Lukasak B, Mitchener M, Kong L, Dul B, Lazarus C, Ramakrishnan A, Ni J, Shen L, Maze I, Muir T. TGM2-mediated histone transglutamination is dictated by steric accessibility. Proc Natl Acad Sci U S A. 2022;119(43):e2208672119. PMCID: PMC9618071

Mitchener M, Muir T. Oncohistones: Exposing the nuances and vulnerabilities of epigenetic regulation. Mol Cell. 2022;82(16):2925–2938. PMCID: PMC9482148

Dao H, Liu H, Mashtalir N, Kadoch C, Muir T. Synthesis of Oriented Hexasomes and Asymmetric Nucleosomes Using a Template Editing Process. J Am Chem Soc. 2022;144(5):2284–2291. PMCID: PMC8935522

Burton A, Hamza G, Zhang A, Muir T. Chemical biology approaches to study histone interactors. Biochem Soc Trans. 2021;49(5):2431–2441. PMCID: PMC9785950

Eeftens J, Kapoor M, Michieletto D, Brangwynne C. Polycomb condensates can promote epigenetic marks but are not required for sustained chromatin compaction. Nat Commun. 2021;12(1):5888. PMCID: PMC8497513

Mashtalir N, Dao H, Sankar A, Liu H, Corin A, Bagert J, Ge E, D’Avino A, Filipovski M, Michel B, Dann G, Muir T, Kadoch C. Chromatin landscape signals differentially dictate the activities of mSWI/SNF family complexes. Science. 2021;373(6552):306–315. PMCID: PMC8390793

Mitchener M, Muir T. Janus Bioparticles: Asymmetric Nucleosomes and Their Preparation Using Chemical Biology Approaches. Acc Chem Res. 2021;54(16):3215–3227. PMCID: PMC8411803

Hananya N, Daley S, Bagert J, Muir T. Synthesis of ADP-Ribosylated Histones Reveals Site-Specific Impacts on Chromatin Structure and Function. J Am Chem Soc. 2021;143(29):10847–10852. PMID: 34264659

Zhao S, Chuh K, Zhang B, Dul B, Thompson R, Farrelly L, Liu X, Xu N, Xue Y, Roeder R, Maze I, Muir T, Li H. Histone H3Q5 serotonylation stabilizes H3K4 methylation and potentiates its readout. Proc Natl Acad Sci U S A. 2021;118(6). PMCID: PMC8017887

Ing-Simmons E, Vaid R, Bing X, Levine M, Mannervik M, Vaquerizas J. Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning. Nat Genet. 2021;53(4):487–499. PMCID: PMC8035076

Bagert J, Muir T. Molecular Epigenetics: Chemical Biology Tools Come of Age. Annu Rev Biochem. 2021;90:287–320. PMCID: PMC8284505

Wu A, Zhi J, Tian T, Cihan A, Cevher M, Liu Z, David Y, Muir T, Roeder R, Yu M. DOT1L complex regulates transcriptional initiation in human erythroleukemic cells. Proc Natl Acad Sci U S A. 2021;118(27). PMCID: PMC8271641

Bagert J, Mitchener M, Patriotis A, Dul B, Wojcik F, Nacev B, Feng L, Allis D, Muir T. Oncohistone mutations enhance chromatin remodeling and alter cell fates. Nat Chem Biol. 2021;17(4):403–411. PMCID: PMC8174649

Leicher R, Ge E, Lin X, Reynolds M, Xie W, Walz T, Zhang B, Muir T, Liu S. Single-molecule and in silico dissection of the interaction between Polycomb repressive complex 2 and chromatin. Proc Natl Acad Sci U S A. 2020;117(48):30465–30475. PMCID: PMC7720148

McBride M, Mashtalir N, Winter E, Dao H, Filipovski M, D’Avino A, Seo H-S, Umbreit N, St Pierre R, Valencia A, Qian K, Zullow H, Jaffe J, Dhe-Paganon S, Muir T, Kadoch C. The nucleosome acidic patch and H2A ubiquitination underlie mSWI/SNF recruitment in synovial sarcoma. Nat Struct Mol Biol. 2020;27(9):836–845. PMCID: PMC7714695

