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Cell Nucleus

  • 1.
    Nguyen T, Costa E, Deibert T, Reyes J, Keber F, Tomschik M, Stadlmeier M, Gupta M, Kumar C, Cruz E, Amodeo A, Gatlin J, Wühr M. Differential nuclear import sets the timing of protein access to the embryonic genome. Nat Commun. 2022;13(1):5887. PMCID: PMC9537182
    Reference Link
  • 1.
    Murray-Nerger L, Cristea I. Lamin post-translational modifications: emerging toggles of nuclear organization and function. Trends Biochem Sci. 2021;46(10):832–847. PMCID: PMC8793286
    Reference Link
  • 1.
    Zhang Y, Lee D, Meir Y, Brangwynne C, Wingreen N. Mechanical Frustration of Phase Separation in the Cell Nucleus by Chromatin. Phys Rev Lett. 2021;126(25):258102. PMCID: PMC8604804
    Reference Link
  • 1.
    Strom A, Biggs R, Banigan E, Wang X, Chiu K, Herman C, Collado J, Yue F, Politz J, Tait L, Scalzo D, Telling A, Groudine M, Brangwynne C, Marko J, Stephens A. HP1α is a chromatin crosslinker that controls nuclear and mitotic chromosome mechanics. Elife. 2021;10. PMCID: PMC8233041
    Reference Link
  • 1.
    Nollmann M, Bennabi I, Götz M, Gregor T. The Impact of Space and Time on the Functional Output of the Genome. Cold Spring Harb Perspect Biol. 2022;14(4). PMCID: PMC8733053
    Reference Link
  • 1.
    Murray-Nerger L, Justice J, Rekapalli P, Hutton J, Cristea I. Lamin B1 acetylation slows the G1 to S cell cycle transition through inhibition of DNA repair. Nucleic Acids Res. 2021;49(4):2044–2064. PMCID: PMC7913768
    Reference Link
  • 1.
    Silver B, Wolf A, Lee J, Pang M-F, Nelson C. Epithelial tissue geometry directs emergence of bioelectric field and pattern of proliferation. Mol Biol Cell. 2020;31(16):1691–1702. PMCID: PMC7521849
    Reference Link
  • 1.
    Garcia D, Leach R, Wadsworth G, Choudhary K, Li H, Aviran S, Kim H, Zakian V. Stability and nuclear localization of yeast telomerase depend on protein components of RNase P/MRP. Nat Commun. 2020;11(1):2173. PMCID: PMC7195438
    Reference Link
  • 1.
    Keenan S, Blythe S, Marmion R, Djabrayan N, Wieschaus E, Shvartsman S. Rapid Dynamics of Signal-Dependent Transcriptional Repression by Capicua. Dev Cell. 2020;52(6):794–801.e4. PMCID: PMC7161736
    Reference Link
  • 1.
    Strom A, Brangwynne C. The liquid nucleome - phase transitions in the nucleus at a glance. J Cell Sci. 2019;132(22). PMCID: PMC6899023
    Reference Link
  • 1.
    Nguyen T, Pappireddi N, Wühr M. Proteomics of nucleocytoplasmic partitioning. Curr Opin Chem Biol. 2019;48:55–63. PMCID: PMC6382543
    Reference Link
  • 1.
    Murray L, Sheng X, Cristea I. Orchestration of protein acetylation as a toggle for cellular defense and virus replication. Nat Commun. 2018;9(1):4967. PMCID: PMC6251895
    Reference Link
  • 1.
    Geronimo C, Singh S, Galletto R, Zakian V. The signature motif of the Saccharomyces cerevisiae Pif1 DNA helicase is essential in vivo for mitochondrial and nuclear functions and in vitro for ATPase activity. Nucleic Acids Res. 2018;46(16):8357–8370. PMCID: PMC6144861
    Reference Link
  • 1.
    Lee G, Zheng Y, Cho S, Jang C, England C, Dempsey J, Yu Y, Liu X, He L, Cavaliere P, Chavez A, Zhang E, Isik M, Couvillon A, Dephoure N, Blackwell K, Yu J, Rabinowitz J, Cantley L, Blenis J. Post-transcriptional Regulation of De Novo Lipogenesis by mTORC1-S6K1-SRPK2 Signaling. Cell. 2017;171(7):1545–1558.e18. PMCID: PMC5920692
    Reference Link
  • 1.
    He W, Brumos J, Li H, Ji Y, Ke M, Gong X, Zeng Q, Li W, Zhang X, An F, Wen X, Li P, Chu J, Sun X, Yan C, Yan N, Xie D-Y, Raikhel N, Yang Z, Stepanova A, Alonso J, Guo H. A small-molecule screen identifies L-kynurenine as a competitive inhibitor of TAA1/TAR activity in ethylene-directed auxin biosynthesis and root growth in Arabidopsis. Plant Cell. 2011;23(11):3944–60. PMCID: PMC3246337
    Reference Link
  • 1.
