1.Guest R, Silhavy T. Cracking outer membrane biogenesis. Biochim Biophys Acta Mol Cell Res. 2023;1870(2):119405. PMCID: PMC9878550 Reference Link
1.Sun J, Rutherford S, Silhavy T, Huang K. Physical properties of the bacterial outer membrane. Nat Rev Microbiol. 2022;20(4):236–248. PMCID: PMC8934262 Reference Link
1.Doyle M, Jimah J, Dowdy T, Ohlemacher S, Larion M, Hinshaw J, Bernstein H. Cryo-EM structures reveal multiple stages of bacterial outer membrane protein folding. Cell. 2022;185(7):1143–1156.e13. PMCID: PMC8985213 Reference Link
1.Benn G, Mikheyeva I, Inns P, Forster J, Ojkic N, Bortolini C, Ryadnov M, Kleanthous C, Silhavy T, Hoogenboom B. Phase separation in the outer membrane of . Proc Natl Acad Sci U S A. 2021;118(44). PMCID: PMC8612244 Reference Link
1.Combs A, Silhavy T. The sacrificial adaptor protein Skp functions to remove stalled substrates from the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2022;119(1). PMCID: PMC8740687 Reference Link
1.Guest R, Rutherford S, Silhavy T. Border Control: Regulating LPS Biogenesis. Trends Microbiol. 2021;29(4):334–345. PMCID: PMC7969359 Reference Link
1.Hart E, Silhavy T. Functions of the BamBCDE Lipoproteins Revealed by Bypass Mutations in BamA. J Bacteriol. 2020;202(21). PMCID: PMC7549358 Reference Link
1.Hart E, Gupta M, Wühr M, Silhavy T. The gain-of-function allele bypasses the essential requirement for BamD in β-barrel outer membrane protein assembly. Proc Natl Acad Sci U S A. 2020;117(31):18737–18743. PMCID: PMC7414184 Reference Link
1.Taylor J, Bratton B, Sichel S, Blair K, Jacobs H, DeMeester K, Kuru E, Gray J, Biboy J, VanNieuwenhze M, Vollmer W, Grimes C, Shaevitz J, Salama N. Distinct cytoskeletal proteins define zones of enhanced cell wall synthesis in . Elife. 2020;9. PMCID: PMC7012605 Reference Link
1.Guest R, Guerra D, Wissler M, Grimm J, Silhavy T. YejM Modulates Activity of the YciM/FtsH Protease Complex To Prevent Lethal Accumulation of Lipopolysaccharide. mBio. 2020;11(2). PMCID: PMC7157816 Reference Link
1.Eickhoff M, Bassler B. Vibrio fischeri siderophore production drives competitive exclusion during dual-species growth. Mol Microbiol. 2020;114(2):244–261. PMCID: PMC7541421 Reference Link
1.Hart E, Mitchell A, Konovalova A, Grabowicz M, Sheng J, Han X, Rodriguez-Rivera F, Schwaid A, Malinverni J, Balibar C, Bodea S, Si Q, Wang H, Homsher M, Painter R, Ogawa A, Sutterlin H, Roemer T, Black T, Rothman D, Walker S, Silhavy T. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019;116(43):21748–21757. PMCID: PMC6815139 Reference Link
1.Hart E, Gupta M, Wühr M, Silhavy T. The Synthetic Phenotype of Δ Δ Double Mutants Results from a Lethal Jamming of the Bam Complex by the Lipoprotein RcsF. mBio. 2019;10(3). PMCID: PMC6529638 Reference Link
1.Ricci D, Silhavy T. Outer Membrane Protein Insertion by the β-barrel Assembly Machine. EcoSal Plus. 2019;8(2). PMCID: PMC6419762 Reference Link
1.Hart E, O’Connell A, Tang K, Wzorek J, Grabowicz M, Kahne D, Silhavy T. Fine-Tuning of σ Activation Suppresses Multiple Assembly-Defective Mutations in Escherichia coli. J Bacteriol. 2019;201(11). PMCID: PMC6509652 Reference Link
1.Mitchell A, Srikumar T, Silhavy T. Cyclic Enterobacterial Common Antigen Maintains the Outer Membrane Permeability Barrier of Escherichia coli in a Manner Controlled by YhdP. mBio. 2018;9(4). PMCID: PMC6083912 Reference Link
