1.Ravindran P, McFann S, Thornton R, Toettcher J. A synthetic gene circuit for imaging-free detection of signaling pulses. Cell Syst. 2022;13(2):131–142.e13. PMCID: PMC8857027 Reference Link
1.Verma A, Jena S, Isakov D, Aoki K, Toettcher J, Engelhardt B. A self-exciting point process to study multicellular spatial signaling patterns. Proc Natl Acad Sci U S A. 2021;118(32). PMCID: PMC8364135 Reference Link
1.McFann S, Dutta S, Toettcher J, Shvartsman S. Temporal integration of inductive cues on the way to gastrulation. Proc Natl Acad Sci U S A. 2021;118(23). PMCID: PMC8201965 Reference Link
1.Marmion R, Yang L, Goyal Y, Jindal G, Wetzel J, Singh M, Schüpbach T, Shvartsman S. Molecular mechanisms underlying cellular effects of human MEK1 mutations. Mol Biol Cell. 2021;32(9):974–983. PMCID: PMC8108529 Reference Link
1.Johnson H, Djabrayan N, Shvartsman S, Toettcher J. Optogenetic Rescue of a Patterning Mutant. Curr Biol. 2020;30(17):3414–3424.e3. PMCID: PMC7730203 Reference Link
1.Goglia A, Wilson M, Jena S, Silbert J, Basta L, Devenport D, Toettcher J. A Live-Cell Screen for Altered Erk Dynamics Reveals Principles of Proliferative Control. Cell Syst. 2020;10(3):240–253.e6. PMCID: PMC7540725 Reference Link
1.Keenan S, Blythe S, Marmion R, Djabrayan N, Wieschaus E, Shvartsman S. Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. Dev Cell. 2020;52(6):794–801.e4. PMCID: PMC7161736 Reference Link
1.Smits C, Shvartsman S. The design and logic of terminal patterning in Drosophila. Curr Top Dev Biol. 2020;137:193–217. PMID: 32143743 Reference Link
1.Paul S, Yang L, Mattingly H, Goyal Y, Shvartsman S, Veraksa A. Activation-induced substrate engagement in ERK signaling. Mol Biol Cell. 2020;31(4):235–243. PMCID: PMC7183763 Reference Link
1.Patel A, Yeung E, McGuire S, Wu A, Toettcher J, Burdine R, Shvartsman S. Optimizing photoswitchable MEK. Proc Natl Acad Sci U S A. 2019;116(51):25756–25763. PMCID: PMC6926043 Reference Link
1.Patel A, Shvartsman S. Outstanding questions in developmental ERK signaling. Development. 2018;145(14). PMCID: PMC6078328 Reference Link
1.Lim B, Dsilva C, Kevrekidis I, Shvartsman S. Reconstructing ERK Signaling in the Drosophila Embryo from Fixed Images. Methods Mol Biol. 2017;1487:337–351. PMCID: PMC6557116 Reference Link
1.Johnson H, Goyal Y, Pannucci N, Schüpbach T, Shvartsman S, Toettcher J. The Spatiotemporal Limits of Developmental Erk Signaling. Dev Cell. 2017;40(2):185–192. PMCID: PMC5289754 Reference Link
1.Jindal G, Goyal Y, Yamaya K, Futran A, Kountouridis I, Balgobin C, Schüpbach T, Burdine R, Shvartsman S. In vivo severity ranking of Ras pathway mutations associated with developmental disorders. Proc Natl Acad Sci U S A. 2017;114(3):510–515. PMCID: PMC5255624 Reference Link
1.Mattingly H, Chen J, Arur S, Shvartsman S. A Transport Model for Estimating the Time Course of ERK Activation in the C. elegans Germline. Biophys J. 2015;109(11):2436–45. PMCID: PMC4675862 Reference Link
1.Kim J, Rose M. Stable Pseudohyphal Growth in Budding Yeast Induced by Synergism between Septin Defects and Altered MAP-kinase Signaling. PLoS Genet. 2015;11(12):e1005684. PMCID: PMC4671653 Reference Link
1.Lim B, Dsilva C, Levario T, Lu H, Schüpbach T, Kevrekidis I, Shvartsman S. Dynamics of Inductive ERK Signaling in the Drosophila Embryo. Curr Biol. 2015;25(13):1784–90. PMCID: PMC4675133 Reference Link
1.Toettcher J, Weiner O, Lim W. Using optogenetics to interrogate the dynamic control of signal transmission by the Ras/Erk module. Cell. 2013;155(6):1422–34. PMCID: PMC3925772 Reference Link
1.Jindal G, Goyal Y, Burdine R, Rauen K, Shvartsman S. RASopathies: unraveling mechanisms with animal models. Dis Model Mech. 2015;8(8):769–82. PMCID: PMC4527292 Reference Link
