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Genetic Variation

  • 1.
    Barnes T, Karlin M, vonHoldt B, Adams J, Waits L, Hinton J, Henderson J, Brzeski K. Genetic diversity and family groups detected in a coyote population with red wolf ancestry on Galveston Island, Texas. BMC Ecol Evol. 2022;22(1):134. PMCID: PMC9664737
    Reference Link
  • 1.
    Mashruwala A, Qin B, Bassler B. Quorum-sensing- and type VI secretion-mediated spatiotemporal cell death drives genetic diversity in Vibrio cholerae. Cell. 2022;185(21):3966–3979.e13. PMCID: PMC9623500
    Reference Link
  • 1.
    Tamura T, Zhang J, Madan V, Biswas A, Schwoerer M, Cafiero T, Heller B, Wang W, Ploss A. Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4. Emerg Microbes Infect. 2022;11(1):227–239. PMCID: PMC8745371
    Reference Link
  • 1.
    Matthews B, Dudchenko O, Kingan S, Koren S, Antoshechkin I, Crawford J, Glassford W, Herre M, Redmond S, Rose N, Weedall G, Wu Y, Batra S, Brito-Sierra C, Buckingham S, Campbell C, Chan S, Cox E, Evans B, Fansiri T, Filipović I, Fontaine A, Gloria-Soria A, Hall R, Joardar V, Jones A, Kay R, Kodali V, Lee J, Lycett G, Mitchell S, Muehling J, Murphy M, Omer A, Partridge F, Peluso P, Aiden A, Ramasamy V, Rašić G, Roy S, Saavedra-Rodriguez K, Sharan S, Sharma A, Smith M, Turner J, Weakley A, Zhao Z, Akbari O, Black W, Cao H, Darby A, Hill C, Johnston S, Murphy T, Raikhel A, Sattelle D, Sharakhov I, White B, Zhao L, Aiden E, Mann R, Lambrechts L, Powell J, Sharakhova M, Tu Z, Robertson H, McBride C, Hastie A, Korlach J, Neafsey D, Phillippy A, Vosshall L. Improved reference genome of Aedes aegypti informs arbovirus vector control. Nature. 2018;563(7732):501–507. PMCID: PMC6421076
    Reference Link
  • 1.
    Wong A, Sealfon R, Theesfeld C, Troyanskaya O. Decoding disease: from genomes to networks to phenotypes. Nat Rev Genet. 2021;22(12):774–790. PMCID: 6786975
    Reference Link
  • 1.
    Taron U, Salado I, Escobar-Rodríguez M, Westbury M, Butschkau S, Paijmans J, vonHoldt B, Hofreiter M, Leonard J. A sliver of the past: The decimation of the genetic diversity of the Mexican wolf. Mol Ecol. 2021;30(23):6340–6354. PMID: 34161633
    Reference Link
  • 1.
    Richter F, Morton S, Kim S, Kitaygorodsky A, Wasson L, Chen K, Zhou J, Qi H, Patel N, DePalma S, Parfenov M, Homsy J, Gorham J, Manheimer K, Velinder M, Farrell A, Marth G, Schadt E, Kaltman J, Newburger J, Giardini A, Goldmuntz E, Brueckner M, Kim R, Porter G, Bernstein D, Chung W, Srivastava D, Tristani-Firouzi M, Troyanskaya O, Dickel D, Shen Y, Seidman J, Seidman C, Gelb B. Genomic analyses implicate noncoding de novo variants in congenital heart disease. Nat Genet. 2020;52(8):769–777. PMCID: PMC7415662
    Reference Link
  • 1.
    Aardema M, vonHoldt B, Fritz M, Davis S. Global evaluation of taxonomic relationships and admixture within the Culex pipiens complex of mosquitoes. Parasit Vectors. 2020;13(1):8. PMCID: PMC6950815
    Reference Link
  • 1.
    Benson K, Hu W, Weller A, Bennett A, Chen E, Khetarpal S, Yoshino S, Bone W, Wang L, Rabinowitz J, Voight B, Soccio R. Natural human genetic variation determines basal and inducible expression of , an obesity-associated gene. Proc Natl Acad Sci U S A. 2019;116(46):23232–23242. PMCID: PMC6859347
    Reference Link
  • 1.
    Gaska J, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019;8. PMCID: PMC6510530
    Reference Link
  • 1.
