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Genome, Human

  • 1.
    Hussmann J, Ling J, Ravisankar P, Yan J, Cirincione A, Xu A, Simpson D, Yang D, Bothmer A, Cotta-Ramusino C, Weissman J, Adamson B. Mapping the genetic landscape of DNA double-strand break repair. Cell. 2021;184(22):5653–5669.e25. PMCID: PMC9074467
    Reference Link
  • 1.
    Chen P, Hussmann J, Yan J, Knipping F, Ravisankar P, Chen P-F, Chen C, Nelson J, Newby G, Sahin M, Osborn M, Weissman J, Adamson B, Liu D. Enhanced prime editing systems by manipulating cellular determinants of editing outcomes. Cell. 2021;184(22):5635–5652.e29. PMCID: PMC8584034
    Reference Link
  • 1.
    Wong A, Sealfon R, Theesfeld C, Troyanskaya O. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021;22(12):774–790. PMCID: 6786975
    Reference Link
  • 1.
    Omenn G, Lane L, Overall C, Cristea I, Corrales F, Lindskog C, Paik Y-K, Van Eyk J, Liu S, Pennington S, Snyder M, Baker M, Bandeira N, Aebersold R, Moritz R, Deutsch E. Research on the Human Proteome Reaches a Major Milestone: >90% of Predicted Human Proteins Now Credibly Detected, According to the HUPO Human Proteome Project. J Proteome Res. 2020;19(12):4735–4746. PMCID: PMC7718309
    Reference Link
  • 1.
    Cabreros I, Storey J. A Likelihood-Free Estimator of Population Structure Bridging Admixture Models and Principal Components Analysis. Genetics. 2019;212(4):1009–1029. PMCID: PMC6707457
    Reference Link
  • 1.
    Valencia A, Collings C, Dao H, St Pierre R, Cheng Y-C, Huang J, Sun Z-Y, Seo H-S, Mashtalir N, Comstock D, Bolonduro O, Vangos N, Yeoh Z, Dornon M, Hermawan C, Barrett L, Dhe-Paganon S, Woolf C, Muir T, Kadoch C. Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling. Cell. 2019;179(6):1342–1356.e23. PMCID: PMC7175411
    Reference Link
  • 1.
    Zhou J, Park C, Theesfeld C, Wong A, Yuan Y, Scheckel C, Fak J, Funk J, Yao K, Tajima Y, Packer A, Darnell R, Troyanskaya O. Whole-genome deep-learning analysis identifies contribution of noncoding mutations to autism risk. Nat Genet. 2019;51(6):973–980. PMCID: PMC6758908
    Reference Link
  • 1.
    Shin Y, Chang Y-C, Lee D, Berry J, Sanders D, Ronceray P, Wingreen N, Haataja M, Brangwynne C. Liquid Nuclear Condensates Mechanically Sense and Restructure the Genome. Cell. 2018;175(6):1481–1491.e13. PMCID: PMC6724728
    Reference Link
  • 1.
    O’Connell B, Adamson B, Lydeard J, Sowa M, Ciccia A, Bredemeyer A, Schlabach M, Gygi S, Elledge S, Harper W. A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability. Mol Cell. 2010;40(4):645–57. PMCID: PMC3006237
    Reference Link
  • 1.
    Adamson B, Smogorzewska A, Sigoillot F, King R, Elledge S. A genome-wide homologous recombination screen identifies the RNA-binding protein RBMX as a component of the DNA-damage response. Nat Cell Biol. 2012;14(3):318–28. PMCID: PMC3290715
    Reference Link
  • 1.
    Gilbert L, Horlbeck M, Adamson B, Villalta J, Chen Y, Whitehead E, Guimaraes C, Panning B, Ploegh H, Bassik M, Qi L, Kampmann M, Weissman J. Genome-Scale CRISPR-Mediated Control of Gene Repression and Activation. Cell. 2014;159(3):647–61. PMCID: PMC4253859
    Reference Link
  • 1.
    Aebersold R, Agar J, Amster J, Baker M, Bertozzi C, Boja E, Costello C, Cravatt B, Fenselau C, Garcia B, Ge Y, Gunawardena J, Hendrickson R, Hergenrother P, Huber C, Ivanov A, Jensen O, Jewett M, Kelleher N, Kiessling L, Krogan N, Larsen M, Loo J, Loo R, Lundberg E, MacCoss M, Mallick P, Mootha V, Mrksich M, Muir T, Patrie S, Pesavento J, Pitteri S, Rodriguez H, Saghatelian A, Sandoval W, Schlüter H, Sechi S, Slavoff S, Smith L, Snyder M, Thomas P, Uhlén M, Van Eyk J, Vidal M, Walt D, White F, Williams E, Wohlschlager T, Wysocki V, Yates N, Young N, Zhang B. How many human proteoforms are there?. Nat Chem Biol. 2018;14(3):206–214. PMCID: PMC5837046
    Reference Link
  • 1.
    Zhou J, Troyanskaya O. Predicting effects of noncoding variants with deep learning-based sequence model. Nat Methods. 2015;12(10):931–4. PMCID: PMC4768299
    Reference Link

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