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Yan N. A Glimpse of Membrane Transport through Structures-Advances in the Structural Biology of the GLUT Glucose Transporters. J Mol Biol. 2017;429(17):2710–2725. PMID: 28756087

Wang Y, Huang Y, Wang J, Cheng C, Huang W, Lu P, Xu Y-N, Wang P, Yan N, Shi Y. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 2009;462(7272):467–72. PMID: 19940917

Qi S, Pang Y, Hu Q, Liu Q, Li H, Zhou Y, He T, Liang Q, Liu Y, Yuan X, Luo G, Li H, Wang J, Yan N, Shi Y. Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell. 2010;141(3):446–57. PMID: 20434985

Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N. Structure of a fucose transporter in an outward-open conformation. Nature. 2010;467(7316):734–8. PMID: 20877283

Lu F, Li S, Jiang Y, Jiang J, Fan H, Lu G, Deng D, Dang S, Zhang X, Wang J, Yan N. Structure and mechanism of the uracil transporter UraA. Nature. 2011;472(7342):243–6. PMID: 21423164

Xie T, Ren R, Zhang Y- yuan, Pang Y, Yan C, Gong X, He Y, Li W, Miao D, Hao Q, Deng H, Wang Z, Wu J-W, Yan N. Molecular mechanism for inhibition of a critical component in the Arabidopsis thaliana abscisic acid signal transduction pathways, SnRK2.6, by protein phosphatase ABI1. J Biol Chem. 2012;287(1):794–802. PMCID: PMC3249133

He W, Brumos J, Li H, Ji Y, Ke M, Gong X, Zeng Q, Li W, Zhang X, An F, Wen X, Li P, Chu J, Sun X, Yan C, Yan N, Xie D-Y, Raikhel N, Yang Z, Stepanova A, Alonso J, Guo H. A small-molecule screen identifies L-kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth in Arabidopsis. Plant Cell. 2011;23(11):3944–60. PMCID: PMC3246337

Deng D, Yan C, Pan X, Mahfouz M, Wang J, Zhu J-K, Shi Y, Yan N. Structural basis for sequence-specific recognition of DNA by TAL effectors. Science. 2012;335(6069):720–3. PMCID: PMC3586824

Zhang X, Ren W, DeCaen P, Yan C, Tao X, Tang L, Wang J, Hasegawa K, Kumasaka T, He J, Wang J, Clapham D, Yan N. Crystal structure of an orthologue of the NaChBac voltage-gated sodium channel. Nature. 2012;486(7401):130–4. PMCID: PMC3979295

Sugihara J, Sun L, Yan N, Kaback R. Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy. Proc Natl Acad Sci U S A. 2012;109(37):14847–51. PMCID: PMC3443143

Sun L, Zeng X, Yan C, Sun X, Gong X, Rao Y, Yan N. Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature. 2012;490(7420):361–6. PMID: 23075985

Yin P, Li Q, Yan C, Liu Y, Liu J, Yu F, Wang Z, Long J, He J, Wang H-W, Wang J, Zhu J-K, Shi Y, Yan N. Structural basis for the modular recognition of single-stranded RNA by PPR proteins. Nature. 2013;504(7478):168–71. PMID: 24162847

Madej G, Sun L, Yan N, Kaback R. Functional architecture of MFS D-glucose transporters. Proc Natl Acad Sci U S A. 2014;111(7):E719–27. PMCID: PMC3932877

Deng D, Xu C, Sun P, Wu J, Yan C, Hu M, Yan N. Crystal structure of the human glucose transporter GLUT1. Nature. 2014;510(7503):121–5. PMID: 24847886

Wang J, Yan C, Li Y, Hirata K, Yamamoto M, Yan N, Hu Q. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014;24(12):1486–9. PMCID: PMC4260346

Yan Z, Bai X, Yan C, Wu J, Li Z, Xie T, Peng W, Yin C, Li X, Scheres S, Shi Y, Yan N. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015;517(7532):50–55. PMCID: PMC4338550

Deng D, Yan N. GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters. Protein Sci. 2016;25(3):546–58. PMCID: PMC4815417

Bai X-C, Yan Z, Wu J, Li Z, Yan N. The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening. Cell Res. 2016;26(9):995–1006. PMCID: PMC5034110

Deng D, Sun P, Yan C, Ke M, Jiang X, Xiong L, Ren W, Hirata K, Yamamoto M, Fan S, Yan N. Molecular basis of ligand recognition and transport by glucose transporters. Nature. 2015;526(7573):391–6. PMID: 26176916

Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, Pardon E, Steyaert J, Yan N, Kaback R. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016;113(44):12420–12425. PMCID: PMC5098631

Qian H, Zhao X, Cao P, Lei J, Yan N, Gong X. Structure of the Human Lipid Exporter ABCA1. Cell. 2017;169(7):1228–1239.e10. PMID: 28602350

Ducker G, Ghergurovich J, Mainolfi N, Suri V, Jeong S, Li S, Friedman A, Manfredi M, Gitai Z, Kim H, Rabinowitz J. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017;114(43):11404–11409. PMCID: PMC5664509

Jindal G, Goyal Y, Humphreys J, Yeung E, Tian K, Patterson V, He H, Burdine R, Goldsmith E, Shvartsman S. How activating mutations affect MEK1 regulation and function. J Biol Chem. 2017;292(46):18814–18820. PMCID: PMC5704466

Oppenheimer N, Stone H. Effect of Hydrodynamic Interactions on Reaction Rates in Membranes. Biophys J. 2017;113(2):440–447. PMCID: PMC5529315

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Dann G, Liszczak G, Bagert J, Müller M, Nguyen U, Wojcik F, Brown Z, Bos J, Panchenko T, Pihl R, Pollock S, Diehl K, Allis D, Muir T. ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature. 2017;548(7669):607–611. PMCID: PMC5777669

Lynch E, Hicks D, Shepherd M, Endrizzi J, Maker A, Hansen J, Barry R, Gitai Z, Baldwin E, Kollman J. Human CTP synthase filament structure reveals the active enzyme conformation. Nat Struct Mol Biol. 2017;24(6):507–514. PMCID: PMC5472220

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