1.Zhang D, Li S, King C, Wingreen N, Gitai Z, Li Z. Global and gene-specific translational regulation in Escherichia coli across different conditions. PLoS Comput Biol. 2022;18(10):e1010641. PMCID: PMC9624429 Reference Link
1.Doyle M, Jimah J, Dowdy T, Ohlemacher S, Larion M, Hinshaw J, Bernstein H. Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022;185(7):1143–1156.e13. PMCID: PMC8985213 Reference Link
1.Benn G, Mikheyeva I, Inns P, Forster J, Ojkic N, Bortolini C, Ryadnov M, Kleanthous C, Silhavy T, Hoogenboom B. Phase separation in the outer membrane of . Proc Natl Acad Sci U S A. 2021;118(44). PMCID: PMC8612244 Reference Link
1.Combs A, Silhavy T. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022;119(1). PMCID: PMC8740687 Reference Link
1.Wan X, Brynildsen M. Robustness of nitric oxide detoxification to nitrogen starvation in Escherichia coli requires RelA. Free Radic Biol Med. 2021;176:286–297. PMID: 34624482 Reference Link
1.Murawski A, Brynildsen M. Ploidy is an important determinant of fluoroquinolone persister survival. Curr Biol. 2021;31(10):2039–2050.e7. PMCID: PMC8183807 Reference Link
1.Seath C, Trowbridge A, Muir T, MacMillan D. Reactive intermediates for interactome mapping. Chem Soc Rev. 2021;50(5):2911–2926. PMID: 33458734 Reference Link
1.Guest R, Rutherford S, Silhavy T. Border Control: Regulating LPS Biogenesis. Trends Microbiol. 2021;29(4):334–345. PMCID: PMC7969359 Reference Link
1.Grimm J, Shi H, Wang W, Mitchell A, Wingreen N, Huang K, Silhavy T. The inner membrane protein YhdP modulates the rate of anterograde phospholipid flow in . Proc Natl Acad Sci U S A. 2020;117(43):26907–26914. PMCID: PMC7604412 Reference Link
1.Hart E, Silhavy T. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020;202(21). PMCID: PMC7549358 Reference Link
1.Yao X, Fan X, Yan N. Cryo-EM analysis of a membrane protein embedded in the liposome. Proc Natl Acad Sci U S A. 2020;117(31):18497–18503. PMCID: PMC7414195 Reference Link
1.Hart E, Gupta M, Wühr M, Silhavy T. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proc Natl Acad Sci U S A. 2020;117(31):18737–18743. PMCID: PMC7414184 Reference Link
1.Werner J, Shi H, Hsin J, Huang K, Gitai Z, Klein E. AimB Is a Small Protein Regulator of Cell Size and MreB Assembly. Biophys J. 2020;119(3):593–604. PMCID: PMC7399478 Reference Link
1.Guest R, Guerra D, Wissler M, Grimm J, Silhavy T. YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide. mBio. 2020;11(2). PMCID: PMC7157816 Reference Link
1.Hart E, Mitchell A, Konovalova A, Grabowicz M, Sheng J, Han X, Rodriguez-Rivera F, Schwaid A, Malinverni J, Balibar C, Bodea S, Si Q, Wang H, Homsher M, Painter R, Ogawa A, Sutterlin H, Roemer T, Black T, Rothman D, Walker S, Silhavy T. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019;116(43):21748–21757. PMCID: PMC6815139 Reference Link
1.Schober A, Mathis A, Ingle C, Park J, Chen L, Rabinowitz J, Junier I, Rivoire O, Reynolds K. A Two-Enzyme Adaptive Unit within Bacterial Folate Metabolism. Cell Rep. 2019;27(11):3359–3370.e7. PMCID: PMC6625508 Reference Link
1.Adolfsen K, Chou W, Brynildsen M. Transcriptional Regulation Contributes to Prioritized Detoxification of Hydrogen Peroxide over Nitric Oxide. J Bacteriol. 2019;201(14). PMCID: PMC6597392 Reference Link
