Endonucleases

1.
Chen H, Zhan M, Liu J, Liu Z, Shen M, Yang F, Kang Y, Yin F, Li Z. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022;65(18):12188–12199. PMID: 36044768

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Shen M, Wei Y, Kim H, Wan L, Jiang Y-Z, Hang X, Raba M, Remiszewski S, Rowicki M, Wu C-G, Wu S, Zhang L, Lu X, Yuan M, Smith H, Zheng A, Bertino J, Jin J, Xing Y, Shao Z-M, Kang Y. Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer. 2022;3(1):43–59. PMCID: PMC8818087

Reference Link
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Shen M, Smith H, Wei Y, Jiang Y-Z, Zhao S, Wang N, Rowicki M, Tang Y, Hang X, Wu S, Wan L, Shao Z-M, Kang Y. Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022;3(1):60–74. PMCID: PMC8818088

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1.
Myhrvold C, Freije C, Gootenberg J, Abudayyeh O, Metsky H, Durbin A, Kellner M, Tan A, Paul L, Parham L, Garcia K, Barnes K, Chak B, Mondini A, Nogueira M, Isern S, Michael S, Lorenzana I, Yozwiak N, MacInnis B, Bosch I, Gehrke L, Zhang F, Sabeti P. Field-deployable viral diagnostics using CRISPR-Cas13. Science. 2018;360(6387):444–448. PMCID: PMC6197056

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Hartenian E, Gilbertson S, Federspiel J, Cristea I, Glaunsinger B. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020;16(2):e1008269. PMCID: PMC7032723

Reference Link
1.
Horlbeck M, Gilbert L, Villalta J, Adamson B, Pak R, Chen Y, Fields A, Park C, Corn J, Kampmann M, Weissman J. Compact and highly active next-generation libraries for CRISPR-mediated gene repression and activation. Elife. 2016;5. PMCID: PMC5094855

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