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Extracellular Matrix

  • 1.
    Tomer D, Arriagada C, Munshi S, Alexander B, French B, Vedula P, Caorsi V, House A, Guvendiren M, Kashina A, Schwarzbauer J, Astrof S. A new mechanism of fibronectin fibril assembly revealed by live imaging and super-resolution microscopy. J Cell Sci. 2022;135(16). PMCID: PMC9481930
    Reference Link
  • 1.
    Resnikoff H, Miller C, Schwarzbauer J. Implications of fibrotic extracellular matrix in diabetic retinopathy. Exp Biol Med (Maywood). 2022;247(13):1093–1102. PMCID: PMC9335512
    Reference Link
  • 1.
    Farahani P, Lemke S, Dine E, Uribe G, Toettcher J, Nelson C. Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021;37(13):110181. PMCID: PMC8756379
    Reference Link
  • 1.
    Sharma A, Schwarzbauer J. Differential Regulation of Neurite Outgrowth and Growth Cone Morphology by 3D Fibronectin and Fibronectin-Collagen Extracellular Matrices. Mol Neurobiol. 2022;59(2):1112–1123. PMCID: PMC8858852
    Reference Link
  • 1.
    Hill K, Lovett B, Schwarzbauer J. Heparan sulfate is necessary for the early formation of nascent fibronectin and collagen I fibrils at matrix assembly sites. J Biol Chem. 2022;298(1):101479. PMCID: PMC8801470
    Reference Link
  • 1.
    Rabie E, Zhang S, Dunn C, Nelson C. Substratum stiffness signals through integrin-linked kinase and β1-integrin to regulate midbody proteins and abscission during EMT. Mol Biol Cell. 2021;32(18):1664–1676. PMCID: PMC8684726
    Reference Link
  • 1.
    Narla A, Borenstein D, Wingreen N. A biophysical limit for quorum sensing in biofilms. Proc Natl Acad Sci U S A. 2021;118(21). PMCID: PMC8166027
    Reference Link
  • 1.
    Nerger B, Jaslove J, Elashal H, Mao S, Košmrlj A, Link J, Nelson C. Local accumulation of extracellular matrix regulates global morphogenetic patterning in the developing mammary gland. Curr Biol. 2021;31(9):1903–1917.e6. PMCID: PMC8119325
    Reference Link
  • 1.
    Garrison C, Schwarzbauer J. Fibronectin fibril alignment is established upon initiation of extracellular matrix assembly. Mol Biol Cell. 2021;32(8):739–752. PMCID: PMC8108514
    Reference Link
  • 1.
    Rabie E, Zhang S, Kourouklis A, Kilinc N, Simi A, Radisky D, Tien J, Nelson C. Matrix degradation and cell proliferation are coupled to promote invasion and escape from an engineered human breast microtumor. Integr Biol (Camb). 2021;13(1):17–29. PMCID: PMC7856634
    Reference Link
  • 1.
    Alizzi R, Xu D, Tenenbaum C, Wang W, Gavis E. The ELAV/Hu protein Found in neurons regulates cytoskeletal and ECM adhesion inputs for space-filling dendrite growth. PLoS Genet. 2020;16(12):e1009235. PMCID: PMC7793258
    Reference Link
  • 1.
    Fiore V, Krajnc M, Quiroz F, Levorse J, Pasolli A, Shvartsman S, Fuchs E. Mechanics of a multilayer epithelium instruct tumour architecture and function. Nature. 2020;585(7825):433–439. PMCID: PMC7787055
    Reference Link
  • 1.
    Anlas A, Nelson C. Living under Strain: How Epithelia Protect Their Genomes from Repeated Stretching. Biochemistry. 2020;59(30):2761–2763. PMID: 32702973
    Reference Link
  • 1.
    Vega M, Kastberger B, Wehrle-Haller B, Schwarzbauer J. Stimulation of Fibronectin Matrix Assembly by Lysine Acetylation. Cells. 2020;9(3). PMCID: PMC7140634
    Reference Link
  • 1.
    Liverani C, De Vita A, Minardi S, Kang Y, Mercatali L, Amadori D, Bongiovanni A, La Manna F, Ibrahim T, Tasciotti E. A biomimetic 3D model of hypoxia-driven cancer progression. Sci Rep. 2019;9(1):12263. PMCID: PMC6706452
    Reference Link
  • 1.
    Spurlin J, Siedlik M, Nerger B, Pang M-F, Jayaraman S, Zhang R, Nelson C. Mesenchymal proteases and tissue fluidity remodel the extracellular matrix during airway epithelial branching in the embryonic avian lung. Development. 2019;146(16). PMCID: PMC6737900
    Reference Link
  • 1.
    Saunders J, Schwarzbauer J. Fibronectin matrix as a scaffold for procollagen proteinase binding and collagen processing. Mol Biol Cell. 2019;30(17):2218–2226. PMCID: PMC6743462
    Reference Link
  • 1.