1.Aedo S, Orman M, Brynildsen M. Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition. BMC Microbiol. 2019;19(1):140. PMCID: PMC6591824 Reference Link
1.Hart E, Gupta M, Wühr M, Silhavy T. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019;10(3). PMCID: PMC6529638 Reference Link
1.Silhavy T, Mitchell A. Genetic Analysis of Protein Translocation. Protein J. 2019;38(3):217–228. PMCID: PMC6589372 Reference Link
1.Stubbe J, Seyedsayamdost M. Discovery of a New Class I Ribonucleotide Reductase with an Essential DOPA Radical and NO Metal as an Initiator of Long-Range Radical Transfer. Biochemistry. 2019;58(6):435–437. PMID: 30586288 Reference Link
1.Ricci D, Silhavy T. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019;8(2). PMCID: PMC6419762 Reference Link
1.Barrett T, Mok W, Murawski A, Brynildsen M. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019;10(1):1177. PMCID: PMC6414640 Reference Link
1.Hart E, O’Connell A, Tang K, Wzorek J, Grabowicz M, Kahne D, Silhavy T. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019;201(11). PMCID: PMC6509652 Reference Link
1.Chou W, Brynildsen M. Loss of DksA leads to multi-faceted impairment of nitric oxide detoxification by Escherichia coli. Free Radic Biol Med. 2019;130:288–296. PMID: 30366060 Reference Link
1.Mitchell A, Srikumar T, Silhavy T. Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. mBio. 2018;9(4). PMCID: PMC6083912 Reference Link
1.Bratton B, Shaevitz J, Gitai Z, Morgenstein R. MreB polymers and curvature localization are enhanced by RodZ and predict E. coli’s cylindrical uniformity. Nat Commun. 2018;9(1):2797. PMCID: PMC6052060 Reference Link
1.Li S, Li Z, Park J, King C, Rabinowitz J, Wingreen N, Gitai Z. Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. Nat Microbiol. 2018;3(8):939–947. PMCID: PMC6278830 Reference Link
1.Mok W, Brynildsen M. Timing of DNA damage responses impacts persistence to fluoroquinolones. Proc Natl Acad Sci U S A. 2018;115(27):E6301-E6309. PMCID: PMC6142227 Reference Link
1.Konovalova A, Grabowicz M, Balibar C, Malinverni J, Painter R, Riley D, Mann P, Wang H, Garlisi C, Sherborne B, Rigel N, Ricci D, Black T, Roemer T, Silhavy T, Walker S. Inhibitor of intramembrane protease RseP blocks the σ response causing lethal accumulation of unfolded outer membrane proteins. Proc Natl Acad Sci U S A. 2018;115(28):E6614-E6621. PMCID: PMC6048503 Reference Link
1.Shi H, Bratton B, Gitai Z, Huang K. How to Build a Bacterial Cell: MreB as the Foreman of E. coli Construction. Cell. 2018;172(6):1294–1305. PMCID: PMC5846203 Reference Link
1.May K, Silhavy T. The Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling. mBio. 2018;9(2). PMCID: PMC5874903 Reference Link
1.Reece S, Seyedsayamdost M. Long-range proton-coupled electron transfer in the class Ia ribonucleotide reductase. Essays Biochem. 2017;61(2):281–292. PMID: 28487404 Reference Link
1.Szwajkajzer D, Dai L, Fukayama J, Abramczyk B, Fairman R, Carey J. Quantitative analysis of DNA binding by the Escherichia coli arginine repressor. J Mol Biol. 2001;312(5):949–62. PMID: 11580241 Reference Link
