Kennedy M, Greco T, Song B, Cristea I. HTT-OMNI: A Web-based Platform for Huntingtin Interaction Exploration and Multi-omics Data Integration. Mol Cell Proteomics. 2022;21(10):100275. PMCID: PMC9540350

Kenney D, O’Connell A, Turcinovic J, Montanaro P, Hekman R, Tamura T, Berneshawi A, Cafiero T, Abdullatif S, Blum B, Goldstein S, Heller B, Gertje H, Bullitt E, Trachtenberg A, Chavez E, Nono E, Morrison C, Tseng A, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber B, Saeed M, Balazs A, Francis K, Klose A, Paragas N, Campbell J, Connor J, Emili A, Crossland N, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022;39(3):110714. PMCID: PMC8977517

Klibaite U, Kislin M, Verpeut J, Bergeler S, Sun X, Shaevitz J, Wang S. Deep phenotyping reveals movement phenotypes in mouse neurodevelopmental models. Mol Autism. 2022;13(1):12. PMCID: PMC8917660

McIntyre L, Huertas F, Morse A, Kaletsky R, Murphy C, Kalia V, Miller G, Moskalenko O, Conesa A, Mor D. GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease. Sci Rep. 2022;12(1):3268. PMCID: PMC8885929

Greco T, Secker C, Ramos E, Federspiel J, Liu J-P, Perez A, Al-Ramahi I, Cantle J, Carroll J, Botas J, Zeitlin S, Wanker E, Cristea I. Dynamics of huntingtin protein interactions in the striatum identifies candidate modifiers of Huntington disease. Cell Syst. 2022;13(4):304–320.e5. PMCID: PMC9317655

Sugiura A, Andrejeva G, Voss K, Heintzman D, Xu X, Madden M, Ye X, Beier K, Chowdhury N, Wolf M, Young A, Greenwood D, Sewell A, Shahi S, Freedman S, Cameron A, Foerch P, Bourne T, García-Cañaveras J, Karijolich J, Newcomb D, Mangalam A, Rabinowitz J, Rathmell J. MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function. Immunity. 2022;55(1):65–81.e9. PMCID: PMC8755618

Meyer M, Wang Y, Edwards D, Smith G, Rubenstein A, Ramanathan P, Mire C, Pietzsch C, Chen X, Ge Y, Cheng W, Henry C, Woods A, Ma L, Stewart-Jones G, Bock K, Minai M, Nagata B, Periasamy S, Shi P-Y, Graham B, Moore I, Ramos I, Troyanskaya O, Zaslavsky E, Carfi A, Sealfon S, Bukreyev A. Attenuated activation of pulmonary immune cells in mRNA-1273-vaccinated hamsters after SARS-CoV-2 infection. J Clin Invest. 2021;131(20). PMCID: PMC8516449

Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias J, Siebel C, Blanco M, Klein-Szanto A, Lengner C, Welm A, Kang Y, Chakrabarti R. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021;12(1):432. PMCID: PMC7813834

Phan T, Nguyen V, Buettner R, Morales C, Yang L, Wong P, Tsai W, Salazar M, Gil Z, Diamond D, Rabinowitz J, Rosen S, Melstrom L. Inhibition of pyrimidine synthesis augments Gemcitabine induced growth inhibition in an immunocompetent model of pancreatic cancer. Int J Biol Sci. 2021;17(9):2240–2251. PMCID: PMC8241727

Liu Y, Maya S, Ploss A. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 2021;13(5). PMCID: PMC8146732

Ploss A, Strick-Marchand H, Li W. Animal Models for Hepatitis B: Does the Supply Meet the Demand?. Gastroenterology. 2021;160(5):1437–1442. PMCID: PMC8035324

Mor D, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller G, Murphy C. Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020;117(42):26438–26447. PMCID: PMC7585014

Ghergurovich J, Esposito M, Chen Z, Wang J, Bhatt V, Lan T, White E, Kang Y, Guo J, Rabinowitz J. Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. Cancer Res. 2020;80(18):3820–3829. PMCID: PMC7501231

Laval K, Maturana C, Enquist L. Mouse Footpad Inoculation Model to Study Viral-Induced Neuroinflammatory Responses. J Vis Exp. 2020;(160). PMID: 32597850

Berggren K, Suzuki S, Ploss A. Animal Models Used in Hepatitis C Virus Research. Int J Mol Sci. 2020;21(11). PMCID: PMC7312079

Moore G, Gitai Z. Both clinical and environmental Caulobacter species are virulent in the Galleria mellonella infection model. PLoS One. 2020;15(3):e0230006. PMCID: PMC7067423

