Tang J, Brynildsen M. Genome-wide mapping of fluoroquinolone-stabilized DNA gyrase cleavage sites displays drug specific effects that correlate with bacterial persistence. Nucleic Acids Res. 2023;51(3):1208–1228. PMCID: PMC9943676

Guest R, Silhavy T. Cracking outer membrane biogenesis. Biochim Biophys Acta Mol Cell Res. 2023;1870(2):119405. PMCID: PMC9878550

Carson D, Patiño M, Elashal H, Cartagena A, Zhang Y, Whitley M, So L, Kayser-Browne A, Earl A, Bhattacharyya R, Link J. Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against . ACS Infect Dis. 2023;9(1):111–121. PMCID: PMC10038104

Chiu S, Hancock A, Schofner B, Sniezek K, Soto-Echevarria N, Leon G, Sivaloganathan D, Wan X, Brynildsen M. Causes of polymyxin treatment failure and new derivatives to fill the gap. J Antibiot (Tokyo). 2022;75(11):593–609. PMCID: 2048009

Han E, Lee S, Hoshino S, Seyedsayamdost M. Targeted Discovery of Cryptic Metabolites with Antiproliferative Activity. ACS Chem Biol. 2022;17(11):3121–3130. PMID: 36228140

Taylor I, Murray-Nerger L, Greco T, Liu D, Cristea I, Bassler B. Protein Interaction Networks of Catalytically Active and Catalytically Inactive PqsE in Pseudomonas aeruginosa. mBio. 2022;13(5):e0155922. PMCID: PMC9600345

Taylor I, Jeffrey P, Moustafa D, Goldberg J, Bassler B. The PqsE Active Site as a Target for Small Molecule Antimicrobial Agents against . Biochemistry. 2022;61(17):1894–1903. PMCID: PMC9454246

Do T, Thokkadam A, Leach R, Link J. Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in . ACS Chem Biol. 2022;17(8):2332–2343. PMCID: PMC9454059

Lee S, Seyedsayamdost M. Induction of Diverse Cryptic Fungal Metabolites by Steroids and Channel Blockers. Angew Chem Int Ed Engl. 2022;61(29):e202204519. PMCID: PMC9276648

Simanek K, Taylor I, Richael E, Lasek-Nesselquist E, Bassler B, Paczkowski J. The PqsE-RhlR Interaction Regulates RhlR DNA Binding to Control Virulence Factor Production in . Microbiol Spectr. 2022;10(1):e0210821. PMCID: PMC8754118

Murawski A, Rittenbach K, DeCoste C, Laevsky G, Brynildsen M. Counting Chromosomes in Individual Bacteria to Quantify Their Impacts on Persistence. Methods Mol Biol. 2021;2357:125–146. PMCID: 7136161

Lemma A, Brynildsen M. Toxin Induction or Inhibition of Transcription or Translation Posttreatment Increases Persistence to Fluoroquinolones. mBio. 2021;12(4):e0198321. PMCID: PMC8406316

Rued B, Covington B, Bushin L, Szewczyk G, Laczkovich I, Seyedsayamdost M, Federle M. Quorum Sensing in Streptococcus mutans Regulates Production of Tryglysin, a Novel RaS-RiPP Antimicrobial Compound. mBio. 2021;12(2). PMCID: PMC8092268

Murawski A, Brynildsen M. Ploidy is an important determinant of fluoroquinolone persister survival. Curr Biol. 2021;31(10):2039–2050.e7. PMCID: PMC8183807

Bridges A, Fei C, Bassler B. Identification of signaling pathways, matrix-digestion enzymes, and motility components controlling biofilm dispersal. Proc Natl Acad Sci U S A. 2020;117(51):32639–32647. PMCID: PMC7768729

Claesen J, Spagnolo J, Ramos S, Kurita K, Byrd A, Aksenov A, Melnik A, Wong W, Wang S, Hernandez R, Donia M, Dorrestein P, Kong H, Segre J, Linington R, Fischbach M, Lemon K. A antibiotic modulates human skin microbiota composition in hair follicles. Sci Transl Med. 2020;12(570). PMCID: PMC8478231