    Cadoff E, Sheffer R, Wientroub S, Ovadia D, Meiner V, Schwarzbauer J. Mechanistic insights into the cellular effects of a novel FN1 variant associated with a spondylometaphyseal dysplasia. Clin Genet. 2018;94(5):429–437. PMCID: PMC6175647
    Reference Link
  • 1.
    Robinson J, Del Vecchyo D, Fan Z, Kim B, vonHoldt B, Marsden C, Lohmueller K, Wayne R. Genomic Flatlining in the Endangered Island Fox. Curr Biol. 2016;26(9):1183–9. PMID: 27112291
    Reference Link
  • 1.
    vonHoldt B, Shuldiner E, Koch I, Kartzinel R, Hogan A, Brubaker L, Wanser S, Stahler D, Wynne C, Ostrander E, Sinsheimer J, Udell M. Structural variants in genes associated with human Williams-Beuren syndrome underlie stereotypical hypersociability in domestic dogs. Sci Adv. 2017;3(7):e1700398. PMCID: PMC5517105
    Reference Link
  • 1.
    Hao W, Song M, Storey J. Probabilistic models of genetic variation in structured populations applied to global human studies. Bioinformatics. 2016;32(5):713–21. PMCID: PMC4795615
    Reference Link
  • 1.
    Rajeshkumar N, Yabuuchi S, Pai S, De Oliveira E, Kamphorst J, Rabinowitz J, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang C. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017;23(18):5639–5647. PMCID: PMC6540110
    Reference Link
  • 1.
    McCulloch K, Yuan F, Zhen Y, Aardema M, Smith G, Llorente-Bousquets J, Andolfatto P, Briscoe A. Sexual Dimorphism and Retinal Mosaic Diversification following the Evolution of a Violet Receptor in Butterflies. Mol Biol Evol. 2017;34(9):2271–2284. PMID: 28505307
    Reference Link
  • 1.
    Guo J, Teng X, Laddha S, Ma S, Van Nostrand S, Yang Y, Khor S, Chan C, Rabinowitz J, White E. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes Dev. 2016;30(15):1704–17. PMCID: PMC5002976
    Reference Link
  • 1.
    Ghosh R, Bloom J, Mohammadi A, Schumer M, Andolfatto P, Ryu W, Kruglyak L. Genetics of Intraspecies Variation in Avoidance Behavior Induced by a Thermal Stimulus in Caenorhabditis elegans. Genetics. 2015;200(4):1327–39. PMCID: PMC4574258
    Reference Link
  • 1.
    Elyashiv E, Sattath S, Hu T, Strutsovsky A, McVicker G, Andolfatto P, Coop G, Sella G. A Genomic Map of the Effects of Linked Selection in Drosophila. PLoS Genet. 2016;12(8):e1006130. PMCID: PMC4990265
    Reference Link
  • 1.
    Verhoeven K, vonHoldt B, Sork V. Epigenetics in ecology and evolution: what we know and what we need to know. Mol Ecol. 2016;25(8):1631–8. PMID: 26994410
    Reference Link
  • 1.
    Chung N, Storey J. Statistical significance of variables driving systematic variation in high-dimensional data. Bioinformatics. 2015;31(4):545–54. PMCID: PMC4325543
    Reference Link
  • 1.
    Rogers R, Cridland J, Shao L, Hu T, Andolfatto P, Thornton K. Landscape of standing variation for tandem duplications in Drosophila yakuba and Drosophila simulans. Mol Biol Evol. 2014;31(7):1750–66. PMCID: PMC4069613
    Reference Link
  • 1.
    Schumer M, Cui R, Rosenthal G, Andolfatto P. Reproductive isolation of hybrid populations driven by genetic incompatibilities. PLoS Genet. 2015;11(3):e1005041. PMCID: PMC4359097
    Reference Link
  • 1.
    Rogers R, Cridland J, Shao L, Hu T, Andolfatto P, Thornton K. Tandem Duplications and the Limits of Natural Selection in Drosophila yakuba and Drosophila simulans. PLoS One. 2015;10(7):e0132184. PMCID: PMC4503668
    Reference Link
  • 1.
    Arthur B, Sunayama-Morita T, Coen P, Murthy M, Stern D. Multi-channel acoustic recording and automated analysis of Drosophila courtship songs. BMC Biol. 2013;11:11. PMCID: PMC3599446
    Reference Link

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