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Cell Movement

  • 1.
    LaChance J, Suh K, Clausen J, Cohen D. Learning the rules of collective cell migration using deep attention networks. PLoS Comput Biol. 2022;18(4):e1009293. PMCID: PMC9106212
    Reference Link
  • 1.
    Farahani P, Lemke S, Dine E, Uribe G, Toettcher J, Nelson C. Substratum stiffness regulates Erk signaling dynamics through receptor-level control. Cell Rep. 2021;37(13):110181. PMCID: PMC8756379
    Reference Link
  • 1.
    Zajdel T, Shim G, Cohen D. Come together: On-chip bioelectric wound closure. Biosens Bioelectron. 2021;192:113479. PMCID: PMC8453109
    Reference Link
  • 1.
    Shim G, Devenport D, Cohen D. Overriding native cell coordination enhances external programming of collective cell migration. Proc Natl Acad Sci U S A. 2021;118(29). PMCID: PMC8307614
    Reference Link
  • 1.
    Esposito M, Fang C, Cook K, Park N, Wei Y, Spadazzi C, Bracha D, Gunaratna R, Laevsky G, DeCoste C, Slabodkin H, Brangwynne C, Cristea I, Kang Y. TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis. Nat Cell Biol. 2021;23(3):257–267. PMCID: PMC7970447
    Reference Link
  • 1.
    Kilinc A, Han S, Barrett L, Anandasivam N, Nelson C. Integrin-linked kinase tunes cell-cell and cell-matrix adhesions to regulate the switch between apoptosis and EMT downstream of TGFβ1. Mol Biol Cell. 2021;32(5):402–412. PMCID: PMC8098849
    Reference Link
  • 1.
    Nogalski M, Shenk T. HSATII RNA is induced via a noncanonical ATM-regulated DNA damage response pathway and promotes tumor cell proliferation and movement. Proc Natl Acad Sci U S A. 2020;117(50):31891–31901. PMCID: PMC7749351
    Reference Link
  • 1.
    Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin J, Jaschinski F, Zhou T, Klar R, Kang Y. Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis. Cancer Res. 2021;81(4):1014–1025. PMCID: PMC8026491
    Reference Link
  • 1.
    Li W, Shen M, Jiang Y-Z, Zhang R, Zheng H, Wei Y, Shao Z-M, Kang Y. Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2. Genes Dev. 2020;34(19-20):1310–1315. PMCID: PMC7528704
    Reference Link
  • 1.
    Fan H, Wang X, Li W, Shen M, Wei Y, Zheng H, Kang Y. ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP. Genes Dev. 2020;34(19-20):1359–1372. PMCID: PMC7528707
    Reference Link
  • 1.
    Pham K, Huynh D, Le L, Delitto D, Yang L, Huang J, Kang Y, Steinberg M, Li J, Zhang L, Liu D, Tang M-S, Liu C, Wang H. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Lett. 2020;491:132–145. PMCID: PMC9703643
    Reference Link
  • 1.
    Garrison C, Singh-Varma A, Pastino A, Steele J, Kohn J, Murthy S, Schwarzbauer J. A multilayered scaffold for regeneration of smooth muscle and connective tissue layers. J Biomed Mater Res A. 2021;109(5):733–744. PMCID: PMC7855544
    Reference Link
  • 1.
    Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford H, Fuxe J, de Herreros A, Goodall G, Hadjantonakis A-K, Huang R, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore G, Mani S, Massagué J, Mayor R, McClay D, Mostov K, Newgreen D, Nieto A, Puisieux A, Runyan R, Savagner P, Stanger B, Stemmler M, Takahashi Y, Takeichi M, Theveneau E, Thiery J, Thompson E, Weinberg R, Williams E, Xing J, Zhou B, Sheng G, EMT International Association (TEMTIA). Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020;21(6):341–352. PMCID: PMC7250738
    Reference Link
  • 1.
    Eichler C, Hakes A, Hull B, Gavis E. Compartmentalized degradation in the germ plasm safeguards germline development. Elife. 2020;9. PMCID: PMC6986870
    Reference Link
  • 1.
    Chen S, Shenk T, Nogalski M. P2Y2 purinergic receptor modulates virus yield, calcium homeostasis, and cell motility in human cytomegalovirus-infected cells. Proc Natl Acad Sci U S A. 2019;116(38):18971–18982. PMCID: PMC6754545
    Reference Link
  • 1.
