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Humans

  • 1.
    King S, Singh M. Primate protein-ligand interfaces exhibit significant conservation and unveil human-specific evolutionary drivers. PLoS Comput Biol. 2023;19(3):e1010966. PMCID: PMC10035887
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  • 1.
    Chen Z, Kang Y. Cold snap for cancer: cold-induced brown fat thermogenesis starves tumor growth. Signal Transduct Target Ther. 2023;8(1):10. PMCID: PMC9826784
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  • 1.
    Cashen K, Sutton R, Reeder R, Ahmed T, Bell M, Berg R, Burns C, Carcillo J, Carpenter T, Dean M, Diddle W, Federman M, Fink E, Franzon D, Frazier A, Friess S, Graham K, Hall M, Hehir D, Horvat C, Huard L, KirkpatrickN T, Maa T, Manga A, McQuillen P, Morgan R, Mourani P, Nadkarni V, Naim M, Notterman D, Page K, Pollack M, Qunibi D, Sapru A, Schneiter C, Sharron M, Srivastava N, Viteri S, Wessel D, Wolfe H, Yates A, Zuppa A, Meert K, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and National Heart Lung and Blood Institute ICU-RESUScitation Project Investigators. Calcium use during paediatric in-hospital cardiac arrest is associated with worse outcomes. Resuscitation. 2023;185:109673. PMCID: PMC10065910
    Reference Link
  • 1.
    Berg R, Morgan R, Reeder R, Ahmed T, Bell M, Bishop R, Bochkoris M, Burns C, Carcillo J, Carpenter T, Dean M, Diddle W, Federman M, Fernandez R, Fink E, Franzon D, Frazier A, Friess S, Graham K, Hall M, Hehir D, Horvat C, Huard L, Maa T, Manga A, McQuillen P, Meert K, Mourani P, Nadkarni V, Naim M, Notterman D, Palmer C, Pollack M, Sapru A, Schneiter C, Sharron M, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Wolfe H, Yates A, Zuppa A, Sutton R. Diastolic Blood Pressure Threshold During Pediatric Cardiopulmonary Resuscitation and Survival Outcomes: A Multicenter Validation Study. Crit Care Med. 2023;51(1):91–102. PMCID: PMC9970166
    Reference Link
  • 1.
    Cappuccio A, Chawla D, Chen X, Rubenstein A, Cheng W, Mao W, Burke T, Tsalik E, Petzold E, Henao R, McClain M, Woods C, Chikina M, Troyanskaya O, Sealfon S, Kleinstein S, Zaslavsky E. Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature. Cell Syst. 2022;13(12):989–1001.e8. PMID: 36549275
    Reference Link
  • 1.
    Meyer C, Seath C, Knutson S, Lu W, Rabinowitz J, MacMillan D. Photoproximity Labeling of Sialylated Glycoproteins (GlycoMap) Reveals Sialylation-Dependent Regulation of Ion Transport. J Am Chem Soc. 2022;144(51):23633–23641. PMID: 36525649
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  • 1.
    Arich S, Haba Y, Assaid N, Fritz M, McBride C, Weill M, Taki H, Sarih M, Labbé P. No association between habitat, autogeny and genetics in Moroccan Culex pipiens populations. Parasit Vectors. 2022;15(1):405. PMCID: PMC9635193
    Reference Link
  • 1.
    Rose N, Dabo S, Leal S, Sylla M, Diagne C, Faye O, Faye O, Sall A, McBride C, Lambrechts L. Enhanced mosquito vectorial capacity underlies the Cape Verde Zika epidemic. PLoS Biol. 2022;20(10):e3001864. PMCID: PMC9604947
    Reference Link
  • 1.
    Sauerwald N, Zhang Z, Ramos I, Nair V, Soares-Schanoski A, Ge Y, Mao W, Alshammary H, Gonzalez-Reiche A, van de Guchte A, Goforth C, Lizewski R, Lizewski S, Amper M, Vasoya M, Seenarine N, Guevara K, Marjanovic N, Miller C, Nudelman G, Schilling M, Sealfon R, Termini M, Vangeti S, Weir D, Zaslavsky E, Chikina M, Wu Y, van Bakel H, Letizia A, Sealfon S, Troyanskaya O. Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection. Cell Syst. 2022;13(11):924–931.e4. PMCID: PMC9623453
    Reference Link
  • 1.
    Omenn G, Lane L, Overall C, Pineau C, Packer N, Cristea I, Lindskog C, Weintraub S, Orchard S, Roehrl M, Nice E, Liu S, Bandeira N, Chen Y-J, Guo T, Aebersold R, Moritz R, Deutsch E. The 2022 Report on the Human Proteome from the HUPO Human Proteome Project. J Proteome Res. 2023;22(4):1024–1042. PMCID: PMC10081950
    Reference Link
  • 1.
