Demographic and developmental patterns in telomere length across adolescence.

TitleDemographic and developmental patterns in telomere length across adolescence.
Publication TypeJournal Article
Year of Publication2020
AuthorsGaydosh, L, Mitchell, C, Notterman, D, Schneper, L, Brooks-Gunn, J, Wagner, B, Koss, K, McLanahan, S
JournalBiodemography Soc Biol
Volume66
Issue3-4
Pagination208-219
Date Published2020 Jul-Sep
ISSN1948-5573
KeywordsAdolescent, Adult, Biomarkers, Cellular Senescence, Child, Demography, Humans, Telomere, Telomere Shortening
Abstract

<p>Telomere length is often used in studies of adults as a biomarker of cellular aging and an indicator of stress exposure. However, we know little about how telomeres change over time, particularly over the course of the important developmental period of adolescence. We use data on telomere length collected at two points in time spanning adolescence (Years 9 and 15) from the Fragile Families and Child Wellbeing Study to examine longitudinal patterns ( = 1,654) in telomere length. We find a quantitatively small but significant average lengthening in telomere length across adolescence and little evidence of associations between telomere length and pubertal development.</p>

DOI10.1080/19485565.2021.1983758
Alternate JournalBiodemography Soc Biol
PubMed ID34597213
PubMed Central IDPMC8702463
Grant ListP2C HD042849 / HD / NICHD NIH HHS / United States
R01 HD076592 / HD / NICHD NIH HHS / United States
R01 MD011716 / MD / NIMHD NIH HHS / United States
R24 AG037898 / AG / NIA NIH HHS / United States