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Cells, Cultured

  • 1.
    Lim A, Menegatti S, Bustamante J, Le Bourhis L, Allez M, Rogge L, Casanova J-L, Yssel H, Di Santo J. IL-12 drives functional plasticity of human group 2 innate lymphoid cells. J Exp Med. 2016;213(4):569–83. PMCID: PMC4821648
    Reference Link
  • 1.
    Jaslove J, Goodwin K, Sundarakrishnan A, Spurlin J, Mao S, Košmrlj A, Nelson C. Transmural pressure signals through retinoic acid to regulate lung branching. Development. 2022;149(2). PMCID: PMC8917413
    Reference Link
  • 1.
    Farahani P, Lemke S, Dine E, Uribe G, Toettcher J, Nelson C. Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021;37(13):110181. PMCID: PMC8756379
    Reference Link
  • 1.
    Sharma A, Schwarzbauer J. Differential Regulation of Neurite Outgrowth and Growth Cone Morphology by 3D Fibronectin and Fibronectin-Collagen Extracellular Matrices. Mol Neurobiol. 2022;59(2):1112–1123. PMCID: PMC8858852
    Reference Link
  • 1.
    Howe R, Kelly M, Jimah J, Hodge D, Odom A. Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum. Eukaryot Cell. 2013;12(2):215–23. PMCID: PMC3571303
    Reference Link
  • 1.
    Minhas P, Latif-Hernandez A, McReynolds M, Durairaj A, Wang Q, Rubin A, Joshi A, He J, Gauba E, Liu L, Wang C, Linde M, Sugiura Y, Moon P, Majeti R, Suematsu M, Mochly-Rosen D, Weissman I, Longo F, Rabinowitz J, Andreasson K. Restoring metabolism of myeloid cells reverses cognitive decline in ageing. Nature. 2021;590(7844):122–128. PMCID: PMC8274816
    Reference Link
  • 1.
    Van Cleemput J, Koyuncu O, Laval K, Engel E, Enquist L. CRISPR/Cas9-Constructed Pseudorabies Virus Mutants Reveal the Importance of UL13 in Alphaherpesvirus Escape from Genome Silencing. J Virol. 2021;95(6). PMCID: PMC8094956
    Reference Link
  • 1.
    Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin J, Jaschinski F, Zhou T, Klar R, Kang Y. Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis. Cancer Res. 2021;81(4):1014–1025. PMCID: PMC8026491
    Reference Link
  • 1.
    Zhang Y, Xu Y, Lu W, Ghergurovich J, Guo L, Blair I, Rabinowitz J, Yang X. Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation. Cell Metab. 2021;33(1):94–109.e8. PMCID: PMC7846267
    Reference Link
  • 1.
    Pham K, Huynh D, Le L, Delitto D, Yang L, Huang J, Kang Y, Steinberg M, Li J, Zhang L, Liu D, Tang M-S, Liu C, Wang H. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Lett. 2020;491:132–145. PMCID: PMC9703643
    Reference Link
  • 1.
    Garrison C, Singh-Varma A, Pastino A, Steele J, Kohn J, Murthy S, Schwarzbauer J. A multilayered scaffold for regeneration of smooth muscle and connective tissue layers. J Biomed Mater Res A. 2021;109(5):733–744. PMCID: PMC7855544
    Reference Link
  • 1.
    Huang H, Koyuncu O, Enquist L. Pseudorabies Virus Infection Accelerates Degradation of the Kinesin-3 Motor KIF1A. J Virol. 2020;94(9). PMCID: PMC7163149
    Reference Link
  • 1.
    Chi X, Gong D, Ren K, Zhou G, Huang G, Lei J, Zhou Q, Yan N. Molecular basis for allosteric regulation of the type 2 ryanodine receptor channel gating by key modulators. Proc Natl Acad Sci U S A. 2019;116(51):25575–25582. PMCID: PMC6926060
    Reference Link
  • 1.
