Implications of Big Data for cell biology.

TitleImplications of Big Data for cell biology.
Publication TypeJournal Article
Year of Publication2015
AuthorsDolinski, K, Troyanskaya, OG
JournalMol Biol Cell
Volume26
Issue14
Pagination2575-8
Date Published2015 Jul 15
ISSN1939-4586
KeywordsMolecular Biology, Systems Biology
Abstract

<p>"Big Data" has surpassed "systems biology" and "omics" as the hottest buzzword in the biological sciences, but is there any substance behind the hype? Certainly, we have learned about various aspects of cell and molecular biology from the many individual high-throughput data sets that have been published in the past 15-20 years. These data, although useful as individual data sets, can provide much more knowledge when interrogated with Big Data approaches, such as applying integrative methods that leverage the heterogeneous data compendia in their entirety. Here we discuss the benefits and challenges of such Big Data approaches in biology and how cell and molecular biologists can best take advantage of them. </p>

DOI10.1091/mbc.E13-12-0756
Alternate JournalMol. Biol. Cell
PubMed ID26174066
PubMed Central IDPMC4501356
Grant ListR01 GM071966 / GM / NIGMS NIH HHS / United States