1.Cota V, Sohrabi S, Kaletsky R, Murphy C. Oocyte mitophagy is critical for extended reproductive longevity. PLoS Genet. 2022;18(9):e1010400. PMCID: PMC9524673 Reference Link
1.McIntyre L, Huertas F, Morse A, Kaletsky R, Murphy C, Kalia V, Miller G, Moskalenko O, Conesa A, Mor D. GAIT-GM integrative cross-omics analyses reveal cholinergic defects in a C. elegans model of Parkinson’s disease. Sci Rep. 2022;12(1):3268. PMCID: PMC8885929 Reference Link
1.Rahimi M, Sohrabi S, Murphy C. Novel elasticity measurements reveal C. elegans cuticle stiffens with age and in a long-lived mutant. Biophys J. 2022;121(4):515–524. PMCID: PMC8874029 Reference Link
1.Sohrabi S, Moore R, Murphy C. CeAid: a smartphone application for logging and plotting Caenorhabditis elegans assays. G3 (Bethesda). 2021;11(10). PMCID: PMC8473968 Reference Link
1.Sohrabi S, Mor D, Kaletsky R, Keyes W, Murphy C. High-throughput behavioral screen in C. elegans reveals Parkinson’s disease drug candidates. Commun Biol. 2021;4(1):203. PMCID: PMC7884385 Reference Link
1.Baumeister R, Murphy C, Heimbucher T. Metabolic adaptation to hypoxia: do worms and cancer cells share common metabolic responses to hypoxic stress?. Cell Death Differ. 2021;28(4):1434–1436. PMCID: PMC8026991 Reference Link
1.Moore R, Kaletsky R, Lesnik C, Cota V, Blackman E, Parsons L, Gitai Z, Murphy C. The role of the Cer1 transposon in horizontal transfer of transgenerational memory. Cell. 2021;184(18):4697–4712.e18. PMCID: PMC8812995 Reference Link
1.Choi L, Shi C, Ashraf J, Sohrabi S, Murphy C. Oleic Acid Protects Mothers From Mating-Induced Death and the Cost of Reproduction. Front Cell Dev Biol. 2021;9:690373. PMCID: PMC8226236 Reference Link
1.Moore R, Kaletsky R, Murphy C. Protocol for transgenerational learned pathogen avoidance behavior assays in . STAR Protoc. 2021;2(1):100384. PMCID: PMC7960678 Reference Link
1.Lee Y, Jung Y, Jeong D-E, Hwang W, Ham S, Park H-E, Kwon S, Ashraf J, Murphy C, Lee S-J. Reduced insulin/IGF1 signaling prevents immune aging via ZIP-10/bZIP-mediated feedforward loop. J Cell Biol. 2021;220(5). PMCID: PMC7941181 Reference Link
1.Heimbucher T, Hog J, Gupta P, Murphy C. Author Correction: PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020;11(1):6018. PMCID: PMC7680132 Reference Link
1.Mor D, Murphy C. Mitochondrial hyperactivity as a potential therapeutic target in Parkinson’s disease. Transl Med Aging. 2020;4:117–120. PMCID: PMC7653964 Reference Link
1.Heimbucher T, Hog J, Gupta P, Murphy C. PQM-1 controls hypoxic survival via regulation of lipid metabolism. Nat Commun. 2020;11(1):4627. PMCID: PMC7532158 Reference Link
1.Mor D, Sohrabi S, Kaletsky R, Keyes W, Tartici A, Kalia V, Miller G, Murphy C. Metformin rescues Parkinson’s disease phenotypes caused by hyperactive mitochondria. Proc Natl Acad Sci U S A. 2020;117(42):26438–26447. PMCID: PMC7585014 Reference Link
1.Kaletsky R, Moore R, Vrla G, Parsons L, Gitai Z, Murphy C. C. elegans interprets bacterial non-coding RNAs to learn pathogenic avoidance. Nature. 2020;586(7829):445–451. PMCID: PMC8547118 Reference Link
1.Templeman N, Cota V, Keyes W, Kaletsky R, Murphy C. CREB Non-autonomously Controls Reproductive Aging through Hedgehog/Patched Signaling. Dev Cell. 2020;54(1):92–105.e5. PMCID: PMC7837322 Reference Link
1.Kaletsky R, Murphy C. Transcriptional Profiling of C. elegans Adult Cells and Tissues with Age. Methods Mol Biol. 2020;2144:177–186. PMID: 32410035 Reference Link
1.Arey R, Kaletsky R, Murphy C. Nervous system-wide profiling of presynaptic mRNAs reveals regulators of associative memory. Sci Rep. 2019;9(1):20314. PMCID: PMC6937282 Reference Link
1.Murphy C. Being open to the unexpected. Mol Biol Cell. 2019;30(23):2862–2864. PMCID: PMC6822587 Reference Link
1.Shi C, Booth L, Murphy C. Insulin-like peptides and the mTOR-TFEB pathway protect hermaphrodites from mating-induced death. Elife. 2019;8. PMCID: PMC6697448 Reference Link