    Murashige D, Jung J, Neinast M, Levin M, Chu Q, Lambert J, Garbincius J, Kim B, Hoshino A, Marti-Pamies I, McDaid K, Shewale S, Flam E, Yang S, Roberts E, Li L, Morley M, Bedi K, Hyman M, Frankel D, Margulies K, Assoian R, Elrod J, Jang C, Rabinowitz J, Arany Z. Extra-cardiac BCAA catabolism lowers blood pressure and protects from heart failure. Cell Metab. 2022;34(11):1749–1764.e7. PMCID: PMC9633425
    Reference Link
  • 1.
    Horvat C, Fabio A, Nagin D, Banks R, Qin Y, Park H-J, Kernan K, Canna S, Berg R, Wessel D, Pollack M, Meert K, Hall M, Newth C, Lin J, Doctor A, Shanley T, Cornell T, Harrison R, Zuppa A, Reeder R, Sward K, Holubkov R, Notterman D, Dean M, Carcillo J, Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network. Mortality Risk in Pediatric Sepsis Based on C-reactive Protein and Ferritin Levels. Pediatr Crit Care Med. 2022;23(12):968–979. PMCID: PMC9722561
    Reference Link
  • 1.
    Cota V, Sohrabi S, Kaletsky R, Murphy C. Oocyte mitophagy is critical for extended reproductive longevity. PLoS Genet. 2022;18(9):e1010400. PMCID: PMC9524673
    Reference Link
  • 1.
    Shen M, Kang Y. Cancer fitness genes: emerging therapeutic targets for metastasis. Trends Cancer. 2023;9(1):69–82. PMID: 36184492
    Reference Link
  • 1.
    Cheng K, Burdine R, Dickinson M, Ekker S, Lin A, Lloyd K, Lutz C, MacRae C, Morrison J, O’Connor D, Postlethwait J, Rogers C, Sanchez S, Simpson J, Talbot W, Wallace D, Weimer J, Bellen H. Promoting validation and cross-phylogenetic integration in model organism research. Dis Model Mech. 2022;15(9). PMCID: PMC9531892
    Reference Link
  • 1.
    Amin J, Zhao T, Yang H, Shaevitz J. Multicolor multifocal 3D microscopy using in-situ optimization of a spatial light modulator. Sci Rep. 2022;12(1):16343. PMCID: PMC9522655
    Reference Link
  • 1.
    Caragiulo A, Gaughran S, Duncan N, Nagy C, Weckel M, vonHoldt B. Coyotes in New York City Carry Variable Genomic Dog Ancestry and Influence Their Interactions with Humans. Genes (Basel). 2022;13(9). PMCID: PMC9498729
    Reference Link
  • 1.
    Nguyen T, Costa E, Deibert T, Reyes J, Keber F, Tomschik M, Stadlmeier M, Gupta M, Kumar C, Cruz E, Amodeo A, Gatlin J, Wühr M. Differential nuclear import sets the timing of protein access to the embryonic genome. Nat Commun. 2022;13(1):5887. PMCID: PMC9537182
    Reference Link
  • 1.
    French H, Pitre E, Oade M, Elshina E, Bisht K, King A, Bauer D, Velthuis A. Transient RNA structures cause aberrant influenza virus replication and innate immune activation. Sci Adv. 2022;8(36):eabp8655. PMCID: PMC9462681
    Reference Link
  • 1.
    Jiang X, Yan N, Deng D, Yan C. Structural aspects of the glucose and monocarboxylate transporters involved in the Warburg effect. IUBMB Life. 2022;74(12):1180–1199. PMID: 36082803
    Reference Link
  • 1.
    Taylor I, Murray-Nerger L, Greco T, Liu D, Cristea I, Bassler B. Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa. mBio. 2022;13(5):e0155922. PMCID: PMC9600345
    Reference Link
  • 1.
    Morgan R, Wolfe H, Reeder R, Alvey J, Frazier A, Friess S, Maa T, McQuillen P, Meert K, Nadkarni V, Sharron M, Siems A, Yates A, Ahmed T, Bell M, Bishop R, Bochkoris M, Burns C, Carcillo J, Carpenter T, Dean M, Diddle W, Federman M, Fernandez R, Fink E, Franzon D, Hall M, Hehir D, Horvat C, Huard L, Manga A, Mourani P, Naim M, Notterman D, Pollack M, Sapru A, Schneiter C, Srivastava N, Tabbutt S, Tilford B, Viteri S, Wessel D, Zuppa A, Berg R, Sutton R. The Temporal Association of the COVID-19 Pandemic and Pediatric Cardiopulmonary Resuscitation Quality and Outcomes. Pediatr Crit Care Med. 2022;23(11):908–918. PMCID: PMC9624237
    Reference Link
  • 1.
