1.Howard T, Lum K, Kennedy M, Cristea I. The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection. mSystems. 2022;7(3):e0019822. PMCID: PMC9239196 Reference Link
1.Wei L, Ploss A. Mechanism of Hepatitis B Virus cccDNA Formation. Viruses. 2021;13(8). PMCID: PMC8402782 Reference Link
1.Song B, Liu D, Greco T, Cristea I. Post-translational modification control of viral DNA sensors and innate immune signaling. Adv Virus Res. 2021;109:163–199. PMCID: PMC8489191 Reference Link
1.Wei L, Ploss A. Hepatitis B virus cccDNA is formed through distinct repair processes of each strand. Nat Commun. 2021;12(1):1591. PMCID: PMC7952586 Reference Link
1.Lum K, Cristea I. Host Innate Immune Response and Viral Immune Evasion During Alphaherpesvirus Infection. Curr Issues Mol Biol. 2021;42:635–686. PMCID: PMC8301600 Reference Link
1.Howard T, Cristea I. Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective. Biomolecules. 2020;10(12). PMCID: PMC7761228 Reference Link
1.Wei L, Ploss A. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020;5(5):715–726. PMCID: PMC7190442 Reference Link
1.Lum K, Howard T, Pan C, Cristea I. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA. mBio. 2019;10(4). PMCID: PMC6650555 Reference Link
1.Chen S, Shenk T, Nogalski M. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019;116(38):18971–18982. PMCID: PMC6754545 Reference Link
1.Hung G, Flint S. Normal human cell proteins that interact with the adenovirus type 5 E1B 55kDa protein. Virology. 2017;504:12–24. PMCID: PMC5337154 Reference Link
1.Diner B, Cristea I. Blowing Off Steam: Virus Inhibition of cGAS DNA Sensing. Cell Host Microbe. 2015;18(3):270–2. PMCID: PMC4920077 Reference Link
1.Diner B, Lum K, Javitt A, Cristea I. Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. Mol Cell Proteomics. 2015;14(9):2341–56. PMCID: PMC4563720 Reference Link
1.Diner B, Lum K, Toettcher J, Cristea I. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection. mBio. 2016;7(6). PMCID: PMC5111403 Reference Link
1.Diner B, Li T, Greco T, Crow M, Fuesler J, Wang J, Cristea I. The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. Mol Syst Biol. 2015;11(1):787. PMCID: PMC4358659 Reference Link
1.Chahal J, Gallagher C, DeHart C, Flint S. The repression domain of the E1B 55-kilodalton protein participates in countering interferon-induced inhibition of adenovirus replication. J Virol. 2013;87(8):4432–44. PMCID: PMC3624377 Reference Link