1.Moore R, Kaletsky R, Murphy C. Piwi/PRG-1 Argonaute and TGF-β Mediate Transgenerational Learned Pathogenic Avoidance. Cell. 2019;177(7):1827–1841.e12. PMCID: PMC7518193 Reference Link
1.Heimbucher T, Murphy C. A PBX/MEIS Complex Balances Reproduction and Somatic Resilience. Dev Cell. 2019;49(2):157–158. PMCID: PMC7452753 Reference Link
1.Tabuchi T, Rechtsteiner A, Jeffers T, Egelhofer T, Murphy C, Strome S. Caenorhabditis elegans sperm carry a histone-based epigenetic memory of both spermatogenesis and oogenesis. Nat Commun. 2018;9(1):4310. PMCID: PMC6193031 Reference Link
1.Yao V, Kaletsky R, Keyes W, Mor D, Wong A, Sohrabi S, Murphy C, Troyanskaya O. An integrative tissue-network approach to identify and test human disease genes. Nat Biotechnol. 2018;. PMCID: PMC7021177 Reference Link
1.Heimbucher T, Murphy C. Investigating Mechanisms that Control Ubiquitin-Mediated DAF-16/FOXO Protein Turnover. Methods Mol Biol. 2019;1890:41–49. PMCID: PMC8428773 Reference Link
1.Kaletsky R, Yao V, Williams A, Runnels A, Tadych A, Zhou S, Troyanskaya O, Murphy C. Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression. PLoS Genet. 2018;14(8):e1007559. PMCID: PMC6105014 Reference Link
1.Arey R, Stein G, Kaletsky R, Kauffman A, Murphy C. Activation of G Signaling Enhances Memory Consolidation and Slows Cognitive Decline. Neuron. 2018;98(3):562–574.e5. PMCID: PMC5934306 Reference Link
1.Templeman N, Luo S, Kaletsky R, Shi C, Ashraf J, Keyes W, Murphy C. Insulin Signaling Regulates Oocyte Quality Maintenance with Age via Cathepsin B Activity. Curr Biol. 2018;28(5):753–760.e4. PMCID: PMC5893159 Reference Link
1.Templeman N, Murphy C. Regulation of reproduction and longevity by nutrient-sensing pathways. J Cell Biol. 2018;217(1):93–106. PMCID: PMC5748989 Reference Link
1.Shi C, Runnels A, Murphy C. Mating and male pheromone kill males through distinct mechanisms. Elife. 2017;6. PMCID: PMC5378475 Reference Link
1.Son H, Seo M, Ham S, Hwang W, Lee D, An S, Artan M, Seo K, Kaletsky R, Arey R, Ryu Y, Ha C, Kim Y, Murphy C, Roh T-Y, Nam H, Lee S-J. RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans. Nat Commun. 2017;8:14749. PMCID: PMC5347137 Reference Link
1.Lakhina V, Murphy C. Genome Sequencing Fishes out Longevity Genes. Cell. 2015;163(6):1312–3. PMID: 26638067 Reference Link
1.Hahm J-H, Kim S, DiLoreto R, Shi C, Lee S-J, Murphy C, Nam H. C. elegans maximum velocity correlates with healthspan and is maintained in worms with an insulin receptor mutation. Nat Commun. 2015;6:8919. PMCID: PMC4656132 Reference Link
1.DiLoreto R, Murphy C. The cell biology of aging. Mol Biol Cell. 2015;26(25):4524–31. PMCID: PMC4678010 Reference Link
1.Crocker A, Guan X-J, Murphy C, Murthy M. Cell-Type-Specific Transcriptome Analysis in the Drosophila Mushroom Body Reveals Memory-Related Changes in Gene Expression. Cell Rep. 2016;15(7):1580–1596. PMCID: PMC5047377 Reference Link
1.Kaletsky R, Lakhina V, Arey R, Williams A, Landis J, Ashraf J, Murphy C. The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators. Nature. 2016;529(7584):92–6. PMCID: PMC4708089 Reference Link
1.Wang J, Kaletsky R, Silva M, Williams A, Haas L, Androwski R, Landis J, Patrick C, Rashid A, Santiago-Martinez D, Gravato-Nobre M, Hodgkin J, Hall D, Murphy C, Barr M. Cell-Specific Transcriptional Profiling of Ciliated Sensory Neurons Reveals Regulators of Behavior and Extracellular Vesicle Biogenesis. Curr Biol. 2015;25(24):3232–8. PMCID: PMC4698341 Reference Link
1.Shi C, Murphy C. Feeding the germline. Genes Dev. 2016;30(3):249–50. PMCID: PMC4743054 Reference Link
1.Li L-B, Lei H, Arey R, Li P, Liu J, Murphy C, Xu X, Shen K. The Neuronal Kinesin UNC-104/KIF1A Is a Key Regulator of Synaptic Aging and Insulin Signaling-Regulated Memory. Curr Biol. 2016;26(5):605–15. PMCID: PMC4783184 Reference Link
1.Arey R, Murphy C. Conserved regulators of cognitive aging: From worms to humans. Behav Brain Res. 2017;322(Pt B):299–310. PMCID: PMC5164975 Reference Link