    Suzuki S, Geri J, Knutson S, Bell-Temin H, Tamura T, Fernández D, Lovett G, Till N, Heller B, Guo J, MacMillan D, Ploss A. Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap. J Am Chem Soc. 2022;144(36):16604–16611. PMCID: PMC9469761
    Reference Link
  • 1.
    Chen H, Zhan M, Liu J, Liu Z, Shen M, Yang F, Kang Y, Yin F, Li Z. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022;65(18):12188–12199. PMID: 36044768
    Reference Link
  • 1.
    Mitchener M, Muir T. Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation. Mol Cell. 2022;82(16):2925–2938. PMCID: PMC9482148
    Reference Link
  • 1.
    Cashen K, Reeder R, Ahmed T, Bell M, Berg R, Burns C, Carcillo J, Carpenter T, Dean M, Diddle W, Federman M, Fink E, Frazier A, Friess S, Graham K, Hall M, Hehir D, Horvat C, Huard L, Maa T, Manga A, McQuillen P, Morgan R, Mourani P, Nadkarni V, Naim M, Notterman D, Palmer C, Pollack M, Schneiter C, Sharron M, Srivastava N, Wessel D, Wolfe H, Yates A, Zuppa A, Sutton R, Meert K, for the Eunice Kennedy Shriver National Institute of Child Health and Human Development Collaborative Pediatric Critical Care Research Network (CPCCRN) and. Sodium Bicarbonate Use During Pediatric Cardiopulmonary Resuscitation: A Secondary Analysis of the ICU-RESUScitation Project Trial. Pediatr Crit Care Med. 2022;23(10):784–792. PMCID: PMC9529841
    Reference Link
  • 1.
    Ruiz N, Silhavy T. How Escherichia coli Became the Flagship Bacterium of Molecular Biology. J Bacteriol. 2022;204(9):e0023022. PMCID: PMC9487582
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  • 1.
    Jankowski C, Rabinowitz J. Selenium Modulates Cancer Cell Response to Pharmacologic Ascorbate. Cancer Res. 2022;82(19):3486–3498. PMCID: PMC9532358
    Reference Link
  • 1.
    Lizewski R, Sealfon R, Park S, Smith G, Porter C, Gonzalez-Reiche A, Ge Y, Miller C, Goforth C, Pincas H, Termini M, Ramos I, Nair V, Lizewski S, Alshammary H, Cer R, Chen H, George M-C, Arnold C, Glang L, Long K, Malagon F, Marayag J, Nunez E, Rice G, Ana E, Schilling M, Smith D, Sugiharto V, Sun P, van de Guchte A, Khan Z, Dutta J, Vangeti S, Voegtly L, Weir D, Metcalf J, Troyanskaya O, Bishop-Lilly K, Grenfell B, van Bakel H, Letizia A, Sealfon S. SARS-CoV-2 Outbreak Dynamics in an Isolated US Military Recruit Training Center With Rigorous Prevention Measures. Epidemiology. 2022;33(6):797–807. PMCID: PMC9531985
    Reference Link
  • 1.
    Bushin L, Covington B, Clark K, Caruso A, Seyedsayamdost M. Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nat Chem Biol. 2022;18(10):1135–1143. PMCID: 6686864
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  • 1.
    Covington B, Seyedsayamdost M. Vitamin B3 Triggers Biosynthesis of Secondary Metabolite Dormancy Signals in . J Am Chem Soc. 2022;144(33):14997–15001. PMID: 35969232
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  • 1.
    Taylor I, Jeffrey P, Moustafa D, Goldberg J, Bassler B. The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against . Biochemistry. 2022;61(17):1894–1903. PMCID: PMC9454246
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  • 1.
    Cook K, Tsopurashvili E, Needham J, Thompson S, Cristea I. Restructured membrane contacts rewire organelles for human cytomegalovirus infection. Nat Commun. 2022;13(1):4720. PMCID: PMC9366835
    Reference Link
  • 1.
    Blostein F, Fisher J, Dou J, Schneper L, Ware E, Notterman D, Mitchell C, Bakulski K. Polymethylation scores for prenatal maternal smoke exposure persist until age 15 and are detected in saliva in the Fragile Families and Child Wellbeing cohort. Epigenetics. 2022;17(13):2223–2240. PMCID: PMC9665138
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  • 1.
    Bisht K, Velthuis A. Decoding the Role of Temperature in RNA Virus Infections. mBio. 2022;13(5):e0202122. PMCID: PMC9600459
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  • 1.
    Zhang Y, Xu Y, Lu W, Li J, Yu S, Brown E, Stanger B, Rabinowitz J, Yang X. G6PD-mediated increase in de novo NADP biosynthesis promotes antioxidant defense and tumor metastasis. Sci Adv. 2022;8(29):eabo0404. PMCID: PMC9299539
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  • 1.
