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Hepacivirus

  • 1.
    Brown R, Tegtmeyer B, Sheldon J, Khera T, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran F, Krey T, Ströh L, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr A, McClure P, Randall G, Baktash Y, Ploss A, Thi V, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice C, Pietschmann T. Liver-expressed and limit hepatitis C virus cross-species transmission to mice. Sci Adv. 2020;6(45). PMCID: PMC7673688
    Reference Link
  • 1.
    Berggren K, Suzuki S, Ploss A. Animal Models Used in Hepatitis C Virus Research. Int J Mol Sci. 2020;21(11). PMCID: PMC7312079
    Reference Link
  • 1.
    Ploss A, Kapoor A. Animal Models of Hepatitis C Virus Infection. Cold Spring Harb Perspect Med. 2020;10(5). PMCID: PMC7197424
    Reference Link
  • 1.
    Yau T, Hsu C, Kim T-Y, Choo S-P, Kang Y-K, Hou M-M, Numata K, Yeo W, Chopra A, Ikeda M, Kuromatsu R, Moriguchi M, Chao Y, Zhao H, Anderson J, Cruz C, Kudo M. Nivolumab in advanced hepatocellular carcinoma: Sorafenib-experienced Asian cohort analysis. J Hepatol. 2019;71(3):543–552. PMID: 31176752
    Reference Link
  • 1.
    Gaska J, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019;8. PMCID: PMC6510530
    Reference Link
  • 1.
    Gaska J, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods Mol Biol. 2019;1911:481–503. PMCID: PMC6699619
    Reference Link
  • 1.
    Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert T, Ploss A, Carbone A, Cosset F-L, Lavillette D. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism. PLoS Pathog. 2018;14(3):e1006908. PMCID: PMC5854445
    Reference Link
  • 1.
    Li D, Wang X, von Schaewen M, Tao W, Zhang Y, Heller B, Hrebikova G, Deng Q, Sun Q, Ploss A, Zhong J, Huang Z. Immunization With a Subunit Hepatitis C Virus Vaccine Elicits Pan-Genotypic Neutralizing Antibodies and Intrahepatic T-Cell Responses in Nonhuman Primates. J Infect Dis. 2017;215(12):1824–1831. PMCID: PMC5853543
    Reference Link
  • 1.
    von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz J, Gerold G, Suerbaum S, Rice C, Meuleman P, Pietschmann T, Ploss A. Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. mBio. 2016;7(6). PMCID: PMC5101358
    Reference Link
  • 1.
    Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, Ploss A. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017;91(4). PMCID: PMC5286898
    Reference Link
  • 1.
    Li D, von Schaewen M, Wang X, Tao W, Zhang Y, Li L, Heller B, Hrebikova G, Deng Q, Ploss A, Zhong J, Huang Z. Altered Glycosylation Patterns Increase Immunogenicity of a Subunit Hepatitis C Virus Vaccine, Inducing Neutralizing Antibodies Which Confer Protection in Mice. J Virol. 2016;90(23):10486–10498. PMCID: PMC5110194
    Reference Link
  • 1.
    Perin P, Haid S, Brown R, Doerrbecker J, Schulze K, Zeilinger C, von Schaewen M, Heller B, Vercauteren K, Luxenburger E, Baktash Y, Vondran F, Speerstra S, Awadh A, Mukhtarov F, Schang L, Kirschning A, Müller R, Guzman C, Kaderali L, Randall G, Meuleman P, Ploss A, Pietschmann T. Flunarizine prevents hepatitis C virus membrane fusion in a genotype-dependent manner by targeting the potential fusion peptide within E1. Hepatology. 2016;63(1):49–62. PMCID: PMC4688136
    Reference Link
  • 1.
    Scull M, Shi C, de Jong Y, Gerold G, Ries M, von Schaewen M, Donovan B, Labitt R, Horwitz J, Gaska J, Hrebikova G, Xiao J, Flatley B, Fung C, Chiriboga L, Walker C, Evans D, Rice C, Ploss A. Hepatitis C virus infects rhesus macaque hepatocytes and simianized mice. Hepatology. 2015;62(1):57–67. PMCID: PMC4482775
    Reference Link

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