1.Kayrouz C, Huang J, Hauser N, Seyedsayamdost M. Biosynthesis of selenium-containing small molecules in diverse microorganisms. Nature. 2022;610(7930):199–204. PMCID: 2881734 Reference Link
1.Zhang Y, Cortez J, Hammer S, Carrasco-López C, Echauri S, Wiggins J, Wang W, Avalos J. Biosensor for branched-chain amino acid metabolism in yeast and applications in isobutanol and isopentanol production. Nat Commun. 2022;13(1):270. PMCID: PMC8755756 Reference Link
1.Howe R, Kelly M, Jimah J, Hodge D, Odom A. Isoprenoid biosynthesis inhibition disrupts Rab5 localization and food vacuolar integrity in Plasmodium falciparum. Eukaryot Cell. 2013;12(2):215–23. PMCID: PMC3571303 Reference Link
1.Lalwani M, Kawabe H, Mays R, Hoffman S, Avalos J. Optogenetic Control of Microbial Consortia Populations for Chemical Production. ACS Synth Biol. 2021;10(8):2015–2029. PMID: 34351122 Reference Link
1.López J, Duran L, Avalos J. Physiological limitations and opportunities in microbial metabolic engineering. Nat Rev Microbiol. 2022;20(1):35–48. PMCID: 5812522 Reference Link
1.Schild T, McReynolds M, Shea C, Low V, Schaffer B, Asara J, Piskounova E, Dephoure N, Rabinowitz J, Gomes A, Blenis J. NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma. Cell Rep. 2021;35(11):109238. PMID: 34133937 Reference Link
1.Li A, Okada B, Rosen P, Seyedsayamdost M. Piperacillin triggers virulence factor biosynthesis via the oxidative stress response in . Proc Natl Acad Sci U S A. 2021;118(26). PMCID: PMC8256049 Reference Link
1.Covington B, Xu F, Seyedsayamdost M. A Natural Product Chemist’s Guide to Unlocking Silent Biosynthetic Gene Clusters. Annu Rev Biochem. 2021;90:763–788. PMCID: PMC9148385 Reference Link
1.Klaus J, Coulon P, Koirala P, Seyedsayamdost M, Déziel E, Chandler J. Secondary metabolites from the Burkholderia pseudomallei complex: structure, ecology, and evolution. J Ind Microbiol Biotechnol. 2020;47(9-10):877–887. PMCID: PMC7746414 Reference Link
1.Li A, Mao D, Yoshimura A, Rosen P, Martin L, Gallant Étienne, Wühr M, Seyedsayamdost M. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020;11(1). PMCID: PMC7042699 Reference Link
1.Dekhne A, Shah K, Ducker G, Katinas J, Wong-Roushar J, Nayeen M, Doshi A, Ning C, Bao X, Frühauf J, Liu J, Wallace-Povirk A, O’Connor C, Dzinic S, White K, Kushner J, Kim S, Hüttemann M, Polin L, Rabinowitz J, Li J, Hou Z, Dann C, Gangjee A, Matherly L. Novel Pyrrolo[3,2-]pyrimidine Compounds Target Mitochondrial and Cytosolic One-carbon Metabolism with Broad-spectrum Antitumor Efficacy. Mol Cancer Ther. 2019;18(10):1787–1799. PMCID: PMC6774887 Reference Link
1.Clark K, Bushin L, Seyedsayamdost M. Aliphatic Ether Bond Formation Expands the Scope of Radical SAM Enzymes in Natural Product Biosynthesis. J Am Chem Soc. 2019;141(27):10610–10615. PMID: 31246011 Reference Link
1.Brown A, Chua N, Yan N. The shape of human squalene epoxidase expands the arsenal against cancer. Nat Commun. 2019;10(1):888. PMCID: PMC6384927 Reference Link
1.Xu F, Wu Y, Zhang C, Davis K, Moon K, Bushin L, Seyedsayamdost M. A genetics-free method for high-throughput discovery of cryptic microbial metabolites. Nat Chem Biol. 2019;15(2):161–168. PMCID: PMC6339573 Reference Link
1.Seyedsayamdost M. Toward a global picture of bacterial secondary metabolism. J Ind Microbiol Biotechnol. 2019;46(3-4):301–311. PMCID: PMC6779422 Reference Link
1.Mao D, Okada B, Wu Y, Xu F, Seyedsayamdost M. Recent advances in activating silent biosynthetic gene clusters in bacteria. Curr Opin Microbiol. 2018;45:156–163. PMCID: PMC6281788 Reference Link
1.Wu Y, Seyedsayamdost M. The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry. 2018;57(29):4247–4251. PMID: 29975047 Reference Link
1.Okada B, Seyedsayamdost M. Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules. FEMS Microbiol Rev. 2017;41(1):19–33. PMCID: PMC5233716 Reference Link
1.Wang R, Gallant Étienne, Seyedsayamdost M. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens. mBio. 2016;7(2):e02118. PMCID: PMC4807370 Reference Link
1.Baars O, Zhang X, Morel F, Seyedsayamdost M. The Siderophore Metabolome of Azotobacter vinelandii. Appl Environ Microbiol. 2016;82(1):27–39. PMCID: PMC4702634 Reference Link
1.Seyedsayamdost M. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proc Natl Acad Sci U S A. 2014;111(20):7266–71. PMCID: PMC4034229 Reference Link
1.Forneris C, Ozturk S, Gibson M, Sorensen E, Seyedsayamdost M. In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. ACS Chem Biol. 2017;12(9):2248–2253. PMCID: PMC5617736 Reference Link
1.Seyedsayamdost M, Case R, Kolter R, Clardy J. The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. Nat Chem. 2011;3(4):331–5. PMCID: PMC3376411 Reference Link
1.Donia M, Cimermancic P, Schulze C, Brown L, Martin J, Mitreva M, Clardy J, Linington R, Fischbach M. A systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics. Cell. 2014;158(6):1402–1414. PMCID: PMC4164201 Reference Link
