1.Cappuccio A, Chawla D, Chen X, Rubenstein A, Cheng W, Mao W, Burke T, Tsalik E, Petzold E, Henao R, McClain M, Woods C, Chikina M, Troyanskaya O, Sealfon S, Kleinstein S, Zaslavsky E. Multi-objective optimization identifies a specific and interpretable COVID-19 host response signature. Cell Syst. 2022;13(12):989–1001.e8. PMID: 36549275 Reference Link
1.Sauerwald N, Zhang Z, Ramos I, Nair V, Soares-Schanoski A, Ge Y, Mao W, Alshammary H, Gonzalez-Reiche A, van de Guchte A, Goforth C, Lizewski R, Lizewski S, Amper M, Vasoya M, Seenarine N, Guevara K, Marjanovic N, Miller C, Nudelman G, Schilling M, Sealfon R, Termini M, Vangeti S, Weir D, Zaslavsky E, Chikina M, Wu Y, van Bakel H, Letizia A, Sealfon S, Troyanskaya O. Pre-infection antiviral innate immunity contributes to sex differences in SARS-CoV-2 infection. Cell Syst. 2022;13(11):924–931.e4. PMCID: PMC9623453 Reference Link
1.Lizewski R, Sealfon R, Park S, Smith G, Porter C, Gonzalez-Reiche A, Ge Y, Miller C, Goforth C, Pincas H, Termini M, Ramos I, Nair V, Lizewski S, Alshammary H, Cer R, Chen H, George M-C, Arnold C, Glang L, Long K, Malagon F, Marayag J, Nunez E, Rice G, Ana E, Schilling M, Smith D, Sugiharto V, Sun P, van de Guchte A, Khan Z, Dutta J, Vangeti S, Voegtly L, Weir D, Metcalf J, Troyanskaya O, Bishop-Lilly K, Grenfell B, van Bakel H, Letizia A, Sealfon S. SARS-CoV-2 Outbreak Dynamics in an Isolated US Military Recruit Training Center With Rigorous Prevention Measures. Epidemiology. 2022;33(6):797–807. PMCID: PMC9531985 Reference Link
1.Soares-Schanoski A, Sauerwald N, Goforth C, Periasamy S, Weir D, Lizewski S, Lizewski R, Ge Y, Kuzmina N, Nair V, Vangeti S, Marjanovic N, Cappuccio A, Cheng W, Mofsowitz S, Miller C, Yu X, George M-C, Zaslavsky E, Bukreyev A, Troyanskaya O, Sealfon S, Letizia A, Ramos I. Asymptomatic SARS-CoV-2 Infection Is Associated With Higher Levels of Serum IL-17C, Matrix Metalloproteinase 10 and Fibroblast Growth Factors Than Mild Symptomatic COVID-19. Front Immunol. 2022;13:821730. PMCID: PMC9037090 Reference Link
1.Zhang Z, Zamojski M, Smith G, Willis T, Yianni V, Mendelev N, Pincas H, Seenarine N, Amper M, Vasoya M, Cheng W, Zaslavsky E, Nair V, Turgeon J, Bernard D, Troyanskaya O, Andoniadou C, Sealfon S, Ruf-Zamojski F. Single nucleus transcriptome and chromatin accessibility of postmortem human pituitaries reveal diverse stem cell regulatory mechanisms. Cell Rep. 2022;38(10):110467. PMCID: PMC8957708 Reference Link
1.Meyer M, Wang Y, Edwards D, Smith G, Rubenstein A, Ramanathan P, Mire C, Pietzsch C, Chen X, Ge Y, Cheng W, Henry C, Woods A, Ma L, Stewart-Jones G, Bock K, Minai M, Nagata B, Periasamy S, Shi P-Y, Graham B, Moore I, Ramos I, Troyanskaya O, Zaslavsky E, Carfi A, Sealfon S, Bukreyev A. Attenuated activation of pulmonary immune cells in mRNA-1273-vaccinated hamsters after SARS-CoV-2 infection. J Clin Invest. 2021;131(20). PMCID: PMC8516449 Reference Link
1.Ruf-Zamojski F, Zhang Z, Zamojski M, Smith G, Mendelev N, Liu H, Nudelman G, Moriwaki M, Pincas H, Castanon R, Nair V, Seenarine N, Amper M, Zhou X, Ongaro L, Toufaily C, Schang G, Nery J, Bartlett A, Aldridge A, Jain N, Childs G, Troyanskaya O, Ecker J, Turgeon J, Welt C, Bernard D, Sealfon S. Single nucleus multi-omics regulatory landscape of the murine pituitary. Nat Commun. 2021;12(1):2677. PMCID: PMC8113460 Reference Link
1.Letizia A, Ramos I, Obla A, Goforth C, Weir D, Ge Y, Bamman M, Dutta J, Ellis E, Estrella L, George M-C, Gonzalez-Reiche A, Graham W, van de Guchte A, Gutierrez R, Jones F, Kalomoiri A, Lizewski R, Lizewski S, Marayag J, Marjanovic N, Millar E, Nair V, Nudelman G, Nunez E, Pike B, Porter C, Regeimbal J, Rirak S, Ana E, Sealfon R, Sebra R, Simons M, Soares-Schanoski A, Sugiharto V, Termini M, Vangeti S, Williams C, Troyanskaya O, van Bakel H, Sealfon S. SARS-CoV-2 Transmission among Marine Recruits during Quarantine. N Engl J Med. 2020;383(25):2407–2416. PMCID: PMC7675690 Reference Link
1.Lee Y-S, Wong A, Tadych A, Hartmann B, Park C, DeJesus V, Ramos I, Zaslavsky E, Sealfon S, Troyanskaya O. Interpretation of an individual functional genomics experiment guided by massive public data. Nat Methods. 2018;15(12):1049–1052. PMCID: PMC6941785 Reference Link
1.Chikina M, Gerald C, Li X, Ge Y, Pincas H, Nair V, Wong A, Krishnan A, Troyanskaya O, Raymond D, Saunders-Pullman R, Bressman S, Yue Z, Sealfon S. Low-variance RNAs identify Parkinson’s disease molecular signature in blood. Mov Disord. 2015;30(6):813–21. PMCID: PMC4439364 Reference Link
1.Gorenshteyn D, Zaslavsky E, Fribourg M, Park C, Wong A, Tadych A, Hartmann B, Albrecht R, García-Sastre A, Kleinstein S, Troyanskaya O, Sealfon S. Interactive Big Data Resource to Elucidate Human Immune Pathways and Diseases. Immunity. 2015;43(3):605–14. PMCID: PMC4753773 Reference Link