1.Bushin L, Seyedsayamdost M. Guidelines for Determining the Structures of Radical SAM Enzyme-Catalyzed Modifications in the Biosynthesis of RiPP Natural Products. Methods Enzymol. 2018;606:439–460. PMID: 30097102 Reference Link
1.Mao D, Okada B, Wu Y, Xu F, Seyedsayamdost M. Recent advances in activating silent biosynthetic gene clusters in bacteria. Curr Opin Microbiol. 2018;45:156–163. PMCID: PMC6281788 Reference Link
1.McRose D, Baars O, Seyedsayamdost M, Morel F. Quorum sensing and iron regulate a two-for-one siderophore gene cluster in . Proc Natl Acad Sci U S A. 2018;115(29):7581–7586. PMCID: PMC6055174 Reference Link
1.Wu Y, Seyedsayamdost M. The Polyene Natural Product Thailandamide A Inhibits Fatty Acid Biosynthesis in Gram-Positive and Gram-Negative Bacteria. Biochemistry. 2018;57(29):4247–4251. PMID: 29975047 Reference Link
1.Klaus J, Deay J, Neuenswander B, Hursh W, Gao Z, Bouddhara T, Williams T, Douglas J, Monize K, Martins P, Majerczyk C, Seyedsayamdost M, Peterson B, Rivera M, Chandler J. Malleilactone Is a Burkholderia pseudomallei Virulence Factor Regulated by Antibiotics and Quorum Sensing. J Bacteriol. 2018;200(14). PMCID: PMC6018353 Reference Link
1.Xu F, Nazari B, Moon K, Bushin L, Seyedsayamdost M. Discovery of a Cryptic Antifungal Compound from Streptomyces albus J1074 Using High-Throughput Elicitor Screens. J Am Chem Soc. 2017;139(27):9203–9212. PMCID: PMC5617735 Reference Link
1.Reece S, Seyedsayamdost M. Long-range proton-coupled electron transfer in the class Ia ribonucleotide reductase. Essays Biochem. 2017;61(2):281–292. PMID: 28487404 Reference Link
1.Mao D, Bushin L, Moon K, Wu Y, Seyedsayamdost M. Discovery of as a global regulator of secondary metabolism and virulence in E264. Proc Natl Acad Sci U S A. 2017;114(14):E2920-E2928. PMCID: PMC5389298 Reference Link
1.Schramma K, Seyedsayamdost M. Lysine-Tryptophan-Crosslinked Peptides Produced by Radical SAM Enzymes in Pathogenic Streptococci. ACS Chem Biol. 2017;12(4):922–927. PMID: 28191919 Reference Link
1.Metelev M, Arseniev A ii, Bushin L, Kuznedelov K, Artamonova T, Kondratenko R, Khodorkovskii M, Seyedsayamdost M, Severinov K. Acinetodin and Klebsidin, RNA Polymerase Targeting Lasso Peptides Produced by Human Isolates of Acinetobacter gyllenbergii and Klebsiella pneumoniae. ACS Chem Biol. 2017;12(3):814–824. PMID: 28106375 Reference Link
1.Okada B, Seyedsayamdost M. Antibiotic dialogues: induction of silent biosynthetic gene clusters by exogenous small molecules. FEMS Microbiol Rev. 2017;41(1):19–33. PMCID: PMC5233716 Reference Link
1.Okada B, Wu Y, Mao D, Bushin L, Seyedsayamdost M. Mapping the Trimethoprim-Induced Secondary Metabolome of Burkholderia thailandensis. ACS Chem Biol. 2016;11(8):2124–30. PMCID: PMC6786267 Reference Link
1.Wang R, Gallant Étienne, Seyedsayamdost M. Investigation of the Genetics and Biochemistry of Roseobacticide Production in the Roseobacter Clade Bacterium Phaeobacter inhibens. mBio. 2016;7(2):e02118. PMCID: PMC4807370 Reference Link
1.Baars O, Zhang X, Morel F, Seyedsayamdost M. The Siderophore Metabolome of Azotobacter vinelandii. Appl Environ Microbiol. 2016;82(1):27–39. PMCID: PMC4702634 Reference Link
1.Schramma K, Bushin L, Seyedsayamdost M. Structure and biosynthesis of a macrocyclic peptide containing an unprecedented lysine-to-tryptophan crosslink. Nat Chem. 2015;7(5):431–437. PMCID: PMC4443489 Reference Link
1.Seyedsayamdost M, Wang R, Kolter R, Clardy J. Hybrid biosynthesis of roseobacticides from algal and bacterial precursor molecules. J Am Chem Soc. 2014;136(43):15150–3. PMCID: PMC4227733 Reference Link
1.Seyedsayamdost M. High-throughput platform for the discovery of elicitors of silent bacterial gene clusters. Proc Natl Acad Sci U S A. 2014;111(20):7266–71. PMCID: PMC4034229 Reference Link
