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Gene Expression Regulation, Developmental

  • 1.
    Treen N, Chavarria E, Weaver C, Brangwynne C, Levine M. An FGF timer for zygotic genome activation. Genes Dev. 2023;37(3-4):80–85. PMCID: PMC10069452
    Reference Link
  • 1.
    Colonnetta M, Schedl P, Deshpande G. Germline/soma distinction in embryos requires regulators of zygotic genome activation. Elife. 2023;12. PMCID: PMC9812407
    Reference Link
  • 1.
    Menon T, Burdine R. A twist in Pitx2 regulation of gut looping. Dev Cell. 2022;57(21):2445–2446. PMID: 36347237
    Reference Link
  • 1.
    Voortman L, Anderson C, Urban E, Yuan L, Tran S, Neuhaus-Follini A, Derrick J, Gregor T, Johnston R. Temporally dynamic antagonism between transcription and chromatin compaction controls stochastic photoreceptor specification in flies. Dev Cell. 2022;57(15):1817–1832.e5. PMCID: PMC9378680
    Reference Link
  • 1.
    Devenport D. A squash and a squeeze. Elife. 2022;11. PMCID: PMC9246364
    Reference Link
  • 1.
    Levo M, Raimundo J, Bing X, Sisco Z, Batut P, Ryabichko S, Gregor T, Levine M. Transcriptional coupling of distant regulatory genes in living embryos. Nature. 2022;605(7911):754–760. PMCID: PMC9886134
    Reference Link
  • 1.
    Keenan S, Avdeeva M, Yang L, Alber D, Wieschaus E, Shvartsman S. Dynamics of endoderm specification. Proc Natl Acad Sci U S A. 2022;119(15):e2112892119. PMCID: PMC9169638
    Reference Link
  • 1.
    Singh A, Wu P, Ryabichko S, Raimundo J, Swan M, Wieschaus E, Gregor T, Toettcher J. Optogenetic control of the Bicoid morphogen reveals fast and slow modes of gap gene regulation. Cell Rep. 2022;38(12):110543. PMCID: PMC9019726
    Reference Link
  • 1.
    Batut P, Bing X, Sisco Z, Raimundo J, Levo M, Levine M. Genome organization controls transcriptional dynamics during development. Science. 2022;375(6580):566–570. PMID: 35113722
    Reference Link
  • 1.
    Chacha P, Horie R, Kusakabe T, Sasakura Y, Singh M, Horie T, Levine M. Neuronal identities derived by misexpression of the POU IV sensory determinant in a protovertebrate. Proc Natl Acad Sci U S A. 2022;119(4). PMCID: PMC8794889
    Reference Link
  • 1.
    Colonnetta M, Abrahante J, Schedl P, Gohl D, Deshpande G. CLAMP regulates zygotic genome activation in Drosophila embryos. Genetics. 2021;219(2). PMCID: PMC8633140
    Reference Link
  • 1.
    Huang S-K, Whitney P, Dutta S, Shvartsman S, Rushlow C. Spatial organization of transcribing loci during early genome activation in Drosophila. Curr Biol. 2021;31(22):5102–5110.e5. PMCID: PMC8612988
    Reference Link
  • 1.
    Maerker M, Getwan M, Dowdle M, McSheene J, Gonzalez V, Pelliccia J, Hamilton D, Yartseva V, Vejnar C, Tingler M, Minegishi K, Vick P, Giraldez A, Hamada H, Burdine R, Sheets M, Blum M, Schweickert A. Bicc1 and Dicer regulate left-right patterning through post-transcriptional control of the Nodal inhibitor Dand5. Nat Commun. 2021;12(1):5482. PMCID: PMC8446035
    Reference Link
  • 1.
    Lindström N, Sealfon R, Chen X, Parvez R, Ransick A, Brandine G, Guo J, Hill B, Tran T, Kim A, Zhou J, Tadych A, Watters A, Wong A, Lovero E, Grubbs B, Thornton M, McMahon J, Smith A, Ruffins S, Armit C, Troyanskaya O, McMahon A. Spatial transcriptional mapping of the human nephrogenic program. Dev Cell. 2021;56(16):2381–2398.e6. PMCID: PMC8396064
    Reference Link
  • 1.
    Postika N, Schedl P, Georgiev P, Kyrchanova O. Redundant enhancers in the iab-5 domain cooperatively activate Abd-B in the A5 and A6 abdominal segments of Drosophila. Development. 2021;148(19). PMCID: PMC8497775
    Reference Link
  • 1.
    Ing-Simmons E, Vaid R, Bing X, Levine M, Mannervik M, Vaquerizas J. Independence of chromatin conformation and gene regulation during Drosophila dorsoventral patterning. Nat Genet. 2021;53(4):487–499. PMCID: PMC8035076
    Reference Link
  • 1.