1.Degtjarik O, Brynda J, Ettrichova O, Kuty M, Sinha D, Smatanova I, Carey J, Ettrich R, Řeha D. Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA. J Phys Chem B. 2016;120(22):4867–77. PMID: 27183467 Reference Link
1.Lee J, Sutterlin H, Wzorek J, Mandler M, Hagan C, Grabowicz M, Tomasek D, May M, Hart E, Silhavy T, Kahne D. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018;115(10):2359–2364. PMCID: PMC5877925 Reference Link
1.Hoegler K, Hecht M. Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity. J Mol Evol. 2018;86(2):103–110. PMCID: PMC6116729 Reference Link
1.Hecht M, Zarzhitsky S, Karas C, Chari S. Are natural proteins special? Can we do that?. Curr Opin Struct Biol. 2018;48:124–132. PMID: 29306103 Reference Link
1.Donnelly A, Murphy G, Digianantonio K, Hecht M. A de novo enzyme catalyzes a life-sustaining reaction in Escherichia coli. Nat Chem Biol. 2018;14(3):253–255. PMID: 29334382 Reference Link
1.Wang Y, Huang Y, Wang J, Cheng C, Huang W, Lu P, Xu Y-N, Wang P, Yan N, Shi Y. Structure of the formate transporter FocA reveals a pentameric aquaporin-like channel. Nature. 2009;462(7272):467–72. PMID: 19940917 Reference Link
1.Dang S, Sun L, Huang Y, Lu F, Liu Y, Gong H, Wang J, Yan N. Structure of a fucose transporter in an outward-open conformation. Nature. 2010;467(7316):734–8. PMID: 20877283 Reference Link
1.Lu F, Li S, Jiang Y, Jiang J, Fan H, Lu G, Deng D, Dang S, Zhang X, Wang J, Yan N. Structure and mechanism of the uracil transporter UraA. Nature. 2011;472(7342):243–6. PMID: 21423164 Reference Link
1.Sugihara J, Sun L, Yan N, Kaback R. Dynamics of the L-fucose/H+ symporter revealed by fluorescence spectroscopy. Proc Natl Acad Sci U S A. 2012;109(37):14847–51. PMCID: PMC3443143 Reference Link
1.Sun L, Zeng X, Yan C, Sun X, Gong X, Rao Y, Yan N. Crystal structure of a bacterial homologue of glucose transporters GLUT1-4. Nature. 2012;490(7420):361–6. PMID: 23075985 Reference Link
1.Madej G, Dang S, Yan N, Kaback R. Evolutionary mix-and-match with MFS transporters. Proc Natl Acad Sci U S A. 2013;110(15):5870–4. PMCID: PMC3625355 Reference Link
1.Madej G, Sun L, Yan N, Kaback R. Functional architecture of MFS D-glucose transporters. Proc Natl Acad Sci U S A. 2014;111(7):E719–27. PMCID: PMC3932877 Reference Link
1.Deng D, Xu C, Sun P, Wu J, Yan C, Hu M, Yan N. Crystal structure of the human glucose transporter GLUT1. Nature. 2014;510(7503):121–5. PMID: 24847886 Reference Link
1.Yu X, Yang G, Yan C, Baylon J, Jiang J, Fan H, Lu G, Hasegawa K, Okumura H, Wang T, Tajkhorshid E, Li S, Yan N. Dimeric structure of the uracil:proton symporter UraA provides mechanistic insights into the SLC4/23/26 transporters. Cell Res. 2017;27(8):1020–1033. PMCID: PMC5539350 Reference Link
1.Jiang X, Smirnova I, Kasho V, Wu J, Hirata K, Ke M, Pardon E, Steyaert J, Yan N, Kaback R. Crystal structure of a LacY-nanobody complex in a periplasmic-open conformation. Proc Natl Acad Sci U S A. 2016;113(44):12420–12425. PMCID: PMC5098631 Reference Link
1.Ke M, Yuan Y, Jiang X, Yan N, Gong H. Molecular determinants for the thermodynamic and functional divergence of uniporter GLUT1 and proton symporter XylE. PLoS Comput Biol. 2017;13(6):e1005603. PMCID: PMC5491310 Reference Link