    Liu G, Patch A, Bahar F, Yllanes D, Welch R, Marchetti C, Thutupalli S, Shaevitz J. Self-Driven Phase Transitions Drive Myxococcus xanthus Fruiting Body Formation. Phys Rev Lett. 2019;122(24):248102. PMID: 31322369
    Reference Link
  • 1.
    Bialistoky T, Manry D, Smith P, Ng C, Kim Y, Zamir S, Moyal V, Kalifa R, Schedl P, Gerlitz O, Deshpande G. Functional analysis of Niemann-Pick disease type C family protein, NPC1a, in . Development. 2019;146(10). PMCID: PMC6550021
    Reference Link
  • 1.
    Aiello N, Kang Y. Context-dependent EMT programs in cancer metastasis. J Exp Med. 2019;216(5):1016–1026. PMCID: PMC6504222
    Reference Link
  • 1.
    Esposito M, Mondal N, Greco T, Wei Y, Spadazzi C, Lin S-C, Zheng H, Cheung C, Magnani J, Lin S-H, Cristea I, Sackstein R, Kang Y. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019;21(5):627–639. PMCID: PMC6556210
    Reference Link
  • 1.
    Nogalski M, Solovyov A, Kulkarni A, Desai N, Oberstein A, Levine A, Ting D, Shenk T, Greenbaum B. A tumor-specific endogenous repetitive element is induced by herpesviruses. Nat Commun. 2019;10(1):90. PMCID: PMC6327058
    Reference Link
  • 1.
    Shen M, Jiang Y-Z, Wei Y, Ell B, Sheng X, Esposito M, Kang J, Hang X, Zheng H, Rowicki M, Zhang L, Shih W, Celià-Terrassa T, Liu Y, Cristea I, Shao Z-M, Kang Y. Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling. Cancer Cell. 2019;35(1):64–80.e7. PMID: 30612941
    Reference Link
  • 1.
    Simi A, Pang M-F, Nelson C. Extracellular Matrix Stiffness Exists in a Feedback Loop that Drives Tumor Progression. Adv Exp Med Biol. 2018;1092:57–67. PMID: 30368748
    Reference Link
  • 1.
    Cetera M, Leybova L, Joyce B, Devenport D. Counter-rotational cell flows drive morphological and cell fate asymmetries in mammalian hair follicles. Nat Cell Biol. 2018;20(5):541–552. PMCID: PMC6065250
    Reference Link
  • 1.
    Celià-Terrassa T, Kang Y. Metastatic niche functions and therapeutic opportunities. Nat Cell Biol. 2018;20(8):868–877. PMCID: 4161226
    Reference Link
  • 1.
    Harris G, Raitman I, Schwarzbauer J. Cell-derived decellularized extracellular matrices. Methods Cell Biol. 2018;143:97–114. PMCID: PMC5995326
    Reference Link
  • 1.
    Alečković M, Wei Y, LeRoy G, Sidoli S, Liu D, Garcia B, Kang Y. Identification of Nidogen 1 as a lung metastasis protein through secretome analysis. Genes Dev. 2017;31(14):1439–1455. PMCID: PMC5588926
    Reference Link
  • 1.
    Piotrowski-Daspit A, Nerger B, Wolf A, Sundaresan S, Nelson C. Dynamics of Tissue-Induced Alignment of Fibrous Extracellular Matrix. Biophys J. 2017;113(3):702–713. PMCID: PMC5550306
    Reference Link
  • 1.
    Pujol F, Hodgson T, Martinez-Corral I, Prats A-C, Devenport D, Takeichi M, Genot E, Mäkinen T, Francis-West P, Garmy-Susini B, Tatin F. Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report. Arterioscler Thromb Vasc Biol. 2017;37(9):1732–1735. PMID: 28705793
    Reference Link
  • 1.
    Goyal R, Vega M, Pastino A, Singh S, Guvendiren M, Kohn J, Murthy S, Schwarzbauer J. Development of hybrid scaffolds with natural extracellular matrix deposited within synthetic polymeric fibers. J Biomed Mater Res A. 2017;105(8):2162–2170. PMCID: PMC5493328
    Reference Link
  • 1.
    Celià-Terrassa T, Liu D, Choudhury A, Hang X, Wei Y, Zamalloa J, Alfaro-Aco R, Chakrabarti R, Jiang Y-Z, Koh B, Smith H, DeCoste C, Li J-J, Shao Z-M, Kang Y. Normal and cancerous mammary stem cells evade interferon-induced constraint through the miR-199a-LCOR axis. Nat Cell Biol. 2017;19(6):711–723. PMCID: PMC5481166
    Reference Link
  • 1.
