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1.Li X, Hui S, Mirek E, Jonsson W, Anthony T, Lee W, Zeng X, Jang C, Rabinowitz J. Circulating metabolite homeostasis achieved through mass action. Nat Metab. 2022;4(1):141–152. PMCID: PMC9244777 Reference Link
1.Tamura T, Zhang J, Madan V, Biswas A, Schwoerer M, Cafiero T, Heller B, Wang W, Ploss A. Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4. Emerg Microbes Infect. 2022;11(1):227–239. PMCID: PMC8745371 Reference Link
1.Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias J, Siebel C, Blanco M, Klein-Szanto A, Lengner C, Welm A, Kang Y, Chakrabarti R. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021;12(1):432. PMCID: PMC7813834 Reference Link
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1.Ringel A, Drijvers J, Baker G, Catozzi A, García-Cañaveras J, Gassaway B, Miller B, Juneja V, Nguyen T, Joshi S, Yao C-H, Yoon H, Sage P, LaFleur M, Trombley J, Jacobson C, Maliga Z, Gygi S, Sorger P, Rabinowitz J, Sharpe A, Haigis M. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020;183(7):1848–1866.e26. PMCID: PMC8064125 Reference Link
1.Chini C, Peclat T, Warner G, Kashyap S, Espindola-Netto J, de Oliveira G, Gomez L, Hogan K, Tarragó M, Puranik A, Agorrody G, Thompson K, Dang K, Clarke S, Childs B, Kanamori K, Witte M, Vidal P, Kirkland A, De Cecco M, Chellappa K, McReynolds M, Jankowski C, Tchkonia T, Kirkland J, Sedivy J, van Deursen J, Baker D, van Schooten W, Rabinowitz J, Baur J, Chini E. CD38 ecto-enzyme in immune cells is induced during aging and regulates NAD and NMN levels. Nat Metab. 2020;2(11):1284–1304. PMCID: PMC8752031 Reference Link
1.Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram U, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, Xia L, Welm A, Bielenberg D, Camphausen K, Kang Y, Chen H. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. J Clin Invest. 2021;131(1). PMCID: PMC7773373 Reference Link
1.Jang C, Wada S, Yang S, Gosis B, Zeng X, Zhang Z, Shen Y, Lee G, Arany Z, Rabinowitz J. The small intestine shields the liver from fructose-induced steatosis. Nat Metab. 2020;2(7):586–593. PMCID: PMC8020332 Reference Link
1.Guan D, Xiong Y, Trinh T, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz J, Lazar M. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020;369(6509):1388–1394. PMCID: PMC7849028 Reference Link
1.Lanaspa M, Andres-Hernando A, Orlicky D, Cicerchi C, Jang C, Li N, Milagres T, Kuwabara M, Wempe M, Rabinowitz J, Johnson R, Tolan D. Ketohexokinase C blockade ameliorates fructose-induced metabolic dysfunction in fructose-sensitive mice. J Clin Invest. 2018;128(6):2226–2238. PMCID: PMC5983342 Reference Link
1.Liu Q, Johnson E, Lam R, Wang Q, Ye H, Wilson E, Minhas P, Liu L, Swarovski M, Tran S, Wang J, Mehta S, Yang X, Rabinowitz J, Yang S, Shamloo M, Mueller C, James M, Andreasson K. Peripheral TREM1 responses to brain and intestinal immunogens amplify stroke severity. Nat Immunol. 2019;20(8):1023–1034. PMCID: PMC6778967 Reference Link
1.Minhas P, Liu L, Moon P, Joshi A, Dove C, Mhatre S, Contrepois K, Wang Q, Lee B, Coronado M, Bernstein D, Snyder M, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz J, Andreasson K. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019;20(1):50–63. PMCID: PMC6768398 Reference Link
