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Gene Knockdown Techniques

  • 1.
    Wilke A, Doebele C, Zindel A, Lee K, Rieke S, Ceribelli M, Comoglio F, Phelan J, Wang J, Pikman Y, Jahn D, Häupl B, Schneider C, Scheich S, Tosto F, Bohnenberger H, Stauder P, Schnütgen F, Slabicki M, Coulibaly Z, Wolf S, Bojarczuk K, Chapuy B, Brandts C, Stroebel P, Lewis C, Engelke M, Xu X, Kim H, Dang T, Schmitz R, Hodson D, Stegmaier K, Urlaub H, Serve H, Schmitt C, Kreuz F, Knittel G, Rabinowitz J, Reinhardt H, Heiden M, Thomas C, Staudt L, Zenz T, Oellerich T. SHMT2 inhibition disrupts the TCF3 transcriptional survival program in Burkitt lymphoma. Blood. 2022;139(4):538–553. PMCID: PMC8938936
    Reference Link
  • 1.
    Nogalski M, Shenk T. HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement. Proc Natl Acad Sci U S A. 2020;117(50):31891–31901. PMCID: PMC7749351
    Reference Link
  • 1.
    Ghergurovich J, Esposito M, Chen Z, Wang J, Bhatt V, Lan T, White E, Kang Y, Guo J, Rabinowitz J. Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. Cancer Res. 2020;80(18):3820–3829. PMCID: PMC7501231
    Reference Link
  • 1.
    Grimes D, Patterson V, Luna-Arvizu G, Schottenfeld-Roames J, Irons Z, Burdine R. Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Dev Biol. 2020;459(2):79–86. PMID: 31758943
    Reference Link
  • 1.
    Chen S, Shenk T, Nogalski M. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019;116(38):18971–18982. PMCID: PMC6754545
    Reference Link
  • 1.
    Dixit A, Parnas O, Li B, Chen J, Fulco C, Jerby-Arnon L, Marjanovic N, Dionne D, Burks T, Raychowdhury R, Adamson B, Norman T, Lander E, Weissman J, Friedman N, Regev A iv. Perturb-Seq: Dissecting Molecular Circuits with Scalable Single-Cell RNA Profiling of Pooled Genetic Screens. Cell. 2016;167(7):1853–1866.e17. PMCID: PMC5181115
    Reference Link
  • 1.
    Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis G, Schuchter L, Xu W, Amaravadi R, Xiao M, Sadek N, Krepler C, Herlyn M, Freeman G, Rabinowitz J, Ertl H. Enhancing CD8 T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32(3):377–391.e9. PMCID: PMC5751418
    Reference Link
  • 1.
    Hong S, Zhou W, Fang B, Lu W, Loro E, Damle M, Ding G, Jager J, Zhang S, Zhang Y, Feng D, Chu Q, Dill B, Molina H, Khurana T, Rabinowitz J, Lazar M, Sun Z. Dissociation of muscle insulin sensitivity from exercise endurance in mice by HDAC3 depletion. Nat Med. 2017;23(2):223–234. PMCID: PMC5540654
    Reference Link
  • 1.
    Alesi G, Jin L, Li D, Magliocca K, Kang Y, Chen Z, Shin D, Khuri F, Kang S. RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis. Oncogene. 2016;35(41):5412–5421. PMCID: PMC5226067
    Reference Link
  • 1.
    Budayeva H, Cristea I. Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking. Mol Cell Proteomics. 2016;15(10):3107–3125. PMCID: PMC5054338
    Reference Link
  • 1.
    Viktorovskaya O, Greco T, Cristea I, Thompson S. Identification of RNA Binding Proteins Associated with Dengue Virus RNA in Infected Cells Reveals Temporally Distinct Host Factor Requirements. PLoS Negl Trop Dis. 2016;10(8):e0004921. PMCID: PMC4996428
    Reference Link
  • 1.
    Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12(5):345–52. PMCID: PMC4891982
    Reference Link
  • 1.
    Chahal J, Flint S. The p53 protein does not facilitate adenovirus type 5 replication in normal human cells. J Virol. 2013;87(10):6044–6. PMCID: PMC3648133
    Reference Link

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