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Biofilms

  • 1.
    Prentice J, Bridges A, Bassler B. Synergy between c-di-GMP and Quorum-Sensing Signaling in Vibrio cholerae Biofilm Morphogenesis. J Bacteriol. 2022;204(10):e0024922. PMCID: PMC9578409
    Reference Link
  • 1.
    Taylor I, Jeffrey P, Moustafa D, Goldberg J, Bassler B. The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against . Biochemistry. 2022;61(17):1894–1903. PMCID: PMC9454246
    Reference Link
  • 1.
    Bridges A, Prentice J, Wingreen N, Bassler B. Signal Transduction Network Principles Underlying Bacterial Collective Behaviors. Annu Rev Microbiol. 2022;76:235–257. PMCID: PMC9463083
    Reference Link
  • 1.
    Bridges A, Prentice J, Fei C, Wingreen N, Bassler B. Quantitative input-output dynamics of a c-di-GMP signal transduction cascade in Vibrio cholerae. PLoS Biol. 2022;20(3):e3001585. PMCID: PMC8967002
    Reference Link
  • 1.
    Jemielita M, Mashruwala A, Valastyan J, Wingreen N, Bassler B. Secreted Proteases Control the Timing of Aggregative Community Formation in Vibrio cholerae. mBio. 2021;12(6):e0151821. PMCID: PMC8609355
    Reference Link
  • 1.
    Qin B, Fei C, Wang B, Stone H, Wingreen N, Bassler B. Hierarchical transitions and fractal wrinkling drive bacterial pellicle morphogenesis. Proc Natl Acad Sci U S A. 2021;118(20). PMCID: PMC8157956
    Reference Link
  • 1.
    Narla A, Borenstein D, Wingreen N. A biophysical limit for quorum sensing in biofilms. Proc Natl Acad Sci U S A. 2021;118(21). PMCID: PMC8166027
    Reference Link
  • 1.
    Bridges A, Bassler B. Inverse regulation of biofilm dispersal by polyamine signals. Elife. 2021;10. PMCID: PMC8079147
    Reference Link
  • 1.
    Wong G, Antani J, Lele P, Chen J, Nan B, Kühn M, Persat A, Bru J-L, Høyland-Kroghsbo N, Siryaporn A, Conrad J, Carrara F, Yawata Y, Stocker R, Brun Y, Whitfield G, Lee C, de Anda J, Schmidt W, Golestanian R, O’Toole G, Floyd K, Yildiz F, Yang S, Jin F, Toyofuku M, Eberl L, Nomura N, Zacharoff L, El-Naggar M, Yalcin S, Malvankar N, Rojas-Andrade M, Hochbaum A, Yan J, Stone H, Wingreen N, Bassler B, Wu Y, Xu H, Drescher K, Dunkel J. Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation. Phys Biol. 2021;18(5). PMCID: PMC8506656
    Reference Link
  • 1.
    Scheffler R, Sugimoto Y, Bratton B, Ellison C, Koch M, Donia M, Gitai Z. Pseudomonas aeruginosa detachment from surfaces via a self-made small molecule. J Biol Chem. 2021;296:100279. PMCID: PMC7949062
    Reference Link
  • 1.
    Bridges A, Fei C, Bassler B. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020;117(51):32639–32647. PMCID: PMC7768729
    Reference Link
  • 1.
    Mashruwala A, Bassler B. The Vibrio cholerae Quorum-Sensing Protein VqmA Integrates Cell Density, Environmental, and Host-Derived Cues into the Control of Virulence. mBio. 2020;11(4). PMCID: PMC7387800
    Reference Link
  • 1.
    Mukherjee S, Jemielita M, Stergioula V, Tikhonov M, Bassler B. Photosensing and quorum sensing are integrated to control Pseudomonas aeruginosa collective behaviors. PLoS Biol. 2019;17(12):e3000579. PMCID: PMC6932827
    Reference Link
  • 1.
    Qin B, Fei C, Bridges A, Mashruwala A, Stone H, Wingreen N, Bassler B. Cell position fates and collective fountain flow in bacterial biofilms revealed by light-sheet microscopy. Science. 2020;369(6499):71–77. PMCID: PMC7426073
    Reference Link
  • 1.
    Fei C, Mao S, Yan J, Alert R, Stone H, Bassler B, Wingreen N, Košmrlj A. Nonuniform growth and surface friction determine bacterial biofilm morphology on soft substrates. Proc Natl Acad Sci U S A. 2020;117(14):7622–7632. PMCID: PMC7148565
    Reference Link
  • 1.
