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Mice, Transgenic

  • 1.
    Pisano T, Dhanerawala Z, Kislin M, Bakshinskaya D, Engel E, Hansen E, Hoag A, Lee J, de Oude N, Venkataraju K, Verpeut J, Hoebeek F, Richardson B, Boele H-J, Wang S. Homologous organization of cerebellar pathways to sensory, motor, and associative forebrain. Cell Rep. 2021;36(12):109721. PMCID: PMC8506234
    Reference Link
  • 1.
    Sugiura A, Andrejeva G, Voss K, Heintzman D, Xu X, Madden M, Ye X, Beier K, Chowdhury N, Wolf M, Young A, Greenwood D, Sewell A, Shahi S, Freedman S, Cameron A, Foerch P, Bourne T, García-Cañaveras J, Karijolich J, Newcomb D, Mangalam A, Rabinowitz J, Rathmell J. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022;55(1):65–81.e9. PMCID: PMC8755618
    Reference Link
  • 1.
    Verma A, Jena S, Isakov D, Aoki K, Toettcher J, Engelhardt B. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021;118(32). PMCID: PMC8364135
    Reference Link
  • 1.
    Liu Y, Maya S, Ploss A. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 2021;13(5). PMCID: PMC8146732
    Reference Link
  • 1.
    Chini C, Peclat T, Warner G, Kashyap S, Espindola-Netto J, de Oliveira G, Gomez L, Hogan K, Tarragó M, Puranik A, Agorrody G, Thompson K, Dang K, Clarke S, Childs B, Kanamori K, Witte M, Vidal P, Kirkland A, De Cecco M, Chellappa K, McReynolds M, Jankowski C, Tchkonia T, Kirkland J, Sedivy J, van Deursen J, Baker D, van Schooten W, Rabinowitz J, Baur J, Chini E. CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD and NMN levels. Nat Metab. 2020;2(11):1284–1304. PMCID: PMC8752031
    Reference Link
  • 1.
    Brown R, Tegtmeyer B, Sheldon J, Khera T, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran F, Krey T, Ströh L, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr A, McClure P, Randall G, Baktash Y, Ploss A, Thi V, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice C, Pietschmann T. Liver-expressed and limit hepatitis C virus cross-species transmission to mice. Sci Adv. 2020;6(45). PMCID: PMC7673688
    Reference Link
  • 1.
    Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz J. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020;2(7):586–593. PMCID: PMC8020332
    Reference Link
  • 1.
    Gu B, Posfai E, Gertsenstein M, Rossant J. Efficient Generation of Large-Fragment Knock-In Mouse Models Using 2-Cell (2C)-Homologous Recombination (HR)-CRISPR. Curr Protoc Mouse Biol. 2020;10(1):e67. PMID: 31912993
    Reference Link
  • 1.
    Zanin J, Verpeut J, Li Y, Shiflett M, Wang S, Santhakumar V, Friedman W. The p75NTR Influences Cerebellar Circuit Development and Adult Behavior via Regulation of Cell Cycle Duration of Granule Cell Progenitors. J Neurosci. 2019;39(46):9119–9129. PMCID: PMC6855675
    Reference Link
  • 1.
    Yan R, Zhang J, Park H-J, Park E, Oh S, Zheng H, Junn E, Voronkov M, Stock J, Mouradian M. Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson’s disease and DLB. Proc Natl Acad Sci U S A. 2018;115(51):E12053-E12062. PMCID: PMC6304960
    Reference Link
  • 1.
    Mayer A, Zhang Y, Perelson A, Wingreen N. Regulation of T cell expansion by antigen presentation dynamics. Proc Natl Acad Sci U S A. 2019;116(13):5914–5919. PMCID: PMC6442601
    Reference Link
  • 1.
    Gaska J, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods Mol Biol. 2019;1911:481–503. PMCID: PMC6699619
    Reference Link
  • 1.
    Dixit A, Parnas O, Li B, Chen J, Fulco C, Jerby-Arnon L, Marjanovic N, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman T, Lander E, Weissman J, Friedman N, Regev A iv. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016;167(7):1853–1866.e17. PMCID: PMC5181115
    Reference Link
  • 1.
    Winer B, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low B, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais M-A, Frankel A, Chiriboga L, Cullen J, Nahass R, Lutgehetmann M, Toettcher J, Wiles M, Schwartz R, Ploss A. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med. 2018;10(447). PMCID: PMC6337727
    Reference Link
  • 1.
    Douam F, Ploss A. The use of humanized mice for studies of viral pathogenesis and immunity. Curr Opin Virol. 2018;29:62–71. PMCID: PMC5940492
    Reference Link
  • 1.
    Sauls K, Greco T, Wang L, Zou M, Villasmil M, Qian L, Cristea I, Conlon F. Initiating Events in Direct Cardiomyocyte Reprogramming. Cell Rep. 2018;22(7):1913–1922. PMCID: PMC6045814
    Reference Link
  • 1.