    Gaska J, Parsons L, Balev M, Cirincione A, Wang W, Schwartz R, Ploss A. Conservation of cell-intrinsic immune responses in diverse nonhuman primate species. Life Sci Alliance. 2019;2(5). PMCID: PMC6814850
    Reference Link
  • 1.
    Lum K, Howard T, Pan C, Cristea I. Charge-Mediated Pyrin Oligomerization Nucleates Antiviral IFI16 Sensing of Herpesvirus DNA. mBio. 2019;10(4). PMCID: PMC6650555
    Reference Link
  • 1.
    Minhas P, Liu L, Moon P, Joshi A, Dove C, Mhatre S, Contrepois K, Wang Q, Lee B, Coronado M, Bernstein D, Snyder M, Migaud M, Majeti R, Mochly-Rosen D, Rabinowitz J, Andreasson K. Macrophage de novo NAD synthesis specifies immune function in aging and inflammation. Nat Immunol. 2019;20(1):50–63. PMCID: PMC6768398
    Reference Link
  • 1.
    Lee Y-S, Wong A, Tadych A, Hartmann B, Park C, DeJesus V, Ramos I, Zaslavsky E, Sealfon S, Troyanskaya O. Interpretation of an individual functional genomics experiment guided by massive public data. Nat Methods. 2018;15(12):1049–1052. PMCID: PMC6941785
    Reference Link
  • 1.
    Rodriguez A, Ducker G, Billingham L, Martinez C, Mainolfi N, Suri V, Friedman A, Manfredi M, Weinberg S, Rabinowitz J, Chandel N. Serine Metabolism Supports Macrophage IL-1β Production. Cell Metab. 2019;29(4):1003–1011.e4. PMCID: PMC6447453
    Reference Link
  • 1.
    Wu K, Oberstein A, Wang W, Shenk T. Role of PDGF receptor-α during human cytomegalovirus entry into fibroblasts. Proc Natl Acad Sci U S A. 2018;115(42):E9889-E9898. PMCID: PMC6196492
    Reference Link
  • 1.
    Fernández J, Webb C, Rouzard K, Healy J, Tamura M, Voronkov M, Huber K, Stock J, Stock M, Gordon J, Pérez E. SIG1459: A novel phytyl-cysteine derived TLR2 modulator with in vitro and clinical anti-acne activity. Exp Dermatol. 2018;27(9):993–999. PMID: 29797368
    Reference Link
  • 1.
    Harris A, Siggers P, Corrochano S, Warr N, Sagar D, Grimes D, Suzuki M, Burdine R, Cong F, Koo B-K, Clevers H, Stévant I, Nef S, Wells S, Brauner R, Ben Rhouma B, Belguith N, Eozenou C, Bignon-Topalovic J, Bashamboo A, McElreavey K, Greenfield A. ZNRF3 functions in mammalian sex determination by inhibiting canonical WNT signaling. Proc Natl Acad Sci U S A. 2018;115(21):5474–5479. PMCID: PMC6003506
    Reference Link
  • 1.
    Miller R, Shi Y, Lu W, Pirman D, Jatkar A, Blatnik M, Wu H, Cárdenas C, Wan M, Foskett K, Park J, Zhang Y, Holland W, Rabinowitz J, Birnbaum M. Targeting hepatic glutaminase activity to ameliorate hyperglycemia. Nat Med. 2018;24(4):518–524. PMCID: PMC6089616
    Reference Link
  • 1.
    Han S, Pang M-F, Nelson C. Substratum stiffness tunes proliferation downstream of Wnt3a in part by regulating integrin-linked kinase and frizzled-1. J Cell Sci. 2018;131(8). PMCID: PMC5963841
    Reference Link
  • 1.
    Harris G, Raitman I, Schwarzbauer J. Cell-derived decellularized extracellular matrices. Methods Cell Biol. 2018;143:97–114. PMCID: PMC5995326
    Reference Link
  • 1.
