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Drug Resistance, Bacterial

  • 1.
    Tang J, Brynildsen M. Genome-wide mapping of fluoroquinolone-stabilized DNA gyrase cleavage sites displays drug specific effects that correlate with bacterial persistence. Nucleic Acids Res. 2023;51(3):1208–1228. PMCID: PMC9943676
    Reference Link
  • 1.
    Balaich J, Estrella M, Wu G, Jeffrey P, Biswas A, Zhao L, Korennykh A, Donia M. The human microbiome encodes resistance to the antidiabetic drug acarbose. Nature. 2021;600(7887):110–115. PMCID: 3552296
    Reference Link
  • 1.
    Martin J, Sheehan J, Bratton B, Moore G, Mateus A, Li S, Kim H, Rabinowitz J, Typas A, Savitski M, Wilson M, Gitai Z. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020;181(7):1518–1532.e14. PMCID: PMC7780349
    Reference Link
  • 1.
    Hart E, Mitchell A, Konovalova A, Grabowicz M, Sheng J, Han X, Rodriguez-Rivera F, Schwaid A, Malinverni J, Balibar C, Bodea S, Si Q, Wang H, Homsher M, Painter R, Ogawa A, Sutterlin H, Roemer T, Black T, Rothman D, Walker S, Silhavy T. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019;116(43):21748–21757. PMCID: PMC6815139
    Reference Link
  • 1.
    Yan J, Bassler B. Surviving as a Community: Antibiotic Tolerance and Persistence in Bacterial Biofilms. Cell Host Microbe. 2019;26(1):15–21. PMCID: PMC6629468
    Reference Link
  • 1.
    Aedo S, Orman M, Brynildsen M. Stationary phase persister formation in Escherichia coli can be suppressed by piperacillin and PBP3 inhibition. BMC Microbiol. 2019;19(1):140. PMCID: PMC6591824
    Reference Link
  • 1.
    Liu M, El-Hossary E, Oelschlaeger T, Donia M, Quinn R, Abdelmohsen U. Potential of marine natural products against drug-resistant bacterial infections. Lancet Infect Dis. 2019;19(7):e237-e245. PMID: 31031171
    Reference Link
  • 1.
    Barrett T, Mok W, Murawski A, Brynildsen M. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019;10(1):1177. PMCID: PMC6414640
    Reference Link
  • 1.
    Orman M, Brynildsen M. Inhibition of stationary phase respiration impairs persister formation in E. coli. Nat Commun. 2015;6:7983. PMCID: PMC4530465
    Reference Link
  • 1.
    Orman M, Brynildsen M. Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide. Free Radic Biol Med. 2016;93:145–54. PMCID: PMC4898466
    Reference Link

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