1.Cota V, Sohrabi S, Kaletsky R, Murphy C. Oocyte mitophagy is critical for extended reproductive longevity. PLoS Genet. 2022;18(9):e1010400. PMCID: PMC9524673 Reference Link
1.McEnany J, Meir Y, Wingreen N. piRNAs of Caenorhabditis elegans broadly silence nonself sequences through functionally random targeting. Nucleic Acids Res. 2022;50(3):1416–1429. PMCID: PMC8860604 Reference Link
1.Rahimi M, Sohrabi S, Murphy C. Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant. Biophys J. 2022;121(4):515–524. PMCID: PMC8874029 Reference Link
1.Sohrabi S, Mor D, Kaletsky R, Keyes W, Murphy C. High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates. Commun Biol. 2021;4(1):203. PMCID: PMC7884385 Reference Link
1.Baumeister R, Murphy C, Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?. Cell Death Differ. 2021;28(4):1434–1436. PMCID: PMC8026991 Reference Link
1.Moore R, Kaletsky R, Murphy C. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021;2(1):100384. PMCID: PMC7960678 Reference Link
1.Lee Y, Jung Y, Jeong D-E, Hwang W, Ham S, Park H-E, Kwon S, Ashraf J, Murphy C, Lee S-J. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021;220(5). PMCID: PMC7941181 Reference Link
1.Chen Y-C, Seyedsayamdost M, Ringstad N. A microbial metabolite synergizes with endogenous serotonin to trigger reproductive behavior. Proc Natl Acad Sci U S A. 2020;117(48):30589–30598. PMCID: PMC7720207 Reference Link
1.Heimbucher T, Hog J, Gupta P, Murphy C. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020;11(1):4627. PMCID: PMC7532158 Reference Link
1.Mor D, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller G, Murphy C. Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020;117(42):26438–26447. PMCID: PMC7585014 Reference Link
1.Kaletsky R, Moore R, Vrla G, Parsons L, Gitai Z, Murphy C. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature. 2020;586(7829):445–451. PMCID: PMC8547118 Reference Link
1.Templeman N, Cota V, Keyes W, Kaletsky R, Murphy C. CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. Dev Cell. 2020;54(1):92–105.e5. PMCID: PMC7837322 Reference Link
1.Kaletsky R, Murphy C. Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age. Methods Mol Biol. 2020;2144:177–186. PMID: 32410035 Reference Link
1.Taylor N, Wei M-T, Stone H, Brangwynne C. Quantifying Dynamics in Phase-Separated Condensates Using Fluorescence Recovery after Photobleaching. Biophys J. 2019;117(7):1285–1300. PMCID: PMC6818185 Reference Link
1.Shi C, Booth L, Murphy C. Insulin-like peptides and the mTOR-TFEB pathway protect hermaphrodites from mating-induced death. Elife. 2019;8. PMCID: PMC6697448 Reference Link
1.Moore R, Kaletsky R, Murphy C. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 2019;177(7):1827–1841.e12. PMCID: PMC7518193 Reference Link
1.Heimbucher T, Murphy C. A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. Dev Cell. 2019;49(2):157–158. PMCID: PMC7452753 Reference Link
1.Liu M, Sharma A, Shaevitz J, Leifer A. Temporal processing and context dependency in response to mechanosensation. Elife. 2018;7. PMCID: PMC6054533 Reference Link
1.Kaletsky R, Yao V, Williams A, Runnels A, Tadych A, Zhou S, Troyanskaya O, Murphy C. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 2018;14(8):e1007559. PMCID: PMC6105014 Reference Link
1.Templeman N, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy C. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 2018;28(5):753–760.e4. PMCID: PMC5893159 Reference Link
1.Qi S, Pang Y, Hu Q, Liu Q, Li H, Zhou Y, He T, Liang Q, Liu Y, Yuan X, Luo G, Li H, Wang J, Yan N, Shi Y. Crystal structure of the Caenorhabditis elegans apoptosome reveals an octameric assembly of CED-4. Cell. 2010;141(3):446–57. PMID: 20434985 Reference Link
1.Son H, Seo M, Ham S, Hwang W, Lee D, An S, Artan M, Seo K, Kaletsky R, Arey R, Ryu Y, Ha C, Kim Y, Murphy C, Roh T-Y, Nam H, Lee S-J. RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nat Commun. 2017;8:14749. PMCID: PMC5347137 Reference Link
1.Hahm J-H, Kim S, DiLoreto R, Shi C, Lee S-J, Murphy C, Nam H. C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nat Commun. 2015;6:8919. PMCID: PMC4656132 Reference Link
1.Elbaum-Garfinkle S, Brangwynne C. Liquids, Fibers, and Gels: The Many Phases of Neurodegeneration. Dev Cell. 2015;35(5):531–532. PMID: 26651288 Reference Link
1.Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy C. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 2016;529(7584):92–6. PMCID: PMC4708089 Reference Link
1.Li L-B, Lei H, Arey R, Li P, Liu J, Murphy C, Xu X, Shen K. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 2016;26(5):605–15. PMCID: PMC4783184 Reference Link
1.Wong M-C, Kennedy W, Schwarzbauer J. Transcriptionally regulated cell adhesion network dictates distal tip cell directionality. Dev Dyn. 2014;243(8):999–1010. PMCID: PMC4321954 Reference Link