Johnson M, Li S, Guerrero-Juarez C, Miller P, Brack B, Mereby S, Moreno J, Feigin C, Gaska J, Rivera-Perez J, Nie Q, Ploss A, Shvartsman S, Mallarino R. A multifunctional Wnt regulator underlies the evolution of rodent stripe patterns. Nature ecology & evolution. 2023;7(12):2143–2159. PMCID: PMC10839778

Moreno J, Dudchenko O, Feigin C, Mereby S, Chen Z, Ramos R, Almet A, Sen H, Brack B, Johnson M, Li S, Wang W, Gaska J, Ploss A, Weisz D, Omer A, Yao W, Colaric Z, Kaur P, St Leger J, Nie Q, Mena A, Flanagan J, Keller G, Sanger T, Ostrow B, Plikus M V, Kvon E, Aiden E, Mallarino R. Emx2 underlies the development and evolution of marsupial gliding membranes. Nature. 2024;629(8010):127–135. PMCID: PMC11062917

LeDesma R, Heller B, Biswas A, Maya S, Gili S, Higgins J, Ploss A. Structural features stabilized by divalent cation coordination within hepatitis E virus ORF1 are critical for viral replication. Elife. 2023;12. PMCID: PMC9977285

Testoni B, Ploss A. Cracking the host functional network involved in hepatitis B virus cccDNA biology. Gut. 2023;. PMID: 36707232

Douam F, Ploss A. A humanized "new-trophil" mouse to study early inflammatory processes. Proc Natl Acad Sci U S A. 2022;119(49):e2216699119. PMCID: PMC9894160

Schwoerer M, Ploss A. Barriers to hepatitis C virus infection in mice. Curr Opin Virol. 2022;56:101273. PMID: 36244239

Suzuki S, Geri J, Knutson S, Bell-Temin H, Tamura T, Fernández D, Lovett G, Till N, Heller B, Guo J, MacMillan D, Ploss A. Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap. J Am Chem Soc. 2022;144(36):16604–16611. PMCID: PMC9469761

Wei L, Cafiero T, Tseng A, Gertje H, Berneshawi A, Crossland N, Ploss A. Conversion of hepatitis B virus relaxed circular to covalently closed circular DNA is supported in murine cells. JHEP Rep. 2022;4(9):100534. PMCID: PMC9403495

Liu Y, Park D, Cafiero T, Bram Y, Chandar V, Tseng A, Gertje H, Crossland N, Su L, Schwartz R, Ploss A. Molecular clones of genetically distinct hepatitis B virus genotypes reveal distinct host and drug treatment responses. JHEP Rep. 2022;4(9):100535. PMCID: PMC9403497

Biswas S, Rust L, Wettengel J, Yusova S, Fischer M, Carson J, Johnson J, Wei L, Thode T, Kaadige M, Sharma S, Agbaria M, Bimber B, Tu T, Protzer U, Ploss A, Smedley J, Golomb G, Sacha J, Burwitz B. Long-term hepatitis B virus infection of rhesus macaques requires suppression of host immunity. Nat Commun. 2022;13(1):2995. PMCID: PMC9151762

Kenney D, O’Connell A, Turcinovic J, Montanaro P, Hekman R, Tamura T, Berneshawi A, Cafiero T, Abdullatif S, Blum B, Goldstein S, Heller B, Gertje H, Bullitt E, Trachtenberg A, Chavez E, Nono E, Morrison C, Tseng A, Sheikh A, Kurnick S, Grosz K, Bosmann M, Ericsson M, Huber B, Saeed M, Balazs A, Francis K, Klose A, Paragas N, Campbell J, Connor J, Emili A, Crossland N, Ploss A, Douam F. Humanized mice reveal a macrophage-enriched gene signature defining human lung tissue protection during SARS-CoV-2 infection. Cell Rep. 2022;39(3):110714. PMCID: PMC8977517