Winer B, Edgel K, Zou X, Sellau J, Hadiwidjojo S, Garver L, McDonough C, Kelleher N, Thomas P, Villasante E, Ploss A, Gerbasi V. Identification of Plasmodium falciparum proteoforms from liver stage models. Malar J. 2020;19(1):10. PMCID: PMC6947969

Akkina R, Barber D, Bility M, Bissig K-D, Burwitz B, Eichelberg K, Endsley J, Garcia V, Hafner R, Karakousis P, Korba B, Koshy R, Lambros C, Menne S, Nuermberger E, Ploss A, Podell B, Poluektova L, Sanders-Beer B, Subbian S, Wahl A. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Curr HIV Res. 2020;18(1):19–28. PMCID: PMC7403688

Ploss A, Kapoor A. Animal Models of Hepatitis C Virus Infection. Cold Spring Harb Perspect Med. 2020;10(5). PMCID: PMC7197424

Wong C, Tang L, Davidson C, Vosburgh E, Chen W, Foran D, Notterman D, Levine A, Xu E. Two well-differentiated pancreatic neuroendocrine tumor mouse models. Cell Death Differ. 2020;27(1):269–283. PMCID: PMC7206057

Federspiel J, Greco T, Lum K, Cristea I. Hdac4 Interactions in Huntington’s Disease Viewed Through the Prism of Multiomics. Mol Cell Proteomics. 2019;18(8 suppl 1):S92-S113. PMCID: PMC6692770

Monsivais D, Peng J, Kang Y, Matzuk M. Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Proc Natl Acad Sci U S A. 2019;116(9):3883–3892. PMCID: PMC6397539

Rodriguez A, Ducker G, Billingham L, Martinez C, Mainolfi N, Suri V, Friedman A, Manfredi M, Weinberg S, Rabinowitz J, Chandel N. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metab. 2019;29(4):1003–1011.e4. PMCID: PMC6447453

Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, Deng Y, Hu X, Zhang J, Gao X, Kang Y, Mercurio A, Goel H, Cheng C. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33(3-4):166–179. PMCID: PMC6362815

Yan R, Zhang J, Park H-J, Park E, Oh S, Zheng H, Junn E, Voronkov M, Stock J, Mouradian M. Synergistic neuroprotection by coffee components eicosanoyl-5-hydroxytryptamide and caffeine in models of Parkinson’s disease and DLB. Proc Natl Acad Sci U S A. 2018;115(51):E12053-E12062. PMCID: PMC6304960

Zhuo W, Liu Y, Li S, Guo D, Sun Q, Jin J, Rao X, Li M, Sun M, Jiang M, Xu Y, Teng L, Jin Y, Si J, Liu W, Kang Y, Zhou T. Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Gastroenterology. 2019;156(3):676–691.e11. PMID: 30445010

Gaska J, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods Mol Biol. 2019;1911:481–503. PMCID: PMC6699619

Badura A, Verpeut J, Metzger J, Pereira T, Pisano T, Deverett B, Bakshinskaya D, Wang S. Normal cognitive and social development require posterior cerebellar activity. Elife. 2018;7. PMCID: PMC6195348

Winer B, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low B, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais M-A, Frankel A, Chiriboga L, Cullen J, Nahass R, Lutgehetmann M, Toettcher J, Wiles M, Schwartz R, Ploss A. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med. 2018;10(447). PMCID: PMC6337727

Douam F, Ploss A. Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. Trends Microbiol. 2018;26(11):913–928. PMCID: PMC6340642

Dragovic S, Agunbiade T, Freudzon M, Yang J, Hastings A, Schleicher T, Zhou X, Craft S, Chuang Y-M, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos G, Fikrig E. Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice. Cell Host Microbe. 2018;23(4):523–535.e5. PMCID: PMC5998332

Douam F, Ploss A. The use of humanized mice for studies of viral pathogenesis and immunity. Curr Opin Virol. 2018;29:62–71. PMCID: PMC5940492

Asam K, Staniszewski A, Zhang H, Melideo S, Mazzeo A, Voronkov M, Huber K, Pérez E, Stock M, Stock J, Arancio O, Nicholls R. Eicosanoyl-5-hydroxytryptamide (EHT) prevents Alzheimer’s disease-related cognitive and electrophysiological impairments in mice exposed to elevated concentrations of oligomeric beta-amyloid. PLoS One. 2017;12(12):e0189413. PMCID: PMC5734769

