Exploring and Exploiting Proteome Organization during Viral Infection.

Publication Year
2017

Type

Journal Article
Abstract

Viral replication in eukaryotes is a process inherently organized in both space and time. Viral components target subcellular organelles to access host machineries required for replication and spread. Diverse viruses are known to alter organelle shape, composition, function, and dynamics as part of their replication cycles. Here, we highlight recent advances in microscopy and proteomic methods that have helped and will continue to help define mechanisms used by viruses to exploit host proteome organization.

Journal
J Virol
Volume
91
Issue
18
Date Published
2017 Sep 15
ISSN Number
1098-5514
Alternate Journal
J Virol
PMCID
PMC5571249
PMID
28679763