    Yan J, Moreau A, Khodaparast S, Perazzo A, Feng J, Fei C, Mao S, Mukherjee S, Košmrlj A, Wingreen N, Bassler B, Stone H. Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. Adv Mater. 2018;30(46):e1804153. PMCID: PMC8865467
    Reference Link
  • 1.
    Simi A, Pang M-F, Nelson C. Extracellular Matrix Stiffness Exists in a Feedback Loop that Drives Tumor Progression. Adv Exp Med Biol. 2018;1092:57–67. PMID: 30368748
    Reference Link
  • 1.
    Han S, Pang M-F, Nelson C. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018;131(8). PMCID: PMC5963841
    Reference Link
  • 1.
    Sauls K, Greco T, Wang L, Zou M, Villasmil M, Qian L, Cristea I, Conlon F. Initiating Events in Direct Cardiomyocyte Reprogramming. Cell Rep. 2018;22(7):1913–1922. PMCID: PMC6045814
    Reference Link
  • 1.
    Harris G, Raitman I, Schwarzbauer J. Cell-derived decellularized extracellular matrices. Methods Cell Biol. 2018;143:97–114. PMCID: PMC5995326
    Reference Link
  • 1.
    Raitman I, Huang M, Williams S, Friedman B, Godula K, Schwarzbauer J. Heparin-fibronectin interactions in the development of extracellular matrix insolubility. Matrix Biol. 2018;67:107–122. PMCID: PMC5910196
    Reference Link
  • 1.
    Yan J, Nadell C, Stone H, Wingreen N, Bassler B. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nat Commun. 2017;8(1):327. PMCID: PMC5569112
    Reference Link
  • 1.
    Piotrowski-Daspit A, Nerger B, Wolf A, Sundaresan S, Nelson C. Dynamics of Tissue-Induced Alignment of Fibrous Extracellular Matrix. Biophys J. 2017;113(3):702–713. PMCID: PMC5550306
    Reference Link
  • 1.
    Beroz F, Jawerth L, Münster S, Weitz D, Broedersz C, Wingreen N. Physical limits to biomechanical sensing in disordered fibre networks. Nat Commun. 2017;8:16096. PMCID: PMC5520107
    Reference Link
  • 1.
    Goyal R, Vega M, Pastino A, Singh S, Guvendiren M, Kohn J, Murthy S, Schwarzbauer J. Development of hybrid scaffolds with natural extracellular matrix deposited within synthetic polymeric fibers. J Biomed Mater Res A. 2017;105(8):2162–2170. PMCID: PMC5493328
    Reference Link
  • 1.
    Goodwin K, Nelson C. Generating tissue topology through remodeling of cell-cell adhesions. Exp Cell Res. 2017;358(1):45–51. PMCID: PMC5544595
    Reference Link
  • 1.
    Vega M, Schwarzbauer J. Collaboration of fibronectin matrix with other extracellular signals in morphogenesis and differentiation. Curr Opin Cell Biol. 2016;42:1–6. PMCID: PMC5055409
    Reference Link
  • 1.
    Miller C, Budoff G, Prenner J, Schwarzbauer J. Minireview: Fibronectin in retinal disease. Exp Biol Med (Maywood). 2017;242(1):1–7. PMCID: PMC5206986
    Reference Link
  • 1.
    Gjorevski N, Piotrowski A, Varner V, Nelson C. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep. 2015;5:11458. PMCID: PMC4499882
    Reference Link
  • 1.
    Piotrowski-Daspit A, Nelson C. Engineering Three-dimensional Epithelial Tissues Embedded within Extracellular Matrix. J Vis Exp. 2016;(113). PMCID: PMC4993436
    Reference Link
  • 1.
    Harris G, Madigan N, Lancaster K, Enquist L, Windebank A, Schwartz J, Schwarzbauer J. Nerve Guidance by a Decellularized Fibroblast Extracellular Matrix. Matrix Biol. 2017;60-61:176–189. PMCID: PMC5352540
    Reference Link
  • 1.
    Pastino A, Greco T, Mathias R, Cristea I, Schwarzbauer J. Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly. Matrix Biol. 2017;59:39–53. PMCID: PMC5237628
    Reference Link
  • 1.
    Tanentzapf G, Devenport D, Godt D, Brown N. Integrin-dependent anchoring of a stem-cell niche. Nat Cell Biol. 2007;9(12):1413–8. PMCID: PMC3529653
    Reference Link
  • 1.
    Miller C, Pozzi A, Zent R, Schwarzbauer J. Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells. Mol Biol Cell. 2014;25(16):2342–50. PMCID: PMC4142608
    Reference Link
  • 1.
    Nadell C, Drescher K, Wingreen N, Bassler B. Extracellular matrix structure governs invasion resistance in bacterial biofilms. ISME J. 2015;9(8):1700–9. PMCID: PMC4511925
    Reference Link

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