    Arguello E, Li A, Sun X, Eggert T, Mairhofer E, Kleiner R. Reactivity-dependent profiling of RNA 5-methylcytidine dioxygenases. Nat Commun. 2022;13(1):4176. PMCID: PMC9296451
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  • 1.
    Lim A, Menegatti S, Bustamante J, Le Bourhis L, Allez M, Rogge L, Casanova J-L, Yssel H, Di Santo J. IL-12 drives functional plasticity of human group 2 innate lymphoid cells. J Exp Med. 2016;213(4):569–83. PMCID: PMC4821648
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  • 1.
    Lim A, Verrier T, Vosshenrich C, Di Santo J. Developmental options and functional plasticity of innate lymphoid cells. Curr Opin Immunol. 2017;44:61–68. PMID: 28359987
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    Lim A, Li Y, Lopez-Lastra S, Stadhouders R, Paul F, Casrouge A, Serafini N, Puel A, Bustamante J, Surace L, Masse-Ranson G, David E, Strick-Marchand H, Le Bourhis L, Cocchi R, Topazio D, Graziano P, Muscarella L, Rogge L, Norel X, Sallenave J-M, Allez M, Graf T, Hendriks R, Casanova J-L, Amit I, Yssel H, Di Santo J. Systemic Human ILC Precursors Provide a Substrate for Tissue ILC Differentiation. Cell. 2017;168(6):1086–1100.e10. PMID: 28283063
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    Lim A, Harrison O, Belkaid Y. Pre-birth memory. Nat Immunol. 2019;20(3):254–256. PMID: 30742077
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  • 1.
    Scheffler R, Bratton B, Gitai Z. Pseudomonas aeruginosa clinical blood isolates display significant phenotypic variability. PLoS One. 2022;17(7):e0270576. PMCID: PMC9258867
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  • 1.
    Kumar H, Jimah J, Misal S, Salinas N, Fried M, Schlesinger P, Tolia N. Implications of conformational flexibility, lipid binding, and regulatory domains in cell-traversal protein CelTOS for apicomplexan migration. J Biol Chem. 2022;298(9):102241. PMCID: PMC9400078
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  • 1.
    Do T, Thokkadam A, Leach R, Link J. Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in . ACS Chem Biol. 2022;17(8):2332–2343. PMCID: PMC9454059
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  • 1.
    Chen K, Wong A, Troyanskaya O, Zhou J. A sequence-based global map of regulatory activity for deciphering human genetics. Nat Genet. 2022;54(7):940–949. PMCID: PMC9279145
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    Travis S, Mahon B, Petry S. How Microtubules Build the Spindle Branch by Branch. Annu Rev Cell Dev Biol. 2022;38:1–23. PMCID: PMC9619725
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  • 1.
    Lindell R, Zhang D, Bush J, Wallace D, Rabinowitz J, Lu W, Wherry J, Weiss S, Henrickson S. Impaired Lymphocyte Responses in Pediatric Sepsis Vary by Pathogen Type and are Associated with Features of Immunometabolic Dysregulation. Shock. 2022;57(6):191–199. PMCID: PMC9245144
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  • 1.
    Du J, Estrella M, Solorio-Kirpichyan K, Jeffrey P, Korennykh A. Structure of human NADK2 reveals atypical assembly and regulation of NAD kinases from animal mitochondria. Proc Natl Acad Sci U S A. 2022;119(26):e2200923119. PMCID: PMC9245612
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  • 1.
    Hansen J, Sealfon R, Menon R, Eadon M, Lake B, Steck B, Anjani K, Parikh S, Sigdel T, Zhang G, Velickovic D, Barwinska D, Alexandrov T, Dobi D, Rashmi P, Otto E, Rivera M, Rose M, Anderton C, Shapiro J, Pamreddy A, Winfree S, Xiong Y, He Y, de Boer I, Hodgin J, Barisoni L, Naik A, Sharma K, Sarwal M, Zhang K, Himmelfarb J, Rovin B, El-Achkar T, Laszik Z, He J, Dagher P, Valerius T, Jain S, Satlin L, Troyanskaya O, Kretzler M, Iyengar R, Azeloglu E, Kidney Precision Medicine Project. A reference tissue atlas for the human kidney. Sci Adv. 2022;8(23):eabn4965. PMCID: PMC9176741
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  • 1.
    Biswas S, Rust L, Wettengel J, Yusova S, Fischer M, Carson J, Johnson J, Wei L, Thode T, Kaadige M, Sharma S, Agbaria M, Bimber B, Tu T, Protzer U, Ploss A, Smedley J, Golomb G, Sacha J, Burwitz B. Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity. Nat Commun. 2022;13(1):2995. PMCID: PMC9151762
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