    Patel A, Zhang L, Keenan S, Rushlow C, Fradin C, Shvartsman S. Capicua is a fast-acting transcriptional brake. Curr Biol. 2021;31(16):3639–3647.e5. PMCID: PMC8612007
    Reference Link
  • 1.
    Treen N, Shimobayashi S, Eeftens J, Brangwynne C, Levine M. Properties of repression condensates in living Ciona embryos. Nat Commun. 2021;12(1):1561. PMCID: PMC7946874
    Reference Link
  • 1.
    Chen H, Gregor T. Using RNA Tags for Multicolor Live Imaging of Chromatin Loci and Transcription in Drosophila Embryos. Methods Mol Biol. 2020;2166:373–384. PMCID: PMC8130451
    Reference Link
  • 1.
    Johnson H, Djabrayan N, Shvartsman S, Toettcher J. Optogenetic Rescue of a Patterning Mutant. Curr Biol. 2020;30(17):3414–3424.e3. PMCID: PMC7730203
    Reference Link
  • 1.
    Merkle J, Wittes J, Schüpbach T. Signaling between somatic follicle cells and the germline patterns the egg and embryo of Drosophila. Curr Top Dev Biol. 2020;140:55–86. PMID: 32591083
    Reference Link
  • 1.
    Cao W, Kabelitz S, Gupta M, Yeung E, Lin S, Rammelt C, Ihling C, Pekovic F, Low T, Siddiqui N, Cheng M, Angers S, Smibert C, Wühr M, Wahle E, Lipshitz H. Precise Temporal Regulation of Post-transcriptional Repressors Is Required for an Orderly Drosophila Maternal-to-Zygotic Transition. Cell Rep. 2020;31(12):107783. PMCID: PMC7372737
    Reference Link
  • 1.
    Dutta S, Djabrayan N, Smits C, Rowley C, Shvartsman S. Excess dNTPs Trigger Oscillatory Surface Flow in the Early Drosophila Embryo. Biophys J. 2020;118(10):2349–2353. PMCID: PMC7231883
    Reference Link
  • 1.
    Keenan S, Blythe S, Marmion R, Djabrayan N, Wieschaus E, Shvartsman S. Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. Dev Cell. 2020;52(6):794–801.e4. PMCID: PMC7161736
    Reference Link
  • 1.
    Smits C, Shvartsman S. The design and logic of terminal patterning in Drosophila. Curr Top Dev Biol. 2020;137:193–217. PMID: 32143743
    Reference Link
  • 1.
    Paul S, Yang L, Mattingly H, Goyal Y, Shvartsman S, Veraksa A. Activation-induced substrate engagement in ERK signaling. Mol Biol Cell. 2020;31(4):235–243. PMCID: PMC7183763
    Reference Link
  • 1.
    Schüpbach T. Genetic Screens to Analyze Pattern Formation of Egg and Embryo in : A Personal History. Annu Rev Genet. 2019;53:1–18. PMID: 31794267
    Reference Link
  • 1.
    Grimes D, Patterson V, Luna-Arvizu G, Schottenfeld-Roames J, Irons Z, Burdine R. Left-right asymmetric heart jogging increases the robustness of dextral heart looping in zebrafish. Dev Biol. 2020;459(2):79–86. PMID: 31758943
    Reference Link
  • 1.
    Goodwin K, Mao S, Guyomar T, Miller E, Radisky D, Košmrlj A, Nelson C. Smooth muscle differentiation shapes domain branches during mouse lung development. Development. 2019;146(22). PMCID: PMC6899029
    Reference Link
  • 1.
    Zhou J, Schor I, Yao V, Theesfeld C, Marco-Ferreres R, Tadych A, Furlong E, Troyanskaya O. Accurate genome-wide predictions of spatio-temporal gene expression during embryonic development. PLoS Genet. 2019;15(9):e1008382. PMCID: PMC6779412
    Reference Link
  • 1.
    Chan M, Smith Z, Grosswendt S, Kretzmer H, Norman T, Adamson B, Jost M, Quinn J, Yang D, Jones M, Khodaverdian A, Yosef N, Meissner A, Weissman J. Molecular recording of mammalian embryogenesis. Nature. 2019;570(7759):77–82. PMCID: PMC7229772
    Reference Link
  • 1.
    Bialistoky T, Manry D, Smith P, Ng C, Kim Y, Zamir S, Moyal V, Kalifa R, Schedl P, Gerlitz O, Deshpande G. Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in . Development. 2019;146(10). PMCID: PMC6550021
    Reference Link
  • 1.