1.Zhuo W, Liu Y, Li S, Guo D, Sun Q, Jin J, Rao X, Li M, Sun M, Jiang M, Xu Y, Teng L, Jin Y, Si J, Liu W, Kang Y, Zhou T. Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Gastroenterology. 2019;156(3):676–691.e11. PMID: 30445010 Reference Link
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1.Miller R, Shi Y, Lu W, Pirman D, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett K, Park J, Zhang Y, Holland W, Rabinowitz J, Birnbaum M. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nat Med. 2018;24(4):518–524. PMCID: PMC6089616 Reference Link
1.Kim H, Raffler J, Lu W, Lee J-J, Abbey D, Saleheen D, Rabinowitz J, Bennett M, Hand N, Brown C, Rader D. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017;101(4):489–502. PMCID: PMC5630162 Reference Link
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1.Gong Y, Cao R, Ding G, Hong S, Zhou W, Lu W, Damle M, Fang B, Wang C, Qian J, Lie N, Lanzillotta C, Rabinowitz J, Sun Z. Integrated omics approaches to characterize a nuclear receptor corepressor-associated histone deacetylase in mouse skeletal muscle. Mol Cell Endocrinol. 2018;471:22–32. PMCID: PMC5702591 Reference Link
1.Cetera M, Leybova L, Woo F, Deans M, Devenport D. Planar cell polarity-dependent and independent functions in the emergence of tissue-scale hair follicle patterns. Dev Biol. 2017;428(1):188–203. PMCID: PMC5549468 Reference Link
1.Duncan J, Stoller M, Francl A, Tissir F, Devenport D, Deans M. Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development. Dev Biol. 2017;423(2):126–137. PMCID: PMC5369242 Reference Link
1.Titchenell P, Quinn W, Lu M, Chu Q, Lu W, Li C, Chen H, Monks B, Chen J, Rabinowitz J, Birnbaum M. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metab. 2016;23(6):1154–1166. PMCID: PMC4909537 Reference Link
1.Teng X, Emmett M, Lazar M, Goldberg E, Rabinowitz J. Lactate Dehydrogenase C Produces S-2-Hydroxyglutarate in Mouse Testis. ACS Chem Biol. 2016;11(9):2420–7. PMCID: PMC5317044 Reference Link
1.Frederick D, Loro E, Liu L, Davila A, Chellappa K, Silverman I, Quinn W, Gosai S, Tichy E, Davis J, Mourkioti F, Gregory B, Dellinger R, Redpath P, Migaud M, Nakamaru-Ogiso E, Rabinowitz J, Khurana T, Baur J. Loss of NAD Homeostasis Leads to Progressive and Reversible Degeneration of Skeletal Muscle. Cell Metab. 2016;24(2):269–82. PMCID: PMC4985182 Reference Link
1.Papazyan R, Sun Z, Kim Y, Titchenell P, Hill D, Lu W, Damle M, Wan M, Zhang Y, Briggs E, Rabinowitz J, Lazar M. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metab. 2016;24(6):863–874. PMCID: PMC5159233 Reference Link
1.Winer B, Huang T, Low B, Avery C, Pais M-A, Hrebikova G, Siu E, Chiriboga L, Wiles M, Ploss A. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 2017;502:63–72. PMCID: PMC5414730 Reference Link
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1.Hjeij R, Onoufriadis A, Watson C, Slagle C, Klena N, Dougherty G, Kurkowiak M, Loges N, Diggle C, Morante N, Gabriel G, Lemke K, Li Y, Pennekamp P, Menchen T, Konert F, Marthin J, Mans D, Letteboer S, Werner C, Burgoyne T, Westermann C, Rutman A, Carr I, O’Callaghan C, Moya E, Chung E, UK10K Consortium, Sheridan E, Nielsen K, Roepman R, Bartscherer K, Burdine R, Lo C, Omran H, Mitchison H. CCDC151 mutations cause primary ciliary dyskinesia by disruption of the outer dynein arm docking complex formation. Am J Hum Genet. 2014;95(3):257–74. PMCID: PMC4157146 Reference Link