Anlas A, Nelson C. Living under Strain: How Epithelia Protect Their Genomes from Repeated Stretching. Biochemistry. 2020;59(30):2761–2763. PMID: 32702973

Xu Y, Zhang Y, García-Cañaveras J, Guo L, Kan M, Yu S, Blair I, Rabinowitz J, Yang X. Chaperone-mediated autophagy regulates the pluripotency of embryonic stem cells. Science. 2020;369(6502):397–403. PMCID: PMC7939502

Murawska M, Schauer T, Matsuda A, Wilson M, Pysik T, Wojcik F, Muir T, Hiraoka Y, Straub T, Ladurner A. The Chaperone FACT and Histone H2B Ubiquitination Maintain S. pombe Genome Architecture through Genic and Subtelomeric Functions. Mol Cell. 2020;77(3):501–513.e7. PMCID: PMC7007867

Diehl K, Muir T. Chromatin as a key consumer in the metabolite economy. Nat Chem Biol. 2020;16(6):620–629. PMCID: PMC7258299

Burton A, Haugbro M, Gates L, Bagert J, Allis D, Muir T. In situ chromatin interactomics using a chemical bait and trap approach. Nat Chem. 2020;12(6):520–527. PMCID: PMC7331920

Dao H, Dul B, Dann G, Liszczak G, Muir T. A basic motif anchoring ISWI to nucleosome acidic patch regulates nucleosome spacing. Nat Chem Biol. 2020;16(2):134–142. PMCID: PMC6982587

Diehl K, Ge E, Weinberg D, Jani K, Allis D, Muir T. PRC2 engages a bivalent H3K27M-H3K27me3 dinucleosome inhibitor. Proc Natl Acad Sci U S A. 2019;116(44):22152–22157. PMCID: PMC6825254

Albig C, Wang C, Dann G, Wojcik F, Schauer T, Krause S, Maenner S, Cai W, Li Y, Girton J, Muir T, Johansen J, Johansen K, Becker P, Regnard C. JASPer controls interphase histone H3S10 phosphorylation by chromosomal kinase JIL-1 in Drosophila. Nat Commun. 2019;10(1):5343. PMCID: PMC6877644

Chen C-F, Pohl T, Chan A, Slocum J, Zakian V. Centromere RNA Is Negatively Regulated by Cbf1 and Its Unscheduled Synthesis Impacts CenH3 Binding. Genetics. 2019;213(2):465–479. PMCID: PMC6781895

Jain S, Do T, Lund P, Rashoff A, Diehl K, Cieslik M, Bajic A, Juretic N, Deshmukh S, Venneti S, Muir T, Garcia B, Jabado N, Lewis P. PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism. Nat Commun. 2019;10(1):2146. PMCID: PMC6513997

Farrelly L, Thompson R, Zhao S, Lepack A, Lyu Y, Bhanu N, Zhang B, Loh Y-H, Ramakrishnan A, Vadodaria K, Heard K, Erikson G, Nakadai T, Bastle R, Lukasak B, Zebroski H, Alenina N, Bader M, Berton O, Roeder R, Molina H, Gage F, Shen L, Garcia B, Li H, Muir T, Maze I. Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3. Nature. 2019;567(7749):535–539. PMCID: PMC6557285

Nacev B, Feng L, Bagert J, Lemiesz A, Gao J, Soshnev A, Kundra R, Schultz N, Muir T, Allis D. The expanding landscape of ’oncohistone’ mutations in human cancers. Nature. 2019;567(7749):473–478. PMCID: PMC6512987

Jani K, Jain S, Ge E, Diehl K, Lundgren S, Müller M, Lewis P, Muir T. Histone H3 tail binds a unique sensing pocket in EZH2 to activate the PRC2 methyltransferase. Proc Natl Acad Sci U S A. 2019;116(17):8295–8300. PMCID: PMC6486736

Carabetta V, Greco T, Cristea I, Dubnau D. YfmK is an N-lysine acetyltransferase that directly acetylates the histone-like protein HBsu in . Proc Natl Acad Sci U S A. 2019;116(9):3752–3757. PMCID: PMC6397556

Tabuchi T, Rechtsteiner A, Jeffers T, Egelhofer T, Murphy C, Strome S. Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis. Nat Commun. 2018;9(1):4310. PMCID: PMC6193031