    Johnson H, Toettcher J. Signaling Dynamics Control Cell Fate in the Early Drosophila Embryo. Dev Cell. 2019;48(3):361–370.e3. PMCID: PMC6394837
    Reference Link
  • 1.
    Petkova M, Tkačik G, Bialek W, Wieschaus E, Gregor T. Optimal Decoding of Cellular Identities in a Genetic Network. Cell. 2019;176(4):844–855.e15. PMCID: PMC6526179
    Reference Link
  • 1.
    Wittes J, Schüpbach T. A Gene Expression Screen in Identifies Novel JAK/STAT and EGFR Targets During Oogenesis. G3 (Bethesda). 2019;9(1):47–60. PMCID: PMC6325903
    Reference Link
  • 1.
    Zoller B, Little S, Gregor T. Diverse Spatial Expression Patterns Emerge from Unified Kinetics of Transcriptional Bursting. Cell. 2018;175(3):835–847.e25. PMCID: PMC6779125
    Reference Link
  • 1.
    Patel A, Shvartsman S. Outstanding questions in developmental ERK signaling. Development. 2018;145(14). PMCID: PMC6078328
    Reference Link
  • 1.
    Goyal Y, Schüpbach T, Shvartsman S. A quantitative model of developmental RTK signaling. Dev Biol. 2018;442(1):80–86. PMCID: PMC6501586
    Reference Link
  • 1.
    Fedotova A, Aoki T, Rossier M, Mishra R, Clendinen C, Kyrchanova O, Wolle D, Bonchuk A, Maeda R, Mutero A, Cleard F, Mogila V, Karch F, Georgiev P, Schedl P. The BEN Domain Protein Insensitive Binds to the Chromatin Boundary To Establish Proper Segmental Identity in . Genetics. 2018;210(2):573–585. PMCID: PMC6216583
    Reference Link
  • 1.
    Chen H, Levo M, Barinov L, Fujioka M, Jaynes J, Gregor T. Dynamic interplay between enhancer-promoter topology and gene activity. Nat Genet. 2018;50(9):1296–1303. PMCID: PMC6119122
    Reference Link
  • 1.
    Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes D, Suzuki M, Burdine R, Cong F, Koo B-K, Clevers H, Stévant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A. ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling. Proc Natl Acad Sci U S A. 2018;115(21):5474–5479. PMCID: PMC6003506
    Reference Link
  • 1.
    Johnson H, Toettcher J. Illuminating developmental biology with cellular optogenetics. Curr Opin Biotechnol. 2018;52:42–48. PMCID: PMC6082700
    Reference Link
  • 1.
    Hasley A, Chavez S, Danilchik M, Wühr M, Pelegri F. Vertebrate Embryonic Cleavage Pattern Determination. Adv Exp Med Biol. 2017;953:117–171. PMCID: PMC6500441
    Reference Link
  • 1.
    Hannon C, Blythe S, Wieschaus E. Concentration dependent chromatin states induced by the bicoid morphogen gradient. Elife. 2017;6. PMCID: PMC5624782
    Reference Link
  • 1.
    Kyrchanova O, Zolotarev N, Mogila V, Maksimenko O, Schedl P, Georgiev P. Architectural protein Pita cooperates with dCTCF in organization of functional boundaries in Bithorax complex. Development. 2017;144(14):2663–2672. PMCID: PMC5536930
    Reference Link
  • 1.
    Pritykin Y, Brito T, Schüpbach T, Singh M, Pane A. Integrative analysis unveils new functions for the Cutoff protein in noncoding RNA biogenesis and gene regulation. RNA. 2017;23(7):1097–1109. PMCID: PMC5473144
    Reference Link
  • 1.
    Rogers W, Goyal Y, Yamaya K, Shvartsman S, Levine M. Uncoupling neurogenic gene networks in the embryo. Genes Dev. 2017;31(7):634–638. PMCID: PMC5411704
    Reference Link
  • 1.
    Deshpande G, Barr J, Gerlitz O, Lebedeva L, Shidlovskii Y ii, Schedl P. Cells on the move: Modulation of guidance cues during germ cell migration. Fly (Austin). 2017;11(3):200–207. PMCID: PMC5552272
    Reference Link
  • 1.
    Schüpbach T. The Complexities and Unexpected Insights of Developmental Genetic Analysis. Curr Top Dev Biol. 2016;117:319–30. PMID: 26969986
    Reference Link
  • 1.
    Bonchuk A, Maksimenko O, Kyrchanova O, Ivlieva T, Mogila V, Deshpande G, Wolle D, Schedl P, Georgiev P. Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster. BMC Biol. 2015;13:63. PMCID: PMC4528719
    Reference Link

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