    Bridges A, Bassler B. The intragenus and interspecies quorum-sensing autoinducers exert distinct control over Vibrio cholerae biofilm formation and dispersal. PLoS Biol. 2019;17(11):e3000429. PMCID: PMC6872173
    Reference Link
  • 1.
    Silpe J, Bassler B. A Host-Produced Quorum-Sensing Autoinducer Controls a Phage Lysis-Lysogeny Decision. Cell. 2019;176(1-2):268–280.e13. PMCID: PMC6329655
    Reference Link
  • 1.
    Yan J, Bassler B. Surviving as a Community: Antibiotic Tolerance and Persistence in Bacterial Biofilms. Cell Host Microbe. 2019;26(1):15–21. PMCID: PMC6629468
    Reference Link
  • 1.
    Sanfilippo J, Lorestani A, Koch M, Bratton B, Siryaporn A, Stone H, Gitai Z. Microfluidic-based transcriptomics reveal force-independent bacterial rheosensing. Nat Microbiol. 2019;4(8):1274–1281. PMCID: PMC6656604
    Reference Link
  • 1.
    Mukherjee S, Bassler B. Bacterial quorum sensing in complex and dynamically changing environments. Nat Rev Microbiol. 2019;17(6):371–382. PMCID: PMC6615036
    Reference Link
  • 1.
    Yan J, Fei C, Mao S, Moreau A, Wingreen N, Košmrlj A, Stone H, Bassler B. Mechanical instability and interfacial energy drive biofilm morphogenesis. Elife. 2019;8. PMCID: PMC6453567
    Reference Link
  • 1.
    Yan J, Moreau A, Khodaparast S, Perazzo A, Feng J, Fei C, Mao S, Mukherjee S, Košmrlj A, Wingreen N, Bassler B, Stone H. Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. Adv Mater. 2018;30(46):e1804153. PMCID: PMC8865467
    Reference Link
  • 1.
    Mukherjee S, Moustafa D, Stergioula V, Smith C, Goldberg J, Bassler B. The PqsE and RhlR proteins are an autoinducer synthase-receptor pair that control virulence and biofilm development in . Proc Natl Acad Sci U S A. 2018;115(40):E9411-E9418. PMCID: PMC6176596
    Reference Link
  • 1.
    Kannan A, Yang Z, Kim M, Stone H, Siryaporn A. Dynamic switching enables efficient bacterial colonization in flow. Proc Natl Acad Sci U S A. 2018;115(21):5438–5443. PMCID: PMC6003447
    Reference Link
  • 1.
    Mao D, Bushin L, Moon K, Wu Y, Seyedsayamdost M. Discovery of as a global regulator of secondary metabolism and virulence in E264. Proc Natl Acad Sci U S A. 2017;114(14):E2920-E2928. PMCID: PMC5389298
    Reference Link
  • 1.
    Yan J, Nadell C, Stone H, Wingreen N, Bassler B. Extracellular-matrix-mediated osmotic pressure drives Vibrio cholerae biofilm expansion and cheater exclusion. Nat Commun. 2017;8(1):327. PMCID: PMC5569112
    Reference Link
  • 1.
    Mukherjee S, Moustafa D, Smith C, Goldberg J, Bassler B. The RhlR quorum-sensing receptor controls Pseudomonas aeruginosa pathogenesis and biofilm development independently of its canonical homoserine lactone autoinducer. PLoS Pathog. 2017;13(7):e1006504. PMCID: PMC5531660
    Reference Link
  • 1.
    Sabass B, Koch M, Liu G, Stone H, Shaevitz J. Force generation by groups of migrating bacteria. Proc Natl Acad Sci U S A. 2017;114(28):7266–7271. PMCID: PMC5514709
    Reference Link
  • 1.
    Kim M, Zhao A, Wang A, Brown Z, Muir T, Stone H, Bassler B. Surface-attached molecules control Staphylococcus aureus quorum sensing and biofilm development. Nat Microbiol. 2017;2:17080. PMCID: PMC5526357
    Reference Link
  • 1.
    Yan J, Nadell C, Bassler B. Environmental fluctuation governs selection for plasticity in biofilm production. ISME J. 2017;11(7):1569–1577. PMCID: PMC5520152
    Reference Link
  • 1.
    Papenfort K, Silpe J, Schramma K, Cong J-P, Seyedsayamdost M, Bassler B. A Vibrio cholerae autoinducer-receptor pair that controls biofilm formation. Nat Chem Biol. 2017;13(5):551–557. PMCID: PMC5391282
    Reference Link
  • 1.
