Department of Molecular Biology

Off screen link: Skip to content Off screen link: Skip to search
Princeton University
Home

Main Menu

  • Department
    Department
    • Chair’s Welcome
    • Administration & Staff
    • Associated Programs, Institutes & Departments
    • Grants Submission Policy & Funding Opportunities
    • Open Positions
    • MolBio Annual Retreat
      • MolBio Retreat Archive
        • 2024 MolBio Retreat Schedule
        • MolBio Retreat 2023 Schedule
  • Faculty & Research
    Faculty & Research
    • Faculty
    • Research Areas
      • Biochemistry, Biophysics & Structural Biology
      • Cell Biology, Development & Cancer
      • Genetics & Genomics
      • Microbiology, Virology & Immunology
      • Quantitative & Computational Biology
  • Postdoc
    Postdoc
    • Overview
    • Prospective Postdoc
    • New Postdoc
    • Postdoc Community
    • Career Development
    • Lewis-Sigler Fellows
    • Contacts
  • Graduate
    Graduate
    • Overview
    • Admission & Financial Support
    • Requirements
    • Courses
    • MD/PhD Program
    • MolBio Scholars
    • Outreach Program
    • Faculty Graduate Committee
    • Department Life
      • Life in the Department
      • Graduate Student Committees
      • Career Resources
      • Student Life
      • Incoming Graduate Students
    • Molecular Biology Training Grants
  • Undergraduate
    Undergraduate
    • Overview
    • Teaching Mission
    • Major
      • Major Requirements
      • Departmentals
      • Declare a Major
      • Typical Paths
      • Courses
      • Minor & Certificate Programs
      • Study Abroad
      • Junior Independent Work
      • Senior Thesis
    • Research
      • Current Lab Assignments
      • Summer Research
      • Sophomore Research Course
      • Internship Milestone Credit
      • Undergraduate Publications
    • Career Resources
    • Community
      • Undergraduate Community
      • Important Dates and Deadlines
      • Class Day
    • Contacts
  • Core Facilities
    Core Facilities
    • Overview
    • Shared Imaging Facilities
      • Confocal Microscopy
        • Instruments
        • Fluorescent Dyes
        • ILab Calendar and Service Requests
        • User Training
        • Nikon Center of Excellence
        • Contact
      • Electron Microscopy
        • Equipment
        • Pricing
        • Contacts
      • Imaging & Analysis Center
      • Nikon Center of Excellence
    • Shared Research Facilities
      • Biophysics
      • Drosophila Media
      • Flow Cytometry
        • Facility Use
        • Instruments
        • ILab Calendar and Service Requests
        • Contact
      • Genome Editing Shared Resource (Rutgers-CINJ)
      • Histology
      • Lab Animal Resources
      • Macromolecular Crystallography
      • NMR Facility
      • Proteomics & Mass Spec
        • Proteomics & MS Services
        • Protocols & Guidelines
      • Research Computing
      • Sequencing & Microarray
      • Synseq
    • Other Facilities
      • IT Support
      • Facilities & Maintenance
      • Environmental Health & Safety (EHS)
  • Community
    Community
    • Community & Connection Committee
    • Code of Conduct
  • Apply & Visit
  • Contact
  • People
  • Donors
  • News
  • Events
    • Events Archive

