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Glycolysis

  • 1.
    Bartman C, Weilandt D, Shen Y, Lee W, Han Y, TeSlaa T, Jankowski C, Samarah L, Park N, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Heiden M, Herranz D, Guo J, Kang Y, Rabinowitz J. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. 2023;614(7947):349–357. PMID: 36725930
    Reference Link
  • 1.
    Wang L, Xing X, Zeng X, Jackson R, TeSlaa T, Al-Dalahmah O, Samarah L, Goodwin K, Yang L, McReynolds M, Li X, Wolff J, Rabinowitz J, Davidson S. Spatially resolved isotope tracing reveals tissue metabolic activity. Nat Methods. 2022;19(2):223–230. PMID: 35132243
    Reference Link
  • 1.
    TeSlaa T, Bartman C, Jankowski C, Zhang Z, Xu X, Xing X, Wang L, Lu W, Hui S, Rabinowitz J. The Source of Glycolytic Intermediates in Mammalian Tissues. Cell Metab. 2021;33(2):367–378.e5. PMCID: PMC8088818
    Reference Link
  • 1.
    Rabinowitz J, Enerbäck S. Lactate: the ugly duckling of energy metabolism. Nat Metab. 2020;2(7):566–571. PMCID: PMC7983055
    Reference Link
  • 1.
    Ghergurovich J, García-Cañaveras J, Wang J, Schmidt E, Zhang Z, TeSlaa T, Patel H, Chen L, Britt E, Piqueras-Nebot M, Gomez-Cabrera M, Lahoz A, Fan J, Beier U, Kim H, Rabinowitz J. A small molecule G6PD inhibitor reveals immune dependence on pentose phosphate pathway. Nat Chem Biol. 2020;16(7):731–739. PMCID: PMC7311271
    Reference Link
  • 1.
    Park J, Tanner L, Wei M, Khana D, Jacobson T, Zhang Z, Rubin S, Li S, Higgins M, Stevenson D, Amador-Noguez D, Rabinowitz J. Near-equilibrium glycolysis supports metabolic homeostasis and energy yield. Nat Chem Biol. 2019;15(10):1001–1008. PMID: 31548693
    Reference Link
  • 1.
    García-Cañaveras J, Chen L, Rabinowitz J. The Tumor Metabolic Microenvironment: Lessons from Lactate. Cancer Res. 2019;79(13):3155–3162. PMCID: PMC6606343
    Reference Link
  • 1.
    Tanner L, Goglia A, Wei M, Sehgal T, Parsons L, Park J, White E, Toettcher J, Rabinowitz J. Four Key Steps Control Glycolytic Flux in Mammalian Cells. Cell Syst. 2018;7(1):49–62.e8. PMCID: PMC6062487
    Reference Link
  • 1.
    Jang C, Chen L, Rabinowitz J. Metabolomics and Isotope Tracing. Cell. 2018;173(4):822–837. PMCID: PMC6034115
    Reference Link
  • 1.
    Hui S, Ghergurovich J, Morscher R, Jang C, Teng X, Lu W, Esparza L, Reya T, Guo J, White E, Rabinowitz J. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017;551(7678):115–118. PMCID: PMC5898814
    Reference Link
  • 1.
    Hackett S, Zanotelli V, Xu W, Goya J, Park J, Perlman D, Gibney P, Botstein D, Storey J, Rabinowitz J. Systems-level analysis of mechanisms regulating yeast metabolic flux. Science. 2016;354(6311). PMCID: PMC5414049
    Reference Link
  • 1.
    Hwang J, Purdy J, Wu K, Rabinowitz J, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proc Natl Acad Sci U S A. 2014;111(52):E5706–15. PMCID: PMC4284536
    Reference Link

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