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Cytomegalovirus Infections

  • 1.
    Cook K, Tsopurashvili E, Needham J, Thompson S, Cristea I. Restructured membrane contacts rewire organelles for human cytomegalovirus infection. Nat Commun. 2022;13(1):4720. PMCID: PMC9366835
    Reference Link
  • 1.
    Tyl M, Betsinger C, Cristea I. Virus-host protein interactions as footprints of human cytomegalovirus replication. Curr Opin Virol. 2022;52:135–147. PMCID: PMC8844139
    Reference Link
  • 1.
    Betsinger C, Jankowski C, Hofstadter W, Federspiel J, Otter C, Beltran P, Cristea I. The human cytomegalovirus protein pUL13 targets mitochondrial cristae architecture to increase cellular respiration during infection. Proc Natl Acad Sci U S A. 2021;118(32). PMCID: PMC8364163
    Reference Link
  • 1.
    Sheng X, Cristea I. The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection. PLoS Pathog. 2021;17(4):e1009506. PMCID: PMC8078788
    Reference Link
  • 1.
    Naseri-Nosar P, Nogalski M, Shenk T. The aryl hydrocarbon receptor facilitates the human cytomegalovirus-mediated G1/S block to cell cycle progression. Proc Natl Acad Sci U S A. 2021;118(12). PMCID: PMC8000196
    Reference Link
  • 1.
    Nogalski M, Shenk T. HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement. Proc Natl Acad Sci U S A. 2020;117(50):31891–31901. PMCID: PMC7749351
    Reference Link
  • 1.
    Federspiel J, Cook K, Kennedy M, Venkatesh S, Otter C, Hofstadter W, Beltran P, Cristea I. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020;32(4):107943. PMCID: PMC8489195
    Reference Link
  • 1.
    Song B, Greco T, Lum K, Taber C, Cristea I. The DNA Sensor cGAS is Decorated by Acetylation and Phosphorylation Modifications in the Context of Immune Signaling. Mol Cell Proteomics. 2020;19(7):1193–1208. PMCID: PMC7338091
    Reference Link
  • 1.
    Hashimoto Y, Sheng X, Murray-Nerger L, Cristea I. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020;11(1):806. PMCID: PMC7010728
    Reference Link
  • 1.
    Chen S, Shenk T, Nogalski M. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019;116(38):18971–18982. PMCID: PMC6754545
    Reference Link
  • 1.
    Murray L, Sheng X, Cristea I. Orchestration of protein acetylation as a toggle for cellular defense and virus replication. Nat Commun. 2018;9(1):4967. PMCID: PMC6251895
    Reference Link
  • 1.
    Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proc Natl Acad Sci U S A. 2018;115(42):E9889-E9898. PMCID: PMC6196492
    Reference Link
  • 1.
    Beltran P, Cook K, Hashimoto Y, Galitzine C, Murray L, Vitek O, Cristea I. Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication. Cell Host Microbe. 2018;24(4):526–541.e7. PMCID: PMC6195127
    Reference Link
  • 1.
    Oberstein A, Shenk T. Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. Proc Natl Acad Sci U S A. 2017;114(39):E8244-E8253. PMCID: PMC5625929
    Reference Link
  • 1.
    Ziehr B, Lenarcic E, Vincent H, Cecil C, Garcia B, Shenk T, Moorman N. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 2015;15(12):1983–94. PMCID: PMC4492309
    Reference Link
  • 1.
    Beltran P, Mathias R, Cristea I. A Portrait of the Human Organelle Proteome In Space and Time during Cytomegalovirus Infection. Cell Syst. 2016;3(4):361–373.e6. PMCID: PMC5083158
    Reference Link
  • 1.
    Hwang J, Purdy J, Wu K, Rabinowitz J, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proc Natl Acad Sci U S A. 2014;111(52):E5706–15. PMCID: PMC4284536
    Reference Link
  • 1.
    Oberstein A, Perlman D, Shenk T, Terry L. Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. Proteomics. 2015;15(12):2006–22. PMCID: PMC4522931
    Reference Link

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