    Siedlik M, Manivannan S, Kevrekidis I, Nelson C. Cell Division Induces and Switches Coherent Angular Motion within Bounded Cellular Collectives. Biophys J. 2017;112(11):2419–2427. PMCID: PMC5474845
    Reference Link
  • 1.
    Goodwin K, Nelson C. Generating tissue topology through remodeling of cell-cell adhesions. Exp Cell Res. 2017;358(1):45–51. PMCID: PMC5544595
    Reference Link
  • 1.
    Deshpande G, Barr J, Gerlitz O, Lebedeva L, Shidlovskii Y ii, Schedl P. Cells on the move: Modulation of guidance cues during germ cell migration. Fly (Austin). 2017;11(3):200–207. PMCID: PMC5552272
    Reference Link
  • 1.
    Anllo L, Schüpbach T. Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila. Dev Biol. 2016;414(2):193–206. PMCID: PMC4887387
    Reference Link
  • 1.
    Deshpande G, Manry D, Jourjine N, Mogila V, Mozes H, Bialistoky T, Gerlitz O, Schedl P. Role of the ABC transporter Mdr49 in Hedgehog signaling and germ cell migration. Development. 2016;143(12):2111–20. PMCID: PMC4920174
    Reference Link
  • 1.
    Alesi G, Jin L, Li D, Magliocca K, Kang Y, Chen Z, Shin D, Khuri F, Kang S. RSK2 signals through stathmin to promote microtubule dynamics and tumor metastasis. Oncogene. 2016;35(41):5412–5421. PMCID: PMC5226067
    Reference Link
  • 1.
    Nelson C. From static to animated: Measuring mechanical forces in tissues. J Cell Biol. 2017;216(1):29–30. PMCID: PMC5223620
    Reference Link
  • 1.
    Nerger B, Siedlik M, Nelson C. Microfabricated tissues for investigating traction forces involved in cell migration and tissue morphogenesis. Cell Mol Life Sci. 2017;74(10):1819–1834. PMCID: PMC5391279
    Reference Link
  • 1.
    Pang M-F, Georgoudaki A-M, Lambut L, Johansson J, Tabor V, Hagikura K, Jin Y, Jansson M, Alexander J, Nelson C, Jakobsson L, Betsholtz C, Sund M, Karlsson M, Fuxe J. TGF-β1-induced EMT promotes targeted migration of breast cancer cells through the lymphatic system by the activation of CCR7/CCL21-mediated chemotaxis. Oncogene. 2016;35(6):748–60. PMCID: PMC4753256
    Reference Link
  • 1.
    Gjorevski N, Piotrowski A, Varner V, Nelson C. Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep. 2015;5:11458. PMCID: PMC4499882
    Reference Link
  • 1.
    Piotrowski-Daspit A, Tien J, Nelson C. Interstitial fluid pressure regulates collective invasion in engineered human breast tumors via Snail, vimentin, and E-cadherin. Integr Biol (Camb). 2016;8(3):319–31. PMCID: PMC4792648
    Reference Link
  • 1.
    Nelson C. Collective migration in tissues. Mol Biol Cell. 2016;27(6):877. PMCID: PMC4791128
    Reference Link
  • 1.
    Desai V, Hsia H, Schwarzbauer J. Reversible modulation of myofibroblast differentiation in adipose-derived mesenchymal stem cells. PLoS One. 2014;9(1):e86865. PMCID: PMC3900664
    Reference Link
  • 1.
    Wong M-C, Kennedy W, Schwarzbauer J. Transcriptionally regulated cell adhesion network dictates distal tip cell directionality. Dev Dyn. 2014;243(8):999–1010. PMCID: PMC4321954
    Reference Link
  • 1.
    Fernández J, Rouzard K, Voronkov M, Huber K, Webb C, Stock J, Stock M, Gordon J, Pérez E. In vitro and clinical evaluation of SIG1273: a cosmetic functional ingredient with a broad spectrum of anti-aging and antioxidant activities. J Cosmet Dermatol. 2016;15(2):150–7. PMID: 26754448
    Reference Link
  • 1.
    Jaffe K, Grimes D, Schottenfeld-Roames J, Werner M, Ku T-S, Kim S, Pelliccia J, Morante N, Mitchell B, Burdine R. c21orf59/kurly Controls Both Cilia Motility and Polarization. Cell Rep. 2016;14(8):1841–9. PMCID: PMC4775428
    Reference Link

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