Yuan Y, Kong F, Xu H, Zhu A, Yan N, Yan C. Cryo-EM structure of human glucose transporter GLUT4. Nat Commun. 2022;13(1):2671. PMCID: PMC9106701

Toti K, Jimah J, Salmaso V, Hinshaw J, Jacobson K. Synthesis and Effect of Conformationally Locked Carbocyclic Guanine Nucleotides on Dynamin. Biomolecules. 2022;12(4). PMCID: PMC9031165

Doyle M, Jimah J, Dowdy T, Ohlemacher S, Larion M, Hinshaw J, Bernstein H. Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022;185(7):1143–1156.e13. PMCID: PMC8985213

Sochacki K, Heine B, Haber G, Jimah J, Prasai B, Alfonzo-Méndez M, Roberts A, Somasundaram A, Hinshaw J, Taraska J. The structure and spontaneous curvature of clathrin lattices at the plasma membrane. Dev Cell. 2021;56(8):1131–1146.e3. PMCID: PMC8081270

Gao S, Yao X, Yan N. Structure of human Ca2.2 channel blocked by the painkiller ziconotide. Nature. 2021;596(7870):143–147. PMCID: PMC8529174

Shen H, Yan N, Pan X. Structural determination of human Na1.4 and Na1.7 using single particle cryo-electron microscopy. Methods Enzymol. 2021;653:103–120. PMID: 34099168

Li Z, Jin X, Wu T, Huang G, Wu K, Lei J, Pan X, Yan N. Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na 1.5 by the Antiarrhythmic Drug Quinidine*. Angew Chem Int Ed Engl. 2021;60(20):11474–11480. PMID: 33684260

Li Z, Jin X, Wu T, Zhao X, Wang W, Lei J, Pan X, Yan N. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980460

Pan X, Li Z, Jin X, Zhao Y, Huang G, Huang X, Shen Z, Cao Y, Dong M, Lei J, Yan N. Comparative structural analysis of human Na1.1 and Na1.5 reveals mutational hotspots for sodium channelopathies. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980448

Yan R, Cao P, Song W, Qian H, Du X, Coates H, Zhao X, Li Y, Gao S, Gong X, Liu X, Sui J, Lei J, Yang H, Brown A, Zhou Q, Yan C, Yan N. A structure of human Scap bound to Insig-2 suggests how their interaction is regulated by sterols. Science. 2021;371(6533). PMID: 33446483

Gong D, Yan N, Ledford H. Structural Basis for the Modulation of Ryanodine Receptors. Trends Biochem Sci. 2021;46(6):489–501. PMID: 33353849

Pan Y, Ren Z, Gao S, Shen J, Wang L, Xu Z, Yu Y, Bachina P, Zhang H, Fan X, Laganowsky A, Yan N, Zhou M. Structural basis of ion transport and inhibition in ferroportin. Nat Commun. 2020;11(1):5686. PMCID: PMC7655804

Gao S, Yan N. Structural Basis of the Modulation of the Voltage-Gated Calcium Ion Channel Ca 1.1 by Dihydropyridine Compounds*. Angew Chem Int Ed Engl. 2021;60(6):3131–3137. PMCID: PMC7898392

Yao X, Fan X, Yan N. Cryo-EM analysis of a membrane protein embedded in the liposome. Proc Natl Acad Sci U S A. 2020;117(31):18497–18503. PMCID: PMC7414195

Gao S, Valinsky W, On N, Houlihan P, Qu Q, Liu L, Pan X, Clapham D, Yan N. Employing NaChBac for cryo-EM analysis of toxin action on voltage-gated Na channels in nanodisc. Proc Natl Acad Sci U S A. 2020;117(25):14187–14193. PMCID: PMC7322032

Wang L, Qian H, Nian Y, Han Y, Ren Z, Zhang H, Hu L, Prasad B, Laganowsky A, Yan N, Zhou M. Structure and mechanism of human diacylglycerol O-acyltransferase 1. Nature. 2020;581(7808):329–332. PMCID: PMC7255049

Qian H, Zhao X, Yan R, Yao X, Gao S, Sun X, Du X, Yang H, Wong C, Yan N. Structural basis for catalysis and substrate specificity of human ACAT1. Nature. 2020;581(7808):333–338. PMCID: 5093084

Zhao Y, Huang G, Wu J, Wu Q, Gao S, Yan Z, Lei J, Yan N. Molecular Basis for Ligand Modulation of a Mammalian Voltage-Gated Ca Channel. Cell. 2019;177(6):1495–1506.e12. PMID: 31150622

Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N. Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators. Proc Natl Acad Sci U S A. 2019;116(51):25575–25582. PMCID: PMC6926060

Zhao Y, Huang G, Wu Q, Wu K, Li R, Lei J, Pan X, Yan N. Cryo-EM structures of apo and antagonist-bound human Ca3.1. Nature. 2019;576(7787):492–497. PMCID: 18083096

Brose N, Brunger A, Cafiso D, Chapman E, Diao J, Hughson F, Jackson M, Jahn R, Lindau M, Ma C, Rizo J, Shin Y-K, Söllner T, Tamm L, Yoon T-Y, Zhang Y. Synaptic vesicle fusion: today and beyond. Nat Struct Mol Biol. 2019;26(8):663–668. PMID: 31384060