Buksh B, Knutson S, Oakley J, Bissonnette N, Oblinsky D, Schwoerer M, Seath C, Geri J, Rodriguez-Rivera F, Parker D, Scholes G, Ploss A, MacMillan D. μMap-Red: Proximity Labeling by Red Light Photocatalysis. J Am Chem Soc. 2022;144(14):6154–6162. PMCID: PMC9843638

Wang R, Suzuki S, Guest J, Heller B, Almeda M, Andrianov A, Marin A, Mariuzza R, Keck Z-Y, Foung S, Yunus A, Pierce B, Toth E, Ploss A, Fuerst T. Induction of broadly neutralizing antibodies using a secreted form of the hepatitis C virus E1E2 heterodimer as a vaccine candidate. Proc Natl Acad Sci U S A. 2022;119(11):e2112008119. PMCID: PMC8931252

Shekhtman L, Cotler S, Ploss A, Dahari H. Mathematical modeling suggests that entry-inhibitor bulevirtide may interfere with hepatitis D virus clearance from circulation. J Hepatol. 2022;76(5):1229–1231. PMCID: PMC9018506

Tamura T, Zhang J, Madan V, Biswas A, Schwoerer M, Cafiero T, Heller B, Wang W, Ploss A. Generation and characterization of genetically and antigenically diverse infectious clones of dengue virus serotypes 1-4. Emerg Microbes Infect. 2022;11(1):227–239. PMCID: PMC8745371

Wei L, Ploss A. Rise above the stress-Endoplasmic reticulum stress and autophagy enhance the release of hepatitis B virus subparticles. Hepatology. 2022;75(2):248–251. PMID: 34890054

Wei L, Ploss A. Mechanism of Hepatitis B Virus cccDNA Formation. Viruses. 2021;13(8). PMCID: PMC8402782

Liu Y, Maya S, Ploss A. Animal Models of Hepatitis B Virus Infection-Success, Challenges, and Future Directions. Viruses. 2021;13(5). PMCID: PMC8146732

Sanders D, Jumper C, Ackerman P, Bracha D, Donlic A, Kim H, Kenney D, Castello-Serrano I, Suzuki S, Tamura T, Tavares A, Saeed M, Holehouse A, Ploss A, Levental I, Douam F, Padera R, Levy B, Brangwynne C. SARS-CoV-2 requires cholesterol for viral entry and pathological syncytia formation. Elife. 2021;10. PMCID: PMC8104966

Wei L, Ploss A. Hepatitis B virus cccDNA is formed through distinct repair processes of each strand. Nat Commun. 2021;12(1):1591. PMCID: PMC7952586

Nimgaonkar I, Archer N, Becher I, Shahrad M, LeDesma R, Mateus A, Caballero-Gómez J, Berneshawi A, Ding Q, Douam F, Gaska J, Savitski M, Kim H, Ploss A. Isocotoin suppresses hepatitis E virus replication through inhibition of heat shock protein 90. Antiviral Res. 2021;185:104997. PMCID: PMC8649941

Ploss A, Strick-Marchand H, Li W. Animal Models for Hepatitis B: Does the Supply Meet the Demand?. Gastroenterology. 2021;160(5):1437–1442. PMCID: PMC8035324

Brown R, Tegtmeyer B, Sheldon J, Khera T, Todt D, Vieyres G, Weller R, Joecks S, Zhang Y, Sake S, Bankwitz D, Welsch K, Ginkel C, Engelmann M, Gerold G, Steinmann E, Yuan Q, Ott M, Vondran F, Krey T, Ströh L, Miskey C, Ivics Z, Herder V, Baumgärtner W, Lauber C, Seifert M, Tarr A, McClure P, Randall G, Baktash Y, Ploss A, Thi V, Michailidis E, Saeed M, Verhoye L, Meuleman P, Goedecke N, Wirth D, Rice C, Pietschmann T. Liver-expressed and limit hepatitis C virus cross-species transmission to mice. Sci Adv. 2020;6(45). PMCID: PMC7673688

LeDesma R, Nimgaonkar I, Ploss A. Hepatitis E Virus Replication. Viruses. 2019;11(8). PMCID: PMC6723718

