    McRose D, Seyedsayamdost M, Morel F. Multiple siderophores: bug or feature?. J Biol Inorg Chem. 2018;23(7):983–993. PMID: 30264174
    Reference Link
  • 1.
    Elashal H, Cohen R, Elashal H, Zong C, Link J, Raj M. Cyclic and Lasso Peptides: Sequence Determination, Topology Analysis, and Rotaxane Formation. Angew Chem Int Ed Engl. 2018;57(21):6150–6154. PMCID: PMC6080247
    Reference Link
  • 1.
    Wang R, Seyedsayamdost M. Roseochelin B, an Algaecidal Natural Product Synthesized by the Roseobacter Phaeobacter inhibens in Response to Algal Sinapic Acid. Org Lett. 2017;19(19):5138–5141. PMID: 28920692
    Reference Link
  • 1.
    Wu Y, Seyedsayamdost M. Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis. Cell Chem Biol. 2017;24(12):1437–1444.e3. PMCID: PMC5741510
    Reference Link
  • 1.
    Baars O, Zhang X, Gibson M, Stone A, Morel F, Seyedsayamdost M. Crochelins: Siderophores with an Unprecedented Iron-Chelating Moiety from the Nitrogen-Fixing Bacterium Azotobacter chroococcum. Angew Chem Int Ed Engl. 2018;57(2):536–541. PMID: 29134779
    Reference Link
  • 1.
    Remillard D, Buckley D, Paulk J, Brien G, Sonnett M, Seo H-S, Dastjerdi S, Wühr M, Dhe-Paganon S, Armstrong S, Bradner J. Degradation of the BAF Complex Factor BRD9 by Heterobifunctional Ligands. Angew Chem Int Ed Engl. 2017;56(21):5738–5743. PMCID: PMC5967236
    Reference Link
  • 1.
    Ducker G, Ghergurovich J, Mainolfi N, Suri V, Jeong S, Li S, Friedman A, Manfredi M, Gitai Z, Kim H, Rabinowitz J. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017;114(43):11404–11409. PMCID: PMC5664509
    Reference Link
  • 1.
    Hogue I, Jean J, Esteves A, Tanneti N, Scherer J, Enquist L. Functional Carboxy-Terminal Fluorescent Protein Fusion to Pseudorabies Virus Small Capsid Protein VP26. J Virol. 2018;92(1). PMCID: PMC5730785
    Reference Link
  • 1.
    Seyedsayamdost M, Xie J, T Y Chan C, Schultz P, Stubbe J. Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. J Am Chem Soc. 2007;129(48):15060–71. PMID: 17990884
    Reference Link
  • 1.
    Seyedsayamdost M, Case R, Kolter R, Clardy J. The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. Nat Chem. 2011;3(4):331–5. PMCID: PMC3376411
    Reference Link
  • 1.
    Seyedsayamdost M, Traxler M, Zheng S-L, Kolter R, Clardy J. Structure and biosynthesis of amychelin, an unusual mixed-ligand siderophore from Amycolatopsis sp. AA4. J Am Chem Soc. 2011;133(30):11434–7. PMCID: PMC3144690
    Reference Link
  • 1.
    Stevens A, Brown Z, Shah N, Sekar G, Cowburn D, Muir T. Design of a Split Intein with Exceptional Protein Splicing Activity. J Am Chem Soc. 2016;138(7):2162–5. PMCID: PMC4894280
    Reference Link
  • 1.
    Semmelhack M, Campagna S, Hwa C, Federle M, Bassler B. Boron binding with the quorum sensing signal AI-2 and analogues. Org Lett. 2004;6(15):2635–7. PMID: 15255709
    Reference Link
  • 1.
    Bassler B, Losick R. Bacterially speaking. Cell. 2006;125(2):237–46. PMID: 16630813
    Reference Link
  • 1.
    Chen G, Swem L, Swem D, Stauff D, O’Loughlin C, Jeffrey P, Bassler B, Hughson F. A strategy for antagonizing quorum sensing. Mol Cell. 2011;42(2):199–209. PMCID: PMC3092643
    Reference Link
  • 1.
    O’Loughlin C, Miller L, Siryaporn A, Drescher K, Semmelhack M, Bassler B. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A. 2013;110(44):17981–6. PMCID: PMC3816427
    Reference Link
  • 1.
    Miller L, O’Loughlin C, Zhang Z, Siryaporn A, Silpe J, Bassler B, Semmelhack M. Development of potent inhibitors of pyocyanin production in Pseudomonas aeruginosa. J Med Chem. 2015;58(3):1298–306. PMCID: PMC4332565
    Reference Link

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