Genome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.

TitleGenome Sequence of the Virulent Model Herpes Simplex Virus 1 Strain McKrae Demonstrates the Presence of at Least Two Widely Used Variant Strains.
Publication TypeJournal Article
Year of Publication2021
AuthorsRenner, DW, Parsons, L, Shreve, JT, Engel, EA, Kuny, CV, Enquist, L, Neumann, D, Mangold, C, Szpara, ML
JournalMicrobiol Resour Announc
Volume10
Issue12
Date Published2021 Mar 25
ISSN2576-098X
Abstract

Herpes simplex virus 1 (HSV-1) strain McKrae was isolated in 1965 and has been utilized by many laboratories. Three HSV-1 strain McKrae stocks have been sequenced previously, revealing discrepancies in key genes. We sequenced the genome of HSV-1 strain McKrae from the laboratory of James M. Hill to better understand the genetic differences between isolates.
DOI10.1128/MRA.01146-19
Alternate JournalMicrobiol Resour Announc
PubMed ID33766904
PubMed Central IDPMC7996463
Grant ListR01 AI132692 / AI / NIAID NIH HHS / United States