Berggren K, Suzuki S, Ploss A. Animal Models Used in Hepatitis C Virus Research. Int J Mol Sci. 2020;21(11). PMCID: PMC7312079

Ramanathan H, Zhang S, Douam F, Mar K, Chang J, Yang P, Schoggins J, Ploss A, Lindenbach B. A Sensitive Yellow Fever Virus Entry Reporter Identifies Valosin-Containing Protein (VCP/p97) as an Essential Host Factor for Flavivirus Uncoating. mBio. 2020;11(2). PMCID: PMC7157815

Chen C, Winer B, Chavez D, Guerra B, Brasky K, Eng S, Salas E, Tam D, Simmons J, Abee C, Delaney W, Ploss A, Lanford R, Voitenleitner C. Woolly Monkey-HBV Infection in Squirrel Monkeys as a Surrogate Nonhuman Primate Model of HBV Infection. Hepatol Commun. 2020;4(3):371–386. PMCID: PMC7049680

Wei L, Ploss A. Core components of DNA lagging strand synthesis machinery are essential for hepatitis B virus cccDNA formation. Nat Microbiol. 2020;5(5):715–726. PMCID: PMC7190442

Winer B, Edgel K, Zou X, Sellau J, Hadiwidjojo S, Garver L, McDonough C, Kelleher N, Thomas P, Villasante E, Ploss A, Gerbasi V. Identification of Plasmodium falciparum proteoforms from liver stage models. Malar J. 2020;19(1):10. PMCID: PMC6947969

Akkina R, Barber D, Bility M, Bissig K-D, Burwitz B, Eichelberg K, Endsley J, Garcia V, Hafner R, Karakousis P, Korba B, Koshy R, Lambros C, Menne S, Nuermberger E, Ploss A, Podell B, Poluektova L, Sanders-Beer B, Subbian S, Wahl A. Small Animal Models for Human Immunodeficiency Virus (HIV), Hepatitis B, and Tuberculosis: Proceedings of an NIAID Workshop. Curr HIV Res. 2020;18(1):19–28. PMCID: PMC7403688

Ploss A, Kapoor A. Animal Models of Hepatitis C Virus Infection. Cold Spring Harb Perspect Med. 2020;10(5). PMCID: PMC7197424

Gaska J, Parsons L, Balev M, Cirincione A, Wang W, Schwartz R, Ploss A. Conservation of cell-intrinsic immune responses in diverse nonhuman primate species. Life Sci Alliance. 2019;2(5). PMCID: PMC6814850

Maya S, Ploss A. Master of Disguise: Hepatitis Delta Virus Packaging and Spread Facilitated by Diverse Viral Envelope Proteins. Hepatology. 2020;71(1):380–382. PMID: 31465549

Winer B, Gaska J, Lipkowitz G, Bram Y, Parekh A, Parsons L, Leach R, Jindal R, Cho C, Shrirao A, Novik E, Schwartz R, Ploss A. Analysis of Host Responses to Hepatitis B and Delta Viral Infections in a Micro-scalable Hepatic Co-culture System. Hepatology. 2020;71(1):14–30. PMCID: PMC6917996

Gaska J, Balev M, Ding Q, Heller B, Ploss A. Differences across cyclophilin A orthologs contribute to the host range restriction of hepatitis C virus. Elife. 2019;8. PMCID: PMC6510530

Mesev E, LeDesma R, Ploss A. Decoding type I and III interferon signalling during viral infection. Nat Microbiol. 2019;4(6):914–924. PMCID: PMC6554024

Gaska J, Ding Q, Ploss A. Mouse Models for Studying HCV Vaccines and Therapeutic Antibodies. Methods Mol Biol. 2019;1911:481–503. PMCID: PMC6699619

Douam F, Ziegler C, Hrebikova G, Fant B, Leach R, Parsons L, Wang W, Gaska J, Winer B, Heller B, Shalek A, Ploss A. Selective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses. Nat Commun. 2018;9(1):5031. PMCID: PMC6262001