Zhang C, Seyedsayamdost M. Discovery of a Cryptic Depsipeptide from Streptomyces ghanaensis via MALDI-MS-Guided High-Throughput Elicitor Screening. Angew Chem Int Ed Engl. 2020;59(51):23005–23009. PMID: 32790054

Martin J, Sheehan J, Bratton B, Moore G, Mateus A, Li S, Kim H, Rabinowitz J, Typas A, Savitski M, Wilson M, Gitai Z. A Dual-Mechanism Antibiotic Kills Gram-Negative Bacteria and Avoids Drug Resistance. Cell. 2020;181(7):1518–1532.e14. PMCID: PMC7780349

Li A, Mao D, Yoshimura A, Rosen P, Martin L, Gallant Étienne, Wühr M, Seyedsayamdost M. Multi-Omic Analyses Provide Links between Low-Dose Antibiotic Treatment and Induction of Secondary Metabolism in Burkholderia thailandensis. mBio. 2020;11(1). PMCID: PMC7042699

Park J-D, Moon K, Miller C, Rose J, Xu F, Ebmeier C, Jacobsen J, Mao D, Old W, DeShazer D, Seyedsayamdost M. Thailandenes, Cryptic Polyene Natural Products Isolated from Using Phenotype-Guided Transposon Mutagenesis. ACS Chem Biol. 2020;15(5):1195–1203. PMCID: PMC9106368

Cheung-Lee W, Parry M, Zong C, Cartagena A, Darst S, Connell N, Russo R, Link J. Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem. 2020;21(9):1335–1340. PMCID: PMC7205569

Hart E, Mitchell A, Konovalova A, Grabowicz M, Sheng J, Han X, Rodriguez-Rivera F, Schwaid A, Malinverni J, Balibar C, Bodea S, Si Q, Wang H, Homsher M, Painter R, Ogawa A, Sutterlin H, Roemer T, Black T, Rothman D, Walker S, Silhavy T. A small-molecule inhibitor of BamA impervious to efflux and the outer membrane permeability barrier. Proc Natl Acad Sci U S A. 2019;116(43):21748–21757. PMCID: PMC6815139

Ozturk S, Forneris C, Nguy A, Sorensen E, Seyedsayamdost M. Modulating OxyB-Catalyzed Cross-Coupling Reactions in Vancomycin Biosynthesis by Incorporation of Diverse d-Tyr Analogues. J Org Chem. 2018;83(13):7309–7317. PMID: 29806454

Yan J, Bassler B. Surviving as a Community: Antibiotic Tolerance and Persistence in Bacterial Biofilms. Cell Host Microbe. 2019;26(1):15–21. PMCID: PMC6629468

Liu M, El-Hossary E, Oelschlaeger T, Donia M, Quinn R, Abdelmohsen U. Potential of marine natural products against drug-resistant bacterial infections. Lancet Infect Dis. 2019;19(7):e237-e245. PMID: 31031171

Balaban N, Helaine S, Lewis K, Ackermann M, Aldridge B, Andersson D, Brynildsen M, Bumann D, Camilli A, Collins J, Dehio C, Fortune S, Ghigo J-M, Hardt W-D, Harms A, Heinemann M, Hung D, Jenal U, Levin B, Michiels J, Storz G, Tan M-W, Tenson T, Van Melderen L, Zinkernagel A. Definitions and guidelines for research on antibiotic persistence. Nat Rev Microbiol. 2019;17(7):441–448. PMCID: PMC7136161

Seyedsayamdost M. Toward a global picture of bacterial secondary metabolism. J Ind Microbiol Biotechnol. 2019;46(3-4):301–311. PMCID: PMC6779422

Aedo S, Ma H, Brynildsen M. Checks and Balances with Use of the Keio Collection for Phenotype Testing. Methods Mol Biol. 2019;1927:125–138. PMID: 30788789

Moon K, Xu F, Zhang C, Seyedsayamdost M. Bioactivity-HiTES Unveils Cryptic Antibiotics Encoded in Actinomycete Bacteria. ACS Chem Biol. 2019;14(4):767–774. PMCID: PMC6813803

Moon K, Xu F, Seyedsayamdost M. Cebulantin, a Cryptic Lanthipeptide Antibiotic Uncovered Using Bioactivity-Coupled HiTES. Angew Chem Int Ed Engl. 2019;58(18):5973–5977. PMCID: PMC6779416

