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Gene Deletion

  • 1.
    Postika N, Schedl P, Georgiev P, Kyrchanova O. Mapping of functional elements of the Fab-6 boundary involved in the regulation of the Abd-B hox gene in Drosophila melanogaster. Sci Rep. 2021;11(1):4156. PMCID: PMC7892861
    Reference Link
  • 1.
    Guan D, Xiong Y, Trinh T, Xiao Y, Hu W, Jiang C, Dierickx P, Jang C, Rabinowitz J, Lazar M. The hepatocyte clock and feeding control chronophysiology of multiple liver cell types. Science. 2020;369(6509):1388–1394. PMCID: PMC7849028
    Reference Link
  • 1.
    Kuroda K, Hammer S, Watanabe Y, López J, Fink G, Stephanopoulos G, Ueda M, Avalos J. Critical Roles of the Pentose Phosphate Pathway and GLN3 in Isobutanol-Specific Tolerance in Yeast. Cell Syst. 2019;9(6):534–547.e5. PMID: 31734159
    Reference Link
  • 1.
    Wong C, Tang L, Davidson C, Vosburgh E, Chen W, Foran D, Notterman D, Levine A, Xu E. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death Differ. 2020;27(1):269–283. PMCID: PMC7206057
    Reference Link
  • 1.
    Hart E, Gupta M, Wühr M, Silhavy T. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019;10(3). PMCID: PMC6529638
    Reference Link
  • 1.
    Xu Y-F, Lu W, Chen J, Johnson S, Gibney P, Thomas D, Brown G, May A, Campagna S, Yakunin A, Botstein D, Rabinowitz J. Discovery and Functional Characterization of a Yeast Sugar Alcohol Phosphatase. ACS Chem Biol. 2018;13(10):3011–3020. PMCID: PMC6466636
    Reference Link
  • 1.
    Trivedi R, Crooks J, Auer G, Pendry J, Foik I, Siryaporn A, Abbott N, Gitai Z, Weibel D. Mechanical Genomic Studies Reveal the Role of d-Alanine Metabolism in Pseudomonas aeruginosa Cell Stiffness. mBio. 2018;9(5). PMCID: PMC6134093
    Reference Link
  • 1.
    Hammer S, Avalos J. Uncovering the role of branched-chain amino acid transaminases in Saccharomyces cerevisiae isobutanol biosynthesis. Metab Eng. 2017;44:302–312. PMID: 29037781
    Reference Link
  • 1.
    Hecht M, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018;48:124–132. PMID: 29306103
    Reference Link
  • 1.
    Ducker G, Ghergurovich J, Mainolfi N, Suri V, Jeong S, Li S, Friedman A, Manfredi M, Gitai Z, Kim H, Rabinowitz J. Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma. Proc Natl Acad Sci U S A. 2017;114(43):11404–11409. PMCID: PMC5664509
    Reference Link
  • 1.
    Duncan J, Stoller M, Francl A, Tissir F, Devenport D, Deans M. Celsr1 coordinates the planar polarity of vestibular hair cells during inner ear development. Dev Biol. 2017;423(2):126–137. PMCID: PMC5369242
    Reference Link
  • 1.
    Bonchuk A, Maksimenko O, Kyrchanova O, Ivlieva T, Mogila V, Deshpande G, Wolle D, Schedl P, Georgiev P. Functional role of dimerization and CP190 interacting domains of CTCF protein in Drosophila melanogaster. BMC Biol. 2015;13:63. PMCID: PMC4528719
    Reference Link
  • 1.
    Titchenell P, Quinn W, Lu M, Chu Q, Lu W, Li C, Chen H, Monks B, Chen J, Rabinowitz J, Birnbaum M. Direct Hepatocyte Insulin Signaling Is Required for Lipogenesis but Is Dispensable for the Suppression of Glucose Production. Cell Metab. 2016;23(6):1154–1166. PMCID: PMC4909537
    Reference Link
  • 1.
    Guo J, Teng X, Laddha S, Ma S, Van Nostrand S, Yang Y, Khor S, Chan C, Rabinowitz J, White E. Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells. Genes Dev. 2016;30(15):1704–17. PMCID: PMC5002976
    Reference Link
  • 1.
    Ding Q, Heller B, Capuccino J, Song B, Nimgaonkar I, Hrebikova G, Contreras J, Ploss A. Hepatitis E virus ORF3 is a functional ion channel required for release of infectious particles. Proc Natl Acad Sci U S A. 2017;114(5):1147–1152. PMCID: PMC5293053
    Reference Link
  • 1.
    Jonikas M, Collins S, Denic V, Oh E, Quan E, Schmid V, Weibezahn J, Schwappach B, Walter P, Weissman J, Schuldiner M. Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum. Science. 2009;323(5922):1693–7. PMCID: PMC2877488
    Reference Link
  • 1.
    Smith B, Mularz A, Hecht M. Divergent evolution of a bifunctional de novo protein. Protein Sci. 2015;24(2):246–52. PMCID: PMC4315662
    Reference Link
  • 1.
    Stundon J, Zakian V. Identification of Saccharomyces cerevisiae Genes Whose Deletion Causes Synthetic Effects in Cells with Reduced Levels of the Nuclear Pif1 DNA Helicase. G3 (Bethesda). 2015;5(12):2913–8. PMCID: PMC4683662
    Reference Link
  • 1.
    Hammer B, Bassler B. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol. 2003;50(1):101–4. PMID: 14507367
    Reference Link
  • 1.
    Lenz D, Mok K, Lilley B, Kulkarni R, Wingreen N, Bassler B. The small RNA chaperone Hfq and multiple small RNAs control quorum sensing in Vibrio harveyi and Vibrio cholerae. Cell. 2004;118(1):69–82. PMID: 15242645
    Reference Link
  • 1.
    Rader B, Campagna S, Semmelhack M, Bassler B, Guillemin K. The quorum-sensing molecule autoinducer 2 regulates motility and flagellar morphogenesis in Helicobacter pylori. J Bacteriol. 2007;189(17):6109–17. PMCID: PMC1951907
    Reference Link
  • 1.
    Svenningsen S, Tu K, Bassler B. Gene dosage compensation calibrates four regulatory RNAs to control Vibrio cholerae quorum sensing. EMBO J. 2009;28(4):429–39. PMCID: PMC2632942
    Reference Link
  • 1.
    Waters C, Wu J, Ramsey M, Harris R, Bassler B. Control of the type 3 secretion system in Vibrio harveyi by quorum sensing through repression of ExsA. Appl Environ Microbiol. 2010;76(15):4996–5004. PMCID: PMC2916497
    Reference Link

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