Globularity and protein function. Author J Carey Publication Year 2000 Type Journal Article Abstract Abstract The forces that direct protein folding lead naturally to native proteins and protein domains that are typically, to a first approximation, globular-spherical and compact, with a relatively clear distinction between the hydrophobic inside and polar outside. The near-universality of these features of protein structures sharpens our focus on some apparent exceptions. Consideration of the structure/function link in some of the exceptional cases provides some insights into our views of protein function. Keywords Protein Structure, Tertiary, Protein Conformation, Protein Folding, Protein Structure, Secondary, Proteins, Hydrophobic and Hydrophilic Interactions Journal J Biomol Struct Dyn Volume 17 Suppl 1 Pages 87-8 Date Published 2000 ISSN Number 1538-0254 DOI 10.1080/07391102.2000.10506607 Alternate Journal J Biomol Struct Dyn PMID 22607410 PubMedGoogle ScholarBibTeXEndNote X3 XML