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Carbon

  • 1.
    Kayrouz C, Huang J, Hauser N, Seyedsayamdost M. Biosynthesis of selenium-containing small molecules in diverse microorganisms. Nature. 2022;610(7930):199–204. PMCID: 2881734
    Reference Link
  • 1.
    Bushin L, Covington B, Clark K, Caruso A, Seyedsayamdost M. Bicyclostreptins are radical SAM enzyme-modified peptides with unique cyclization motifs. Nat Chem Biol. 2022;18(10):1135–1143. PMCID: 6686864
    Reference Link
  • 1.
    Li A, Ducker G, Li Y, Seoane J, Xiao Y, Melemenidis S, Zhou Y, Liu L, Vanharanta S, Graves E, Rankin E, Curtis C, Massagué J, Rabinowitz J, Thompson C, Ye J. Metabolic Profiling Reveals a Dependency of Human Metastatic Breast Cancer on Mitochondrial Serine and One-Carbon Unit Metabolism. Mol Cancer Res. 2020;18(4):599–611. PMCID: PMC7127984
    Reference Link
  • 1.
    Itakura A, Chan K, Atkinson N, Pallesen L, Wang L, Reeves G, Patena W, Caspari O, Roth R, Goodenough U, McCormick A, Griffiths H, Jonikas M. A Rubisco-binding protein is required for normal pyrenoid number and starch sheath morphology in . Proc Natl Acad Sci U S A. 2019;116(37):18445–18454. PMCID: PMC6744930
    Reference Link
  • 1.
    Dekhne A, Shah K, Ducker G, Katinas J, Wong-Roushar J, Nayeen M, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O’Connor C, Dzinic S, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz J, Li J, Hou Z, Dann C, Gangjee A, Matherly L. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019;18(10):1787–1799. PMCID: PMC6774887
    Reference Link
  • 1.
    Ron-Harel N, Notarangelo G, Ghergurovich J, Paulo J, Sage P, Santos D, Satterstrom K, Gygi S, Rabinowitz J, Sharpe A, Haigis M. Defective respiration and one-carbon metabolism contribute to impaired naïve T cell activation in aged mice. Proc Natl Acad Sci U S A. 2018;115(52):13347–13352. PMCID: PMC6310842
    Reference Link
  • 1.
    Li S, Li Z, Park J, King C, Rabinowitz J, Wingreen N, Gitai Z. Escherichia coli translation strategies differ across carbon, nitrogen and phosphorus limitation conditions. Nat Microbiol. 2018;3(8):939–947. PMCID: PMC6278830
    Reference Link
  • 1.
    McKee S, Zhang S, Chen L, Rabinowitz J, Reyes T. Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. J Neurochem. 2018;145(5):362–373. PMCID: PMC6288810
    Reference Link
  • 1.
    Hui S, Ghergurovich J, Morscher R, Jang C, Teng X, Lu W, Esparza L, Reya T, Guo J, White E, Rabinowitz J. Glucose feeds the TCA cycle via circulating lactate. Nature. 2017;551(7678):115–118. PMCID: PMC5898814
    Reference Link
  • 1.
    Mitchell A, Wang W, Silhavy T. Novel RpoS-Dependent Mechanisms Strengthen the Envelope Permeability Barrier during Stationary Phase. J Bacteriol. 2017;199(2). PMCID: PMC5198486
    Reference Link
  • 1.
    Bren A, Park J, Towbin B, Dekel E, Rabinowitz J, Alon U. Glucose becomes one of the worst carbon sources for E.coli on poor nitrogen sources due to suboptimal levels of cAMP. Sci Rep. 2016;6:24834. PMCID: PMC4843011
    Reference Link
  • 1.
    Ron-Harel N, Santos D, Ghergurovich J, Sage P, Reddy A, Lovitch S, Dephoure N, Satterstrom K, Sheffer M, Spinelli J, Gygi S, Rabinowitz J, Sharpe A, Haigis M. Mitochondrial Biogenesis and Proteome Remodeling Promote One-Carbon Metabolism for T Cell Activation. Cell Metab. 2016;24(1):104–17. PMCID: PMC5330619
    Reference Link
  • 1.
    Ducker G, Chen L, Morscher R, Ghergurovich J, Esposito M, Teng X, Kang Y, Rabinowitz J. Reversal of Cytosolic One-Carbon Flux Compensates for Loss of the Mitochondrial Folate Pathway. Cell Metab. 2016;23(6):1140–1153. PMCID: PMC4909566
    Reference Link
  • 1.
    Gowers G-O, Robinson J, Brynildsen M. Starved Escherichia coli preserve reducing power under nitric oxide stress. Biochem Biophys Res Commun. 2016;476(1):29–34. PMID: 27207837
    Reference Link
  • 1.
    Ducker G, Rabinowitz J. One-Carbon Metabolism in Health and Disease. Cell Metab. 2017;25(1):27–42. PMCID: PMC5353360
    Reference Link
  • 1.
    Liu L, Shah S, Fan J, Park J, Wellen K, Rabinowitz J. Malic enzyme tracers reveal hypoxia-induced switch in adipocyte NADPH pathway usage. Nat Chem Biol. 2016;12(5):345–52. PMCID: PMC4891982
    Reference Link

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