    Paczkowski J, Mukherjee S, McCready A, Cong J-P, Aquino C, Kim H, Henke B, Smith C, Bassler B. Flavonoids Suppress Virulence through Allosteric Inhibition of Quorum-sensing Receptors. J Biol Chem. 2017;292(10):4064–4076. PMCID: PMC5354481
    Reference Link
  • 1.
    Nadell C, Ricaurte D, Yan J, Drescher K, Bassler B. Flow environment and matrix structure interact to determine spatial competition in biofilms. Elife. 2017;6. PMCID: PMC5283829
    Reference Link
  • 1.
    Kim M, Ingremeau F, Zhao A, Bassler B, Stone H. Local and global consequences of flow on bacterial quorum sensing. Nat Microbiol. 2016;1:15005. PMCID: PMC5010089
    Reference Link
  • 1.
    Yan J, Sharo A, Stone H, Wingreen N, Bassler B. Vibrio cholerae biofilm growth program and architecture revealed by single-cell live imaging. Proc Natl Acad Sci U S A. 2016;113(36):E5337–43. PMCID: PMC5018804
    Reference Link
  • 1.
    Orman M, Brynildsen M. Persister formation in Escherichia coli can be inhibited by treatment with nitric oxide. Free Radic Biol Med. 2016;93:145–54. PMCID: PMC4898466
    Reference Link
  • 1.
    Henry T, Brynildsen M. Quantifying Current Events Identifies a Novel Endurance Regulator. Trends Microbiol. 2016;24(5):324–326. PMCID: PMC4841710
    Reference Link
  • 1.
    Federle M, Bassler B. Interspecies communication in bacteria. J Clin Invest. 2003;112(9):1291–9. PMCID: PMC228483
    Reference Link
  • 1.
    Hammer B, Bassler B. Quorum sensing controls biofilm formation in Vibrio cholerae. Mol Microbiol. 2003;50(1):101–4. PMID: 14507367
    Reference Link
  • 1.
    Camilli A, Bassler B. Bacterial small-molecule signaling pathways. Science. 2006;311(5764):1113–6. PMCID: PMC2776824
    Reference Link
  • 1.
    Waters C, Lu W, Rabinowitz J, Bassler B. Quorum sensing controls biofilm formation in Vibrio cholerae through modulation of cyclic di-GMP levels and repression of vpsT. J Bacteriol. 2008;190(7):2527–36. PMCID: PMC2293178
    Reference Link
  • 1.
    Nadell C, Bassler B, Levin S. Observing bacteria through the lens of social evolution. J Biol. 2008;7(7):27. PMCID: PMC2776406
    Reference Link
  • 1.
    Hammer B, Bassler B. Distinct sensory pathways in Vibrio cholerae El Tor and classical biotypes modulate cyclic dimeric GMP levels to control biofilm formation. J Bacteriol. 2009;191(1):169–77. PMCID: PMC2612459
    Reference Link
  • 1.
    Chen G, Swem L, Swem D, Stauff D, O’Loughlin C, Jeffrey P, Bassler B, Hughson F. A strategy for antagonizing quorum sensing. Mol Cell. 2011;42(2):199–209. PMCID: PMC3092643
    Reference Link
  • 1.
    Ng W-L, Perez L, Cong J, Semmelhack M, Bassler B. Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios. PLoS Pathog. 2012;8(6):e1002767. PMCID: PMC3386246
    Reference Link
  • 1.
    Nadell C, Bucci V, Drescher K, Levin S, Bassler B, Xavier J. Cutting through the complexity of cell collectives. Proc Biol Sci. 2013;280(1755):20122770. PMCID: PMC3574390
    Reference Link
  • 1.
    Drescher K, Shen Y, Bassler B, Stone H. Biofilm streamers cause catastrophic disruption of flow with consequences for environmental and medical systems. Proc Natl Acad Sci U S A. 2013;110(11):4345–50. PMCID: PMC3600445
    Reference Link
  • 1.
    O’Loughlin C, Miller L, Siryaporn A, Drescher K, Semmelhack M, Bassler B. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc Natl Acad Sci U S A. 2013;110(44):17981–6. PMCID: PMC3816427
    Reference Link
  • 1.
    Drescher K, Nadell C, Stone H, Wingreen N, Bassler B. Solutions to the public goods dilemma in bacterial biofilms. Curr Biol. 2014;24(1):50–55. PMCID: PMC3935403
    Reference Link
  • 1.
    Schluter J, Nadell C, Bassler B, Foster K. Adhesion as a weapon in microbial competition. ISME J. 2015;9(1):139–49. PMCID: PMC4268496
    Reference Link

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