1.Konovalova A, Grabowicz M, Balibar C, Malinverni J, Painter R, Riley D, Mann P, Wang H, Garlisi C, Sherborne B, Rigel N, Ricci D, Black T, Roemer T, Silhavy T, Walker S. Inhibitor of intramembrane protease RseP blocks the σ response causing lethal accumulation of unfolded outer membrane proteins. Proc Natl Acad Sci U S A. 2018;115(28):E6614-E6621. PMCID: PMC6048503 Reference Link
1.May K, Silhavy T. The Phospholipase PldA Regulates Outer Membrane Homeostasis via Lipid Signaling. mBio. 2018;9(2). PMCID: PMC5874903 Reference Link
1.Lee J, Sutterlin H, Wzorek J, Mandler M, Hagan C, Grabowicz M, Tomasek D, May M, Hart E, Silhavy T, Kahne D. Substrate binding to BamD triggers a conformational change in BamA to control membrane insertion. Proc Natl Acad Sci U S A. 2018;115(10):2359–2364. PMCID: PMC5877925 Reference Link
1.Konovalova A, Kahne D, Silhavy T. Outer Membrane Biogenesis. Annu Rev Microbiol. 2017;71:539–556. PMCID: PMC5778897 Reference Link
1.McCabe A, Ricci D, Adetunji M, Silhavy T. Conformational Changes That Coordinate the Activity of BamA and BamD Allowing β-Barrel Assembly. J Bacteriol. 2017;199(20). PMCID: PMC5637172 Reference Link
1.Soltes G, Martin N, Park E, Sutterlin H, Silhavy T. Distinctive Roles for Periplasmic Proteases in the Maintenance of Essential Outer Membrane Protein Assembly. J Bacteriol. 2017;199(20). PMCID: PMC5637175 Reference Link
1.Sacco S, Adolfsen K, Brynildsen M. An integrated network analysis identifies how ArcAB enables metabolic oscillations in the nitric oxide detoxification network of Escherichia coli. Biotechnol J. 2017;12(8). PMID: 28449226 Reference Link
1.Grabowicz M, Silhavy T. Redefining the essential trafficking pathway for outer membrane lipoproteins. Proc Natl Acad Sci U S A. 2017;114(18):4769–4774. PMCID: PMC5422772 Reference Link
1.Okuda S, Sherman D, Silhavy T, Ruiz N, Kahne D. Lipopolysaccharide transport and assembly at the outer membrane: the PEZ model. Nat Rev Microbiol. 2016;14(6):337–45. PMCID: PMC4937791 Reference Link
1.Mahoney T, Ricci D, Silhavy T. Classifying β-Barrel Assembly Substrates by Manipulating Essential Bam Complex Members. J Bacteriol. 2016;198(14):1984–92. PMCID: PMC4936103 Reference Link
1.Konovalova A, Mitchell A, Silhavy T. A lipoprotein/β-barrel complex monitors lipopolysaccharide integrity transducing information across the outer membrane. Elife. 2016;5. PMCID: PMC4942254 Reference Link
1.Konovalova A, Schwalm J, Silhavy T. A Suppressor Mutation That Creates a Faster and More Robust σE Envelope Stress Response. J Bacteriol. 2016;198(17):2345–51. PMCID: PMC4984553 Reference Link
1.Konovalova A, Silhavy T. Outer membrane lipoprotein biogenesis: Lol is not the end. Philos Trans R Soc Lond B Biol Sci. 2015;370(1679). PMCID: PMC4632606 Reference Link
1.Grabowicz M, Yeh J, Silhavy T. Dominant negative lptE mutation that supports a role for LptE as a plug in the LptD barrel. J Bacteriol. 2013;195(6):1327–34. PMCID: PMC3591993 Reference Link
1.Lee J, Xue M, Wzorek J, Wu T, Grabowicz M, Gronenberg L, Sutterlin H, Davis R, Ruiz N, Silhavy T, Kahne D. Characterization of a stalled complex on the β-barrel assembly machine. Proc Natl Acad Sci U S A. 2016;113(31):8717–22. PMCID: PMC4978274 Reference Link
1.Soltes G, Schwalm J, Ricci D, Silhavy T. The Activity of Escherichia coli Chaperone SurA Is Regulated by Conformational Changes Involving a Parvulin Domain. J Bacteriol. 2016;198(6):921–9. PMCID: PMC4772605 Reference Link
1.Sutterlin H, Shi H, May K, Miguel A, Khare S, Huang K, Silhavy T. Disruption of lipid homeostasis in the Gram-negative cell envelope activates a novel cell death pathway. Proc Natl Acad Sci U S A. 2016;113(11):E1565–74. PMCID: PMC4801249 Reference Link