Jeon J, McGinty R, Muir T, Kim J-A, Kim J. Crosstalk among Set1 complex subunits involved in H2B ubiquitylation-dependent H3K4 methylation. Nucleic Acids Res. 2018;46(21):11129–11143. PMCID: PMC6265457

O’Connell B, Adamson B, Lydeard J, Sowa M, Ciccia A, Bredemeyer A, Schlabach M, Gygi S, Elledge S, Harper W. A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. Mol Cell. 2010;40(4):645–57. PMCID: PMC3006237

Liszczak G, Diehl K, Dann G, Muir T. Acetylation blocks DNA damage-induced chromatin ADP-ribosylation. Nat Chem Biol. 2018;14(9):837–840. PMCID: PMC6505472

Bos J, Muir T. A Chemical Probe for Protein Crotonylation. J Am Chem Soc. 2018;140(14):4757–4760. PMCID: PMC6505473

Wojcik F, Dann G, Beh L, Debelouchina G, Hofmann R, Muir T. Functional crosstalk between histone H2B ubiquitylation and H2A modifications and variants. Nat Commun. 2018;9(1):1394. PMCID: PMC5895630

Jenness C, Giunta S, Müller M, Kimura H, Muir T, Funabiki H. HELLS and CDCA7 comprise a bipartite nucleosome remodeling complex defective in ICF syndrome. Proc Natl Acad Sci U S A. 2018;115(5):E876-E885. PMCID: PMC5798369

Wang X, Paucek R, Gooding A, Brown Z, Ge E, Muir T, Cech T. Molecular analysis of PRC2 recruitment to DNA in chromatin and its inhibition by RNA. Nat Struct Mol Biol. 2017;24(12):1028–1038. PMCID: PMC5771497

Oberstein A, Shenk T. Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. Proc Natl Acad Sci U S A. 2017;114(39):E8244-E8253. PMCID: PMC5625929

Dann G, Liszczak G, Bagert J, Müller M, Nguyen U, Wojcik F, Brown Z, Bos J, Panchenko T, Pihl R, Pollock S, Diehl K, Allis D, Muir T. ISWI chromatin remodellers sense nucleosome modifications to determine substrate preference. Nature. 2017;548(7669):607–611. PMCID: PMC5777669

Santos J, Josling G, Ross P, Joshi P, Orchard L, Campbell T, Schieler A, Cristea I, Llinás M. Red Blood Cell Invasion by the Malaria Parasite Is Coordinated by the PfAP2-I Transcription Factor. Cell Host Microbe. 2017;21(6):731–741.e10. PMCID: PMC5855115

Holt M, David Y, Pollock S, Tang Z, Jeon J, Kim J, Roeder R, Muir T. Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin. Proc Natl Acad Sci U S A. 2015;112(33):10365–70. PMCID: PMC4547310

Lu C, Jain S, Hoelper D, Bechet D, Molden R, Ran L, Murphy D, Venneti S, Hameed M, Pawel B, Wunder J, Dickson B, Lundgren S, Jani K, De Jay N, Papillon-Cavanagh S, Andrulis I, Sawyer S, Grynspan D, Turcotte R, Nadaf J, Fahiminiyah S, Muir T, Majewski J, Thompson C, Chi P, Garcia B, Allis D, Jabado N, Lewis P. Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape. Science. 2016;352(6287):844–9. PMCID: PMC4928577

Su X, Wellen K, Rabinowitz J. Metabolic control of methylation and acetylation. Curr Opin Chem Biol. 2016;30:52–60. PMCID: PMC4731252

Müller M, Fierz B, Bittova L, Liszczak G, Muir T. A two-state activation mechanism controls the histone methyltransferase Suv39h1. Nat Chem Biol. 2016;12(3):188–93. PMCID: PMC4876634

Zhou L, Holt M, Ohashi N, Zhao A, Müller M, Wang B, Muir T. Evidence that ubiquitylated H2B corrals hDot1L on the nucleosomal surface to induce H3K79 methylation. Nat Commun. 2016;7:10589. PMCID: PMC4740876

Arnaudo A, Link J, Garcia B. Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS Chem Biol. 2016;11(3):782–91. PMCID: PMC4844183