    Nimgaonkar I, Ding Q, Schwartz R, Ploss A. Hepatitis E virus: advances and challenges. Nat Rev Gastroenterol Hepatol. 2018;15(2):96–110. PMID: 29162935
    Reference Link
  • 1.
    Koyuncu O, MacGibeny M, Hogue I, Enquist L. Compartmented neuronal cultures reveal two distinct mechanisms for alpha herpesvirus escape from genome silencing. PLoS Pathog. 2017;13(10):e1006608. PMCID: PMC5658187
    Reference Link
  • 1.
    Hogue I, Jean J, Esteves A, Tanneti N, Scherer J, Enquist L. Functional Carboxy-Terminal Fluorescent Protein Fusion to Pseudorabies Virus Small Capsid Protein VP26. J Virol. 2018;92(1). PMCID: PMC5730785
    Reference Link
  • 1.
    Kim H, Raffler J, Lu W, Lee J-J, Abbey D, Saleheen D, Rabinowitz J, Bennett M, Hand N, Brown C, Rader D. Fine Mapping and Functional Analysis Reveal a Role of SLC22A1 in Acylcarnitine Transport. Am J Hum Genet. 2017;101(4):489–502. PMCID: PMC5630162
    Reference Link
  • 1.
    Lu Y, Xie S, Zhang W, Zhang C, Gao C, Sun Q, Cai Y, Xu Z, Xiao M, Xu Y, Huang X, Wu X, Liu W, Wang F, Kang Y, Zhou T. Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis. Cell Res. 2017;27(12):1422–1440. PMCID: PMC5717399
    Reference Link
  • 1.
    Pujol F, Hodgson T, Martinez-Corral I, Prats A-C, Devenport D, Takeichi M, Genot E, Mäkinen T, Francis-West P, Garmy-Susini B, Tatin F. Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37(9):1732–1735. PMID: 28705793
    Reference Link
  • 1.
    Winer B, Huang T, Pludwinski E, Heller B, Wojcik F, Lipkowitz G, Parekh A, Cho C, Shrirao A, Muir T, Novik E, Ploss A. Long-term hepatitis B infection in a scalable hepatic co-culture system. Nat Commun. 2017;8(1):125. PMCID: PMC5527081
    Reference Link
  • 1.
    Lu W, Wang L, Chen L, Hui S, Rabinowitz J. Extraction and Quantitation of Nicotinamide Adenine Dinucleotide Redox Cofactors. Antioxid Redox Signal. 2018;28(3):167–179. PMCID: PMC5737638
    Reference Link
  • 1.
    Rogers W, Goyal Y, Yamaya K, Shvartsman S, Levine M. Uncoupling neurogenic gene networks in the embryo. Genes Dev. 2017;31(7):634–638. PMCID: PMC5411704
    Reference Link
  • 1.
    Arora N, Alsous J, Guggenheim J, Mak M, Munera J, Wells J, Kamm R, Asada H, Shvartsman S, Griffith L. A process engineering approach to increase organoid yield. Development. 2017;144(6):1128–1136. PMCID: PMC5358111
    Reference Link
  • 1.
    Lim B, Dsilva C, Kevrekidis I, Shvartsman S. Reconstructing ERK Signaling in the Drosophila Embryo from Fixed Images. Methods Mol Biol. 2017;1487:337–351. PMCID: PMC6557116
    Reference Link
  • 1.
    Ziehr B, Lenarcic E, Vincent H, Cecil C, Garcia B, Shenk T, Moorman N. Human cytomegalovirus TRS1 protein associates with the 7-methylguanosine mRNA cap and facilitates translation. Proteomics. 2015;15(12):1983–94. PMCID: PMC4492309
    Reference Link
  • 1.