    Lu Y, Xie S, Zhang W, Zhang C, Gao C, Sun Q, Cai Y, Xu Z, Xiao M, Xu Y, Huang X, Wu X, Liu W, Wang F, Kang Y, Zhou T. Twa1/Gid8 is a β-catenin nuclear retention factor in Wnt signaling and colorectal tumorigenesis. Cell Res. 2017;27(12):1422–1440. PMCID: PMC5717399
    Reference Link
  • 1.
    Moloughney J, Kim P, Vega-Cotto N, Wu C-C, Zhang S, Adlam M, Lynch T, Chou P-C, Rabinowitz J, Werlen G, Jacinto E. mTORC2 Responds to Glutamine Catabolite Levels to Modulate the Hexosamine Biosynthesis Enzyme GFAT1. Mol Cell. 2016;63(5):811–26. PMCID: PMC5006067
    Reference Link
  • 1.
    Crow M, Cristea I. Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation. Mol Cell Proteomics. 2017;16(4 suppl 1):S200-S214. PMCID: PMC5393386
    Reference Link
  • 1.
    Guise A, Cristea I. Approaches for Studying the Subcellular Localization, Interactions, and Regulation of Histone Deacetylase 5 (HDAC5). Methods Mol Biol. 2016;1436:47–84. PMCID: PMC5644287
    Reference Link
  • 1.
    Blythe S, Wieschaus E. Establishment and maintenance of heritable chromatin structure during early embryogenesis. Elife. 2016;5. PMCID: PMC5156528
    Reference Link
  • 1.
    Diner B, Lum K, Toettcher J, Cristea I. Viral DNA Sensors IFI16 and Cyclic GMP-AMP Synthase Possess Distinct Functions in Regulating Viral Gene Expression, Immune Defenses, and Apoptotic Responses during Herpesvirus Infection. mBio. 2016;7(6). PMCID: PMC5111403
    Reference Link
  • 1.
    King M, Petry S. Visualizing and Analyzing Branching Microtubule Nucleation Using Meiotic Xenopus Egg Extracts and TIRF Microscopy. Methods Mol Biol. 2016;1413:77–85. PMCID: PMC5016078
    Reference Link
  • 1.
    Diner B, Li T, Greco T, Crow M, Fuesler J, Wang J, Cristea I. The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA. Mol Syst Biol. 2015;11(1):787. PMCID: PMC4358659
    Reference Link
  • 1.
    Berry J, Weber S, Vaidya N, Haataja M, Brangwynne C. RNA transcription modulates phase transition-driven nuclear body assembly. Proc Natl Acad Sci U S A. 2015;112(38):E5237–45. PMCID: PMC4586886
    Reference Link
  • 1.
    Bosse J, Hogue I, Feric M, Thiberge S, Sodeik B, Brangwynne C, Enquist L. Remodeling nuclear architecture allows efficient transport of herpesvirus capsids by diffusion. Proc Natl Acad Sci U S A. 2015;112(42):E5725–33. PMCID: PMC4620878
    Reference Link
  • 1.
    Feric M, Broedersz C, Brangwynne C. Soft viscoelastic properties of nuclear actin age oocytes due to gravitational creep. Sci Rep. 2015;5:16607. PMCID: PMC4649616
    Reference Link
  • 1.
    Little S, Sinsimer K, Lee J, Wieschaus E, Gavis E. Independent and coordinate trafficking of single Drosophila germ plasm mRNAs. Nat Cell Biol. 2015;17(5):558–68. PMCID: PMC4417036
    Reference Link
  • 1.
    Bothma J, Garcia H, Esposito E, Schlissel G, Gregor T, Levine M. Dynamic regulation of eve stripe 2 expression reveals transcriptional bursts in living Drosophila embryos. Proc Natl Acad Sci U S A. 2014;111(29):10598–603. PMCID: PMC4115566
    Reference Link
  • 1.
    Wühr M, Güttler T, Peshkin L, McAlister G, Sonnett M, Ishihara K, Groen A, Presler M, Erickson B, Mitchison T, Kirschner M, Gygi S. The Nuclear Proteome of a Vertebrate. Curr Biol. 2015;25(20):2663–71. PMCID: PMC4618192
    Reference Link
  • 1.
    Kim C, Miri A, Leung L, Berndt A, Mourrain P, Tank D, Burdine R. Prolonged, brain-wide expression of nuclear-localized GCaMP3 for functional circuit mapping. Front Neural Circuits. 2014;8:138. PMCID: PMC4244806
    Reference Link

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