Highly Potent, Chemically Stable Quorum Sensing Agonists for .
Publication Year
2014
Type
Journal Article
Abstract
In the pathogen, initiation of bacterial quorum sensing pathways serves to suppress virulence. We describe herein a potent and chemically stable small molecule agonist of quorum sensing, which was identified through rational drug design based on the native quorum sensing signal. This novel agonist may serve as a useful lead compound for the control of virulence in .
Journal
Chem Sci
Volume
5
Issue
1
Pages
151-155
Date Published
2014 Jan 01
ISSN Number
2041-6520
Alternate Journal
Chem Sci
PMCID
PMC3890260
PMID
24436778