Nimgaonkar I, Ding Q, Schwartz R, Ploss A. Hepatitis E virus: advances and challenges. Nat Rev Gastroenterol Hepatol. 2018;15(2):96–110. PMID: 29162935

Wooldridge A, Bischof R, Liu H, Heinemann G, Hunter D, Giles L, Simmons R, Lien Y-C, Lu W, Rabinowitz J, Kind K, Owens J, Clifton V, Gatford K. Late-gestation maternal dietary methyl donor and cofactor supplementation in sheep partially reverses protection against allergic sensitization by IUGR. Am J Physiol Regul Integr Comp Physiol. 2018;314(1):R22-R33. PMCID: PMC5866368

Douam F, Albrecht Y, Hrebikova G, Sadimin E, Davidson C, Kotenko S, Ploss A. Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection . mBio. 2017;8(4). PMCID: PMC5559630

Rajeshkumar N, Yabuuchi S, Pai S, De Oliveira E, Kamphorst J, Rabinowitz J, Tejero H, Al-Shahrour F, Hidalgo M, Maitra A, Dang C. Treatment of Pancreatic Cancer Patient-Derived Xenograft Panel with Metabolic Inhibitors Reveals Efficacy of Phenformin. Clin Cancer Res. 2017;23(18):5639–5647. PMCID: PMC6540110

Grant M, Patterson V, Grimes D, Burdine R. Modeling Syndromic Congenital Heart Defects in Zebrafish. Curr Top Dev Biol. 2017;124:1–40. PMID: 28335857

Miller C, Budoff G, Prenner J, Schwarzbauer J. Minireview: Fibronectin in retinal disease. Exp Biol Med (Maywood). 2017;242(1):1–7. PMCID: PMC5206986

Davidson S, Jonas O, Keibler M, Hou H, Luengo A, Mayers J, Wyckoff J, Del Rosario A, Whitman M, Chin C, Condon K, Lammers A, Kellersberger K, Stall B, Stephanopoulos G, Bar-Sagi D, Han J, Rabinowitz J, Cima M, Langer R, Heiden M. Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors. Nat Med. 2017;23(2):235–241. PMCID: PMC5407288

Kang Y. Imaging TGFβ Signaling in Mouse Models of Cancer Metastasis. Methods Mol Biol. 2016;1344:219–32. PMID: 26520127

von Schaewen M, Dorner M, Hueging K, Foquet L, Gerges S, Hrebikova G, Heller B, Bitzegeio J, Doerrbecker J, Horwitz J, Gerold G, Suerbaum S, Rice C, Meuleman P, Pietschmann T, Ploss A. Expanding the Host Range of Hepatitis C Virus through Viral Adaptation. mBio. 2016;7(6). PMCID: PMC5101358

Ding Q, von Schaewen M, Hrebikova G, Heller B, Sandmann L, Plaas M, Ploss A. Mice Expressing Minimally Humanized CD81 and Occludin Genes Support Hepatitis C Virus Uptake In Vivo. J Virol. 2017;91(4). PMCID: PMC5286898

Winer B, Huang T, Low B, Avery C, Pais M-A, Hrebikova G, Siu E, Chiriboga L, Wiles M, Ploss A. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 2017;502:63–72. PMCID: PMC5414730

Cope E, Briones B, Brockett A, Martinez S, Vigneron P-A, Opendak M, Wang S, Gould E. Immature Neurons and Radial Glia, But Not Astrocytes or Microglia, Are Altered in Adult Cntnap2 and Shank3 Mice, Models of Autism. eNeuro. 2016;3(5). PMCID: PMC5066262

von Schaewen M, Hrebikova G, Ploss A. Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens. Methods Mol Biol. 2016;1438:79–101. PMID: 27150085

Ploss A, Walker C. Editorial overview: Progress and challenges in modeling human viral diseases in vivo. Curr Opin Virol. 2015;13:v-vii. PMCID: PMC6040652

Carpenter J, Clayton A, Halling K, Bonthius D, Buckingham E, Jackson W, Dotzler S, Card P, Enquist L, Grose C. Defensive Perimeter in the Central Nervous System: Predominance of Astrocytes and Astrogliosis during Recovery from Varicella-Zoster Virus Encephalitis. J Virol. 2016;90(1):379–91. PMCID: PMC4702565

Siu E, Ploss A. Modeling malaria in humanized mice: opportunities and challenges. Ann N Y Acad Sci. 2015;1342:29–36. PMID: 25678404

Winer B, Ploss A. Breaking the species barrier for hepatitis delta virus. Hepatology. 2016;63(1):334–6. PMCID: PMC4899507