1.Nazari B, Forneris C, Gibson M, Moon K, Schramma K, Seyedsayamdost M. sp. ATCC 55076 harbours the largest actinomycete chromosome to date and the kistamicin biosynthetic gene cluster. Medchemcomm. 2017;8(4):780–788. PMCID: PMC5463735 Reference Link
1.Forneris C, Ozturk S, Gibson M, Sorensen E, Seyedsayamdost M. In Vitro Reconstitution of OxyA Enzymatic Activity Clarifies Late Steps in Vancomycin Biosynthesis. ACS Chem Biol. 2017;12(9):2248–2253. PMCID: PMC5617736 Reference Link
1.Rosen P, Seyedsayamdost M. Though Much Is Taken, Much Abides: Finding New Antibiotics Using Old Ones. Biochemistry. 2017;56(37):4925–4926. PMCID: PMC5617734 Reference Link
1.Davis K, Schramma K, Hansen W, Bacik J, Khare S, Seyedsayamdost M, Ando N. Structures of the peptide-modifying radical SAM enzyme SuiB elucidate the basis of substrate recognition. Proc Natl Acad Sci U S A. 2017;114(39):10420–10425. PMCID: PMC5625900 Reference Link
1.Wang R, Seyedsayamdost M. Roseochelin B, an Algaecidal Natural Product Synthesized by the Roseobacter Phaeobacter inhibens in Response to Algal Sinapic Acid. Org Lett. 2017;19(19):5138–5141. PMID: 28920692 Reference Link
1.Wu Y, Seyedsayamdost M. Synergy and Target Promiscuity Drive Structural Divergence in Bacterial Alkylquinolone Biosynthesis. Cell Chem Biol. 2017;24(12):1437–1444.e3. PMCID: PMC5741510 Reference Link
1.Baars O, Zhang X, Gibson M, Stone A, Morel F, Seyedsayamdost M. Crochelins: Siderophores with an Unprecedented Iron-Chelating Moiety from the Nitrogen-Fixing Bacterium Azotobacter chroococcum. Angew Chem Int Ed Engl. 2018;57(2):536–541. PMID: 29134779 Reference Link
1.Schramma K, Forneris C, Caruso A, Seyedsayamdost M. Mechanistic Investigations of Lysine-Tryptophan Cross-Link Formation Catalyzed by Streptococcal Radical S-Adenosylmethionine Enzymes. Biochemistry. 2018;57(4):461–468. PMID: 29320164 Reference Link
1.Papenfort K, Silpe J, Schramma K, Cong J-P, Seyedsayamdost M, Bassler B. A Vibrio cholerae autoinducer-receptor pair that controls biofilm formation. Nat Chem Biol. 2017;13(5):551–557. PMCID: PMC5391282 Reference Link
1.Seyedsayamdost M, Xie J, T Y Chan C, Schultz P, Stubbe J. Site-specific insertion of 3-aminotyrosine into subunit alpha2 of E. coli ribonucleotide reductase: direct evidence for involvement of Y730 and Y731 in radical propagation. J Am Chem Soc. 2007;129(48):15060–71. PMID: 17990884 Reference Link
1.Seyedsayamdost M, Argirević T, Minnihan E, Stubbe J, Bennati M. Structural examination of the transient 3-aminotyrosyl radical on the PCET pathway of E. coli ribonucleotide reductase by multifrequency EPR spectroscopy. J Am Chem Soc. 2009;131(43):15729–38. PMCID: PMC4703294 Reference Link
1.Seyedsayamdost M, Chandler J, Blodgett J, Lima P, Duerkop B, Oinuma K-I, Greenberg P, Clardy J. Quorum-sensing-regulated bactobolin production by Burkholderia thailandensis E264. Org Lett. 2010;12(4):716–9. PMCID: PMC2821070 Reference Link
1.Seyedsayamdost M, Cleto S, Carr G, Vlamakis H, Vieira M, Kolter R, Clardy J. Mixing and matching siderophore clusters: structure and biosynthesis of serratiochelins from Serratia sp. V4. J Am Chem Soc. 2012;134(33):13550–3. PMCID: PMC3424848 Reference Link
1.Seyedsayamdost M, Case R, Kolter R, Clardy J. The Jekyll-and-Hyde chemistry of Phaeobacter gallaeciensis. Nat Chem. 2011;3(4):331–5. PMCID: PMC3376411 Reference Link
1.Seyedsayamdost M, Traxler M, Zheng S-L, Kolter R, Clardy J. Structure and biosynthesis of amychelin, an unusual mixed-ligand siderophore from Amycolatopsis sp. AA4. J Am Chem Soc. 2011;133(30):11434–7. PMCID: PMC3144690 Reference Link
1.Wilson M, Wang R, Gitai Z, Seyedsayamdost M. Mode of action and resistance studies unveil new roles for tropodithietic acid as an anticancer agent and the γ-glutamyl cycle as a proton sink. Proc Natl Acad Sci U S A. 2016;113(6):1630–5. PMCID: PMC4760781 Reference Link