Search

Fatty Acids

  • 1.
    Zhang Z, TeSlaa T, Xu X, Zeng X, Yang L, Xing G, Tesz G, Clasquin M, Rabinowitz J. Serine catabolism generates liver NADPH and supports hepatic lipogenesis. Nat Metab. 2021;3(12):1608–1620. PMCID: PMC8721747
    Reference Link
  • 1.
    Ringel A, Drijvers J, Baker G, Catozzi A, García-Cañaveras J, Gassaway B, Miller B, Juneja V, Nguyen T, Joshi S, Yao C-H, Yoon H, Sage P, LaFleur M, Trombley J, Jacobson C, Maliga Z, Gygi S, Sorger P, Rabinowitz J, Sharpe A, Haigis M. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020;183(7):1848–1866.e26. PMCID: PMC8064125
    Reference Link
  • 1.
    Murashige D, Jang C, Neinast M, Edwards J, Cowan A, Hyman M, Rabinowitz J, Frankel D, Arany Z. Comprehensive quantification of fuel use by the failing and nonfailing human heart. Science. 2020;370(6514):364–368. PMCID: PMC7871704
    Reference Link
  • 1.
    Hui S, Cowan A, Zeng X, Yang L, TeSlaa T, Li X, Bartman C, Zhang Z, Jang C, Wang L, Lu W, Rojas J, Baur J, Rabinowitz J. Quantitative Fluxomics of Circulating Metabolites. Cell Metab. 2020;32(4):676–688.e4. PMCID: PMC7544659
    Reference Link
  • 1.
    Zhao S, Jang C, Liu J, Uehara K, Gilbert M, Izzo L, Zeng X, Trefely S, Fernandez S, Carrer A, Miller K, Schug Z, Snyder N, Gade T, Titchenell P, Rabinowitz J, Wellen K. Dietary fructose feeds hepatic lipogenesis via microbiota-derived acetate. Nature. 2020;579(7800):586–591. PMCID: PMC7416516
    Reference Link
  • 1.
    Hashimoto Y, Sheng X, Murray-Nerger L, Cristea I. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020;11(1):806. PMCID: PMC7010728
    Reference Link
  • 1.
    Jang C, Hui S, Zeng X, Cowan A, Wang L, Chen L, Morscher R, Reyes J, Frezza C, Hwang H, Imai A, Saito Y, Okamoto K, Vaspoli C, Kasprenski L, Zsido G, Gorman J, Gorman R, Rabinowitz J. Metabolite Exchange between Mammalian Organs Quantified in Pigs. Cell Metab. 2019;30(3):594–606.e3. PMCID: PMC6726553
    Reference Link
  • 1.
    Yan R, Zhang J, Park H-J, Park E, Oh S, Zheng H, Junn E, Voronkov M, Stock J, Mouradian M. Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson’s disease and DLB. Proc Natl Acad Sci U S A. 2018;115(51):E12053-E12062. PMCID: PMC6304960
    Reference Link
  • 1.
    Wu Y, Seyedsayamdost M. The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry. 2018;57(29):4247–4251. PMID: 29975047
    Reference Link
  • 1.
    Zhang Z, Chen L, Liu L, Su X, Rabinowitz J. Chemical Basis for Deuterium Labeling of Fat and NADPH. J Am Chem Soc. 2017;139(41):14368–14371. PMCID: PMC5748894
    Reference Link
  • 1.
    Liu L, Rowe G, Yang S, Li J, Damilano F, Chan M, Lu W, Jang C, Wada S, Morley M, Hesse M, Fleischmann B, Rabinowitz J, Das S, Rosenzweig A, Arany Z. PDK4 Inhibits Cardiac Pyruvate Oxidation in Late Pregnancy. Circ Res. 2017;121(12):1370–1378. PMCID: PMC5722682
    Reference Link
  • 1.
    Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey J, Yu Y, Liu X, He L, Cavaliere P, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure N, Blackwell K, Yu J, Rabinowitz J, Cantley L, Blenis J. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017;171(7):1545–1558.e18. PMCID: PMC5920692
    Reference Link
  • 1.
    Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, Filisio F, Giles-Davis W, Xu X, Karakousis G, Schuchter L, Xu W, Amaravadi R, Xiao M, Sadek N, Krepler C, Herlyn M, Freeman G, Rabinowitz J, Ertl H. Enhancing CD8 T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32(3):377–391.e9. PMCID: PMC5751418
    Reference Link
  • 1.
    Li Z, Kang Y. Lipid Metabolism Fuels Cancer’s Spread. Cell Metab. 2017;25(2):228–230. PMID: 28178563
    Reference Link
  • 1.
    Papazyan R, Sun Z, Kim Y, Titchenell P, Hill D, Lu W, Damle M, Wan M, Zhang Y, Briggs E, Rabinowitz J, Lazar M. Physiological Suppression of Lipotoxic Liver Damage by Complementary Actions of HDAC3 and SCAP/SREBP. Cell Metab. 2016;24(6):863–874. PMCID: PMC5159233
    Reference Link
  • 1.
    Li X, Zhang R, Patena W, Gang S, Blum S, Ivanova N, Yue R, Robertson J, Lefebvre P, Fitz-Gibbon S, Grossman A, Jonikas M. An Indexed, Mapped Mutant Library Enables Reverse Genetics Studies of Biological Processes in Chlamydomonas reinhardtii. Plant Cell. 2016;28(2):367–87. PMCID: PMC4790863
    Reference Link
  • 1.
    Jang C, Oh S, Wada S, Rowe G, Liu L, Chan M, Rhee J, Hoshino A, Kim B, Ibrahim A, Baca L, Kim E, Ghosh C, Parikh S, Jiang A, Chu Q, Forman D, Lecker S, Krishnaiah S, Rabinowitz J, Weljie A, Baur J, Kasper D, Arany Z. A branched-chain amino acid metabolite drives vascular fatty acid transport and causes insulin resistance. Nat Med. 2016;22(4):421–6. PMCID: PMC4949205
    Reference Link
  • 1.
    Purdy J, Shenk T, Rabinowitz J. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Rep. 2015;10(8):1375–85. PMCID: PMC4354725
    Reference Link
  • 1.
    Sutterlin H, Shi H, May K, Miguel A, Khare S, Huang K, Silhavy T. Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A. 2016;113(11):E1565–74. PMCID: PMC4801249
    Reference Link
  • 1.
    Perez L, Ng W-L, Marano P, Brook K, Bassler B, Semmelhack M. Role of the CAI-1 fatty acid tail in the Vibrio cholerae quorum sensing response. J Med Chem. 2012;55(22):9669–81. PMCID: PMC3798069
    Reference Link

Footer

Connect with Mol Bio

  • Facebook
  • Twitter

Department of Molecular Biology
119 Lewis Thomas Laboratory
Washington Road
Princeton, NJ 08544-1014
Need help? Contact us

Visitor Parking Information

Intranet Login

Privacy Notice

Explore

  • Graduate Program
  • Undergraduate Program
  • Summer Undergraduate Research Program (SURP)
  • Research Areas
  • Molecular Biology Faculty
  • Faculty Research Labs

Core Facilities & Instruments

  • Biophysics
  • Confocal Microscopy
  • Drosophila Media
  • Electron Microscopy
  • Flow Cytometry
  • Histology
  • Imaging Facility at LSI
  • Laboratory Animal Resources
  • Macromolecular Crystallography
  • Nikon Center of Excellence
  • Proteomics & Mass Spectrometry
  • Sequencing & Microarray
  • Synseq

Programs & Institutes

  • Graduate Program in Quantitative and Computational Biology
  • Glenn Laboratories For Aging Research
  • Lewis-Sigler Institute for Integrative Genomics
  • Princeton Neuroscience Institute
  • Diversity & Non-Discrimination
  • Accessibility Help

© 2025 The Trustees of Princeton University

Princeton University