Okada B, Li A, Seyedsayamdost M. Identification of the Hypertension Drug Guanfacine as an Antivirulence Agent in Pseudomonas aeruginosa. Chembiochem. 2019;20(15):2005–2011. PMCID: PMC6814388

Barrett T, Mok W, Murawski A, Brynildsen M. Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic. Nat Commun. 2019;10(1):1177. PMCID: PMC6414640

Cheung-Lee W, Parry M, Cartagena A, Darst S, Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019;294(17):6822–6830. PMCID: PMC6497930

Braffman N, Piscotta F, Hauver J, Campbell E, Link J, Darst S. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc Natl Acad Sci U S A. 2019;116(4):1273–1278. PMCID: PMC6347699

Yan J, Moreau A, Khodaparast S, Perazzo A, Feng J, Fei C, Mao S, Mukherjee S, Košmrlj A, Wingreen N, Bassler B, Stone H. Bacterial Biofilm Material Properties Enable Removal and Transfer by Capillary Peeling. Adv Mater. 2018;30(46):e1804153. PMCID: PMC8865467

Wu Y, Seyedsayamdost M. The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry. 2018;57(29):4247–4251. PMID: 29975047

Bratton B, Shaevitz J, Gitai Z, Morgenstein R. MreB polymers and curvature localization are enhanced by RodZ and predict E. coli’s cylindrical uniformity. Nat Commun. 2018;9(1):2797. PMCID: PMC6052060

Klaus J, Deay J, Neuenswander B, Hursh W, Gao Z, Bouddhara T, Williams T, Douglas J, Monize K, Martins P, Majerczyk C, Seyedsayamdost M, Peterson B, Rivera M, Chandler J. Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing. J Bacteriol. 2018;200(14). PMCID: PMC6018353

Metelev M, Arseniev A ii, Bushin L, Kuznedelov K, Artamonova T, Kondratenko R, Khodorkovskii M, Seyedsayamdost M, Severinov K. Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem Biol. 2017;12(3):814–824. PMID: 28106375

Okada B, Seyedsayamdost M. Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules. FEMS Microbiol Rev. 2017;41(1):19–33. PMCID: PMC5233716

Seyedsayamdost M. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proc Natl Acad Sci U S A. 2014;111(20):7266–71. PMCID: PMC4034229

Forneris C, Ozturk S, Gibson M, Sorensen E, Seyedsayamdost M. In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. ACS Chem Biol. 2017;12(9):2248–2253. PMCID: PMC5617736

Rosen P, Seyedsayamdost M. Though Much Is Taken, Much Abides: Finding New Antibiotics Using Old Ones. Biochemistry. 2017;56(37):4925–4926. PMCID: PMC5617734

Hoegler K, Hecht M. Artificial Gene Amplification in Escherichia coli Reveals Numerous Determinants for Resistance to Metal Toxicity. J Mol Evol. 2018;86(2):103–110. PMCID: PMC6116729

Liu G, Bratton B, Gitai Z, Shaevitz J. The effect of antibiotics on protein diffusion in the Escherichia coli cytoplasmic membrane. PLoS One. 2017;12(10):e0185810. PMCID: PMC5627921

Papenfort K, Bassler B. Quorum sensing signal-response systems in Gram-negative bacteria. Nat Rev Microbiol. 2016;14(9):576–88. PMCID: PMC5056591

Amato S, Brynildsen M. Persister Heterogeneity Arising from a Single Metabolic Stress. Curr Biol. 2015;25(16):2090–8. PMID: 26255847

Völzing K, Brynildsen M. Stationary-Phase Persisters to Ofloxacin Sustain DNA Damage and Require Repair Systems Only during Recovery. mBio. 2015;6(5):e00731–15. PMCID: PMC4556807

Orman M, Mok W, Brynildsen M. Aminoglycoside-enabled elucidation of bacterial persister metabolism. Curr Protoc Microbiol. 2015;36:17.9.1–17.9.14. PMCID: PMC4380151

Orman M, Henry T, DeCoste C, Brynildsen M. Analyzing Persister Physiology with Fluorescence-Activated Cell Sorting. Methods Mol Biol. 2016;1333:83–100. PMCID: PMC4908830