    Zheng H, Bae Y, Kasimir-Bauer S, Tang R, Chen J, Ren G, Yuan M, Esposito M, Li W, Wei Y, Shen M, Zhang L, Tupitsyn N, Pantel K, King C, Sun J, Moriguchi J, Jun H, Coxon A, Lee B, Kang Y. Therapeutic Antibody Targeting Tumor- and Osteoblastic Niche-Derived Jagged1 Sensitizes Bone Metastasis to Chemotherapy. Cancer Cell. 2017;32(6):731–747.e6. PMCID: PMC5729937
    Reference Link
  • 1.
    Heck B, Devenport D. Trans-endocytosis of Planar Cell Polarity Complexes during Cell Division. Curr Biol. 2017;27(23):3725–3733.e4. PMCID: PMC5728440
    Reference Link
  • 1.
    Meshulam L, Gauthier J, Brody C, Tank D, Bialek W. Collective Behavior of Place and Non-place Neurons in the Hippocampal Network. Neuron. 2017;96(5):1178–1191.e4. PMCID: PMC5720931
    Reference Link
  • 1.
    Celià-Terrassa T, Liu D, Choudhury A, Hang X, Wei Y, Zamalloa J, Alfaro-Aco R, Chakrabarti R, Jiang Y-Z, Koh B, Smith H, DeCoste C, Li J-J, Shao Z-M, Kang Y. Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis. Nat Cell Biol. 2017;19(6):711–723. PMCID: PMC5481166
    Reference Link
  • 1.
    Giovannucci A, Badura A, Deverett B, Najafi F, Pereira T, Gao Z, Ozden I, Kloth A, Pnevmatikakis E, Paninski L, De Zeeuw C, Medina J, Wang S. Cerebellar granule cells acquire a widespread predictive feedback signal during motor learning. Nat Neurosci. 2017;20(5):727–734. PMCID: PMC5704905
    Reference Link
  • 1.
    Song A, Charles A, Koay S, Gauthier J, Thiberge S, Pillow J, Tank D. Volumetric two-photon imaging of neurons using stereoscopy (vTwINS). Nat Methods. 2017;14(4):420–426. PMCID: PMC5551981
    Reference Link
  • 1.
    Pomeranz L, Ekstrand M, Latcha K, Smith G, Enquist L, Friedman J. Gene Expression Profiling with Cre-Conditional Pseudorabies Virus Reveals a Subset of Midbrain Neurons That Participate in Reward Circuitry. J Neurosci. 2017;37(15):4128–4144. PMCID: PMC5391685
    Reference Link
  • 1.
    Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, Ploss A. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017;91(4). PMCID: PMC5286898
    Reference Link
  • 1.
    Chikina M, Gerald C, Li X, Ge Y, Pincas H, Nair V, Wong A, Krishnan A, Troyanskaya O, Raymond D, Saunders-Pullman R, Bressman S, Yue Z, Sealfon S. Low-variance RNAs identify Parkinson’s disease molecular signature in blood. Mov Disord. 2015;30(6):813–21. PMCID: PMC4439364
    Reference Link
  • 1.
    Cope E, Briones B, Brockett A, Martinez S, Vigneron P-A, Opendak M, Wang S, Gould E. Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism. eNeuro. 2016;3(5). PMCID: PMC5066262
    Reference Link
  • 1.
    Siu E, Ploss A. Modeling malaria in humanized mice: opportunities and challenges. Ann N Y Acad Sci. 2015;1342:29–36. PMID: 25678404
    Reference Link
  • 1.
    Kim H, Pang M-F, Varner V, Kojima L, Miller E, Radisky D, Nelson C. Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung. Dev Cell. 2015;34(6):719–26. PMCID: PMC4589145
    Reference Link
  • 1.
    Devenport D, Oristian D, Heller E, Fuchs E. Mitotic internalization of planar cell polarity proteins preserves tissue polarity. Nat Cell Biol. 2011;13(8):893–902. PMCID: PMC3149741
    Reference Link
  • 1.
    Douam F, Gaska J, Winer B, Ding Q, von Schaewen M, Ploss A. Genetic Dissection of the Host Tropism of Human-Tropic Pathogens. Annu Rev Genet. 2015;49:21–45. PMCID: PMC5075990
    Reference Link
  • 1.
    Rickgauer J, Deisseroth K, Tank D. Simultaneous cellular-resolution optical perturbation and imaging of place cell firing fields. Nat Neurosci. 2014;17(12):1816–24. PMCID: PMC4459599
    Reference Link
  • 1.
    Piochon C, Kloth A, Grasselli G, Titley H, Nakayama H, Hashimoto K, Wan V, Simmons D, Eissa T, Nakatani J, Cherskov A, Miyazaki T, Watanabe M, Takumi T, Kano M, Wang S, Hansel C. Cerebellar plasticity and motor learning deficits in a copy-number variation mouse model of autism. Nat Commun. 2014;5:5586. PMCID: PMC4243533
    Reference Link
  • 1.
    Waldron L, Steimle J, Greco T, Gomez N, Dorr K, Kweon J, Temple B, Yang X, Wilczewski C, Davis I, Cristea I, Moskowitz I, Conlon F. The Cardiac TBX5 Interactome Reveals a Chromatin Remodeling Network Essential for Cardiac Septation. Dev Cell. 2016;36(3):262–75. PMCID: PMC4920128
    Reference Link

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