Gong D, Chi X, Wei J, Zhou G, Huang G, Zhang L, Wang R, Lei J, Chen S, Yan N. Modulation of cardiac ryanodine receptor 2 by calmodulin. Nature. 2019;572(7769):347–351. PMID: 31278385

Qian H, Cao P, Hu M, Gao S, Yan N, Gong X. Inhibition of tetrameric Patched1 by Sonic Hedgehog through an asymmetric paradigm. Nat Commun. 2019;10(1):2320. PMCID: PMC6534611

Shen H, Liu D, Wu K, Lei J, Yan N. Structures of human Na1.7 channel in complex with auxiliary subunits and animal toxins. Science. 2019;363(6433):1303–1308. PMID: 30765606

Pan X, Li Z, Huang X, Huang G, Gao S, Shen H, Liu L, Lei J, Yan N. Molecular basis for pore blockade of human Na channel Na1.2 by the μ-conotoxin KIIIA. Science. 2019;363(6433):1309–1313. PMID: 30765605

Yan R, Qian H, Lukmantara I, Gao M, Du X, Yan N, Yang H. Human SEIPIN Binds Anionic Phospholipids. Dev Cell. 2018;47(2):248–256.e4. PMID: 30293840

Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N. Structure of the human voltage-gated sodium channel Na1.4 in complex with β1. Science. 2018;362(6412). PMID: 30190309

Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith J, K Y Chin Y, Lei J, Zhou Q, King G, Yan N. Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science. 2018;362(6412). PMID: 30049784

Gong X, Qian H, Cao P, Zhao X, Zhou Q, Lei J, Yan N. Structural basis for the recognition of Sonic Hedgehog by human Patched1. Science. 2018;361(6402). PMID: 29954986

Yan Z, Zhou Q, Wang L, Wu J, Zhao Y, Huang G, Peng W, Shen H, Lei J, Yan N. Structure of the Na1.4-β1 Complex from Electric Eel. Cell. 2017;170(3):470–482.e11. PMID: 28735751

Yan Z, Bai X, Yan C, Wu J, Li Z, Xie T, Peng W, Yin C, Li X, Scheres S, Shi Y, Yan N. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015;517(7532):50–55. PMCID: PMC4338550

Fernández-Capetillo Óscar, Yan N, Dionne J, Bassett D, Sebastian S, Hendon C, Schlichting H, Baker M. Hopes for the year ahead. Nature. 2015;517(7532):111–3. PMID: 25568916

Wu J, Yan Z, Li Z, Yan C, Lu S, Dong M, Yan N. Structure of the voltage-gated calcium channel Cav1.1 complex. Science. 2015;350(6267):aad2395. PMID: 26680202

Bai X-C, Yan Z, Wu J, Li Z, Yan N. The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening. Cell Res. 2016;26(9):995–1006. PMCID: PMC5034110

Peng W, Shen H, Wu J, Guo W, Pan X, Wang R, Chen S, Yan N. Structural basis for the gating mechanism of the type 2 ryanodine receptor RyR2. Science. 2016;354(6310). PMID: 27708056

Gong X, Qian H, Shao W, Li J, Wu J, Liu J-J, Li W, Wang H-W, Espenshade P, Yan N. Complex structure of the fission yeast SREBP-SCAP binding domains reveals an oligomeric organization. Cell Res. 2016;26(11):1197–1211. PMCID: PMC5099872

Shen H, Zhou Q, Pan X, Li Z, Wu J, Yan N. Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science. 2017;355(6328). PMID: 28183995

Qian H, Zhao X, Cao P, Lei J, Yan N, Gong X. Structure of the Human Lipid Exporter ABCA1. Cell. 2017;169(7):1228–1239.e10. PMID: 28602350

Hogue I, Jean J, Esteves A, Tanneti N, Scherer J, Enquist L. Functional Carboxy-Terminal Fluorescent Protein Fusion to Pseudorabies Virus Small Capsid Protein VP26. J Virol. 2018;92(1). PMCID: PMC5730785

Rosenzweig E, Xu B, Cuellar L, Martinez-Sanchez A, Schaffer M, Strauss M, Cartwright H, Ronceray P, Plitzko J, Förster F, Wingreen N, Engel B, Mackinder L, Jonikas M. The Eukaryotic CO-Concentrating Organelle Is Liquid-like and Exhibits Dynamic Reorganization. Cell. 2017;171(1):148–162.e19. PMCID: PMC5671343

Lynch E, Hicks D, Shepherd M, Endrizzi J, Maker A, Hansen J, Barry R, Gitai Z, Baldwin E, Kollman J. Human CTP synthase filament structure reveals the active enzyme conformation. Nat Struct Mol Biol. 2017;24(6):507–514. PMCID: PMC5472220

Hagen C, Dent K, Zeev-Ben-Mordehai T, Grange M, Bosse J, Whittle C, Klupp B, Siebert A, Vasishtan D, Bäuerlein F, Cheleski J, Werner S, Guttmann P, Rehbein S, Henzler K, Demmerle J, Adler B, Koszinowski U, Schermelleh L, Schneider G, Enquist L, Plitzko J, Mettenleiter T, Grünewald K. Structural Basis of Vesicle Formation at the Inner Nuclear Membrane. Cell. 2015;163(7):1692–701. PMCID: PMC4701712