    Rowles D, Tsai Y-C, Greco T, Lin A, Li M, Yeh J, Cristea I. DNA methyltransferase DNMT3A associates with viral proteins and impacts HSV-1 infection. Proteomics. 2015;15(12):1968–82. PMCID: PMC4550099
    Reference Link
  • 1.
    Mathias R, Greco T, Cristea I. Identification of Sirtuin4 (SIRT4) Protein Interactions: Uncovering Candidate Acyl-Modified Mitochondrial Substrates and Enzymatic Regulators. Methods Mol Biol. 2016;1436:213–39. PMCID: PMC4919573
    Reference Link
  • 1.
    Diner B, Lum K, Javitt A, Cristea I. Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression. Mol Cell Proteomics. 2015;14(9):2341–56. PMCID: PMC4563720
    Reference Link
  • 1.
    Prentice J, Marre O, Ioffe M, Loback A, Tkačik G, Berry M. Error-Robust Modes of the Retinal Population Code. PLoS Comput Biol. 2016;12(11):e1005148. PMCID: PMC5113862
    Reference Link
  • 1.
    Piotrowski-Daspit A, Simi A, Pang M-F, Tien J, Nelson C. A 3D Culture Model to Study How Fluid Pressure and Flow Affect the Behavior of Aggregates of Epithelial Cells. Methods Mol Biol. 2017;1501:245–257. PMID: 27796957
    Reference Link
  • 1.
    Diner B, Lum K, Toettcher J, Cristea I. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection. mBio. 2016;7(6). PMCID: PMC5111403
    Reference Link
  • 1.
    Christensen M, Jensen S, Miettinen J, Luecke S, Prabakaran T, Reinert L, Mettenleiter T, Chen Z, Knipe D, Sandri-Goldin R, Enquist L, Hartmann R, Mogensen T, Rice S, Nyman T, Matikainen S, Paludan S. HSV-1 ICP27 targets the TBK1-activated STING signalsome to inhibit virus-induced type I IFN expression. EMBO J. 2016;35(13):1385–99. PMCID: PMC4931188
    Reference Link
  • 1.
    Feric M, Vaidya N, Harmon T, Mitrea D, Zhu L, Richardson T, Kriwacki R, Pappu R, Brangwynne C. Coexisting Liquid Phases Underlie Nucleolar Subcompartments. Cell. 2016;165(7):1686–1697. PMCID: PMC5127388
    Reference Link
  • 1.
    Pang M-F, Georgoudaki A-M, Lambut L, Johansson J, Tabor V, Hagikura K, Jin Y, Jansson M, Alexander J, Nelson C, Jakobsson L, Betsholtz C, Sund M, Karlsson M, Fuxe J. TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene. 2016;35(6):748–60. PMCID: PMC4753256
    Reference Link
  • 1.
    Gjorevski N, Piotrowski A, Varner V, Nelson C. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep. 2015;5:11458. PMCID: PMC4499882
    Reference Link
  • 1.
    Budayeva H, Cristea I. Human Sirtuin 2 Localization, Transient Interactions, and Impact on the Proteome Point to Its Role in Intracellular Trafficking. Mol Cell Proteomics. 2016;15(10):3107–3125. PMCID: PMC5054338
    Reference Link
  • 1.
    Siedlik M, Varner V, Nelson C. Pushing, pulling, and squeezing our way to understanding mechanotransduction. Methods. 2016;94:4–12. PMCID: PMC4761538
    Reference Link
  • 1.
    Kim H, Pang M-F, Varner V, Kojima L, Miller E, Radisky D, Nelson C. Localized Smooth Muscle Differentiation Is Essential for Epithelial Bifurcation during Branching Morphogenesis of the Mammalian Lung. Dev Cell. 2015;34(6):719–26. PMCID: PMC4589145
    Reference Link
  • 1.
    Devenport D, Fuchs E. Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008;10(11):1257–68. PMCID: PMC2607065
    Reference Link

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