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1.Kennedy M, Tyl M, Betsinger C, Federspiel J, Sheng X, Arbuckle J, Kristie T, Cristea I. A TRUSTED targeted mass spectrometry assay for pan-herpesvirus protein detection. Cell Rep. 2022;39(6):110810. PMCID: PMC9245836 Reference Link
1.Tyl M, Betsinger C, Cristea I. Virus-host protein interactions as footprints of human cytomegalovirus replication. Curr Opin Virol. 2022;52:135–147. PMCID: PMC8844139 Reference Link
1.Betsinger C, Jankowski C, Hofstadter W, Federspiel J, Otter C, Beltran P, Cristea I. The human cytomegalovirus protein pUL13 targets mitochondrial cristae architecture to increase cellular respiration during infection. Proc Natl Acad Sci U S A. 2021;118(32). PMCID: PMC8364163 Reference Link
1.Sheng X, Cristea I. The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection. PLoS Pathog. 2021;17(4):e1009506. PMCID: PMC8078788 Reference Link
1.Naseri-Nosar P, Nogalski M, Shenk T. The aryl hydrocarbon receptor facilitates the human cytomegalovirus-mediated G1/S block to cell cycle progression. Proc Natl Acad Sci U S A. 2021;118(12). PMCID: PMC8000196 Reference Link
1.Howard T, Cristea I. Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective. Biomolecules. 2020;10(12). PMCID: PMC7761228 Reference Link
1.Federspiel J, Cook K, Kennedy M, Venkatesh S, Otter C, Hofstadter W, Beltran P, Cristea I. Mitochondria and Peroxisome Remodeling across Cytomegalovirus Infection Time Viewed through the Lens of Inter-ViSTA. Cell Rep. 2020;32(4):107943. PMCID: PMC8489195 Reference Link
1.Hashimoto Y, Sheng X, Murray-Nerger L, Cristea I. Temporal dynamics of protein complex formation and dissociation during human cytomegalovirus infection. Nat Commun. 2020;11(1):806. PMCID: PMC7010728 Reference Link
1.Chen S, Shenk T, Nogalski M. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019;116(38):18971–18982. PMCID: PMC6754545 Reference Link
1.Murray L, Sheng X, Cristea I. Orchestration of protein acetylation as a toggle for cellular defense and virus replication. Nat Commun. 2018;9(1):4967. PMCID: PMC6251895 Reference Link
1.Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proc Natl Acad Sci U S A. 2018;115(42):E9889-E9898. PMCID: PMC6196492 Reference Link
1.Beltran P, Cook K, Hashimoto Y, Galitzine C, Murray L, Vitek O, Cristea I. Infection-Induced Peroxisome Biogenesis Is a Metabolic Strategy for Herpesvirus Replication. Cell Host Microbe. 2018;24(4):526–541.e7. PMCID: PMC6195127 Reference Link
1.Oberstein A, Shenk T. Cellular responses to human cytomegalovirus infection: Induction of a mesenchymal-to-epithelial transition (MET) phenotype. Proc Natl Acad Sci U S A. 2017;114(39):E8244-E8253. PMCID: PMC5625929 Reference Link
1.Ziehr B, Lenarcic E, Vincent H, Cecil C, Garcia B, Shenk T, Moorman N. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 2015;15(12):1983–94. PMCID: PMC4492309 Reference Link
1.Diner B, Lum K, Toettcher J, Cristea I. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection. mBio. 2016;7(6). PMCID: PMC5111403 Reference Link
1.Hwang J, Purdy J, Wu K, Rabinowitz J, Shenk T. Estrogen-related receptor α is required for efficient human cytomegalovirus replication. Proc Natl Acad Sci U S A. 2014;111(52):E5706–15. PMCID: PMC4284536 Reference Link
1.Purdy J, Shenk T, Rabinowitz J. Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication. Cell Rep. 2015;10(8):1375–85. PMCID: PMC4354725 Reference Link
1.Oberstein A, Perlman D, Shenk T, Terry L. Human cytomegalovirus pUL97 kinase induces global changes in the infected cell phosphoproteome. Proteomics. 2015;15(12):2006–22. PMCID: PMC4522931 Reference Link