1.Thokkadam A, Do T, Ran X, Brynildsen M, Yang Z, Link J. High-Throughput Screen Reveals the Structure-Activity Relationship of