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Antiviral Agents

  • 1.
    Justice J, Cristea I. Nuclear antiviral innate responses at the intersection of DNA sensing and DNA repair. Trends Microbiol. 2022;30(11):1056–1071. PMCID: PMC9560981
    Reference Link
  • 1.
    Howard T, Lum K, Kennedy M, Cristea I. The Nuclear DNA Sensor IFI16 Indiscriminately Binds to and Diminishes Accessibility of the HSV-1 Genome to Suppress Infection. mSystems. 2022;7(3):e0019822. PMCID: PMC9239196
    Reference Link
  • 1.
    Pitre E, Velthuis A. Tinker, tailor, antiviral: RNA virus inhibition by induced recombination. Trends Biochem Sci. 2022;47(6):456–458. PMID: 35123872
    Reference Link
  • 1.
    Shekhtman L, Cotler S, Ploss A, Dahari H. Mathematical modeling suggests that entry-inhibitor bulevirtide may interfere with hepatitis D virus clearance from circulation. J Hepatol. 2022;76(5):1229–1231. PMCID: PMC9018506
    Reference Link
  • 1.
    Pitre E, Velthuis A. Understanding viral replication and transcription using single-molecule techniques. Enzymes. 2021;49:83–113. PMID: 34696840
    Reference Link
  • 1.
    Sheng X, Cristea I. The antiviral sirtuin 3 bridges protein acetylation to mitochondrial integrity and metabolism during human cytomegalovirus infection. PLoS Pathog. 2021;17(4):e1009506. PMCID: PMC8078788
    Reference Link
  • 1.
    Nimgaonkar I, Archer N, Becher I, Shahrad M, LeDesma R, Mateus A, Caballero-Gómez J, Berneshawi A, Ding Q, Douam F, Gaska J, Savitski M, Kim H, Ploss A. Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90. Antiviral Res. 2021;185:104997. PMCID: PMC8649941
    Reference Link
  • 1.
    Iserman C, Roden C, Boerneke M, Sealfon R, McLaughlin G, Jungreis I, Fritch E, Hou Y, Ekena J, Weidmann C, Theesfeld C, Kellis M, Troyanskaya O, Baric R, Sheahan T, Weeks K, Gladfelter A. Genomic RNA Elements Drive Phase Separation of the SARS-CoV-2 Nucleocapsid. Mol Cell. 2020;80(6):1078–1091.e6. PMCID: PMC7691212
    Reference Link
  • 1.
    Howard T, Cristea I. Interrogating Host Antiviral Environments Driven by Nuclear DNA Sensing: A Multiomic Perspective. Biomolecules. 2020;10(12). PMCID: PMC7761228
    Reference Link
  • 1.
    Ploss A, Kapoor A. Animal Models of Hepatitis C Virus Infection. Cold Spring Harb Perspect Med. 2020;10(5). PMCID: PMC7197424
    Reference Link
  • 1.
    Laval K, Van Cleemput J, Vernejoul J, Enquist L. Alphaherpesvirus infection of mice primes PNS neurons to an inflammatory state regulated by TLR2 and type I IFN signaling. PLoS Pathog. 2019;15(11):e1008087. PMCID: PMC6824567
    Reference Link
  • 1.
    Mesev E, LeDesma R, Ploss A. Decoding type I and III interferon signalling during viral infection. Nat Microbiol. 2019;4(6):914–924. PMCID: PMC6554024
    Reference Link
  • 1.
    Winer B, Huang T, Pludwinski E, Heller B, Wojcik F, Lipkowitz G, Parekh A, Cho C, Shrirao A, Muir T, Novik E, Ploss A. Long-term hepatitis B infection in a scalable hepatic co-culture system. Nat Commun. 2017;8(1):125. PMCID: PMC5527081
    Reference Link
  • 1.
    Shirvani-Dastgerdi E, Winer B, Celià-Terrassa T, Kang Y, Tabernero D, Yagmur E, Rodríguez-Frías F, Gregori J, Luedde T, Trautwein C, Ploss A, Tacke F. Selection of the highly replicative and partially multidrug resistant rtS78T HBV polymerase mutation during TDF-ETV combination therapy. J Hepatol. 2017;67(2):246–254. PMCID: PMC6016549
    Reference Link
  • 1.
    Winer B, Huang T, Low B, Avery C, Pais M-A, Hrebikova G, Siu E, Chiriboga L, Wiles M, Ploss A. Recapitulation of treatment response patterns in a novel humanized mouse model for chronic hepatitis B virus infection. Virology. 2017;502:63–72. PMCID: PMC5414730
    Reference Link

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