Globularity and protein function.

Author
Publication Year
2000

Type

Journal Article
Abstract

Abstract The forces that direct protein folding lead naturally to native proteins and protein domains that are typically, to a first approximation, globular-spherical and compact, with a relatively clear distinction between the hydrophobic inside and polar outside. The near-universality of these features of protein structures sharpens our focus on some apparent exceptions. Consideration of the structure/function link in some of the exceptional cases provides some insights into our views of protein function.

Journal
J Biomol Struct Dyn
Volume
17 Suppl 1
Pages
87-8
Date Published
2000
ISSN Number
1538-0254
Alternate Journal
J Biomol Struct Dyn
PMID
22607410