Winer B, Shirvani-Dastgerdi E, Bram Y, Sellau J, Low B, Johnson H, Huang T, Hrebikova G, Heller B, Sharon Y, Giersch K, Gerges S, Seneca K, Pais M-A, Frankel A, Chiriboga L, Cullen J, Nahass R, Lutgehetmann M, Toettcher J, Wiles M, Schwartz R, Ploss A. Preclinical assessment of antiviral combination therapy in a genetically humanized mouse model for hepatitis delta virus infection. Sci Transl Med. 2018;10(447). PMCID: PMC6337727

Ding Q, Gaska J, Douam F, Wei L, Kim D, Balev M, Heller B, Ploss A. Species-specific disruption of STING-dependent antiviral cellular defenses by the Zika virus NS2B3 protease. Proc Natl Acad Sci U S A. 2018;115(27):E6310-E6318. PMCID: PMC6142274

Douam F, Ploss A. Yellow Fever Virus: Knowledge Gaps Impeding the Fight Against an Old Foe. Trends Microbiol. 2018;26(11):913–928. PMCID: PMC6340642

Ding Q, Nimgaonkar I, Archer N, Bram Y, Heller B, Schwartz R, Ploss A. Identification of the Intragenomic Promoter Controlling Hepatitis E Virus Subgenomic RNA Transcription. mBio. 2018;9(3). PMCID: PMC5941075

Dragovic S, Agunbiade T, Freudzon M, Yang J, Hastings A, Schleicher T, Zhou X, Craft S, Chuang Y-M, Gonzalez F, Li Y, Hrebikova G, Tripathi A, Mlambo G, Almeras L, Ploss A, Dimopoulos G, Fikrig E. Immunization with AgTRIO, a Protein in Anopheles Saliva, Contributes to Protection against Plasmodium Infection in Mice. Cell Host Microbe. 2018;23(4):523–535.e5. PMCID: PMC5998332

Douam F, Ploss A. The use of humanized mice for studies of viral pathogenesis and immunity. Curr Opin Virol. 2018;29:62–71. PMCID: PMC5940492

Douam F, Fusil F, Enguehard M, Dib L, Nadalin F, Schwaller L, Hrebikova G, Mancip J, Mailly L, Montserret R, Ding Q, Maisse C, Carlot E, Xu K, Verhoeyen E, Baumert T, Ploss A, Carbone A, Cosset F-L, Lavillette D. A protein coevolution method uncovers critical features of the Hepatitis C Virus fusion mechanism. PLoS Pathog. 2018;14(3):e1006908. PMCID: PMC5854445

Nimgaonkar I, Ding Q, Schwartz R, Ploss A. Hepatitis E virus: advances and challenges. Nat Rev Gastroenterol Hepatol. 2018;15(2):96–110. PMID: 29162935

Nimgaonkar I, Ploss A. A porcine model for chronic hepatitis E. Hepatology. 2018;67(2):787–790. PMID: 28961321

Douam F, Albrecht Y, Hrebikova G, Sadimin E, Davidson C, Kotenko S, Ploss A. Type III Interferon-Mediated Signaling Is Critical for Controlling Live Attenuated Yellow Fever Virus Infection . mBio. 2017;8(4). PMCID: PMC5559630

Winer B, Huang T, Pludwinski E, Heller B, Wojcik F, Lipkowitz G, Parekh A, Cho C, Shrirao A, Muir T, Novik E, Ploss A. Long-term hepatitis B infection in a scalable hepatic co-culture system. Nat Commun. 2017;8(1):125. PMCID: PMC5527081

Li D, Wang X, von Schaewen M, Tao W, Zhang Y, Heller B, Hrebikova G, Deng Q, Sun Q, Ploss A, Zhong J, Huang Z. Immunization With a Subunit Hepatitis C Virus Vaccine Elicits Pan-Genotypic Neutralizing Antibodies and Intrahepatic T-Cell Responses in Nonhuman Primates. J Infect Dis. 2017;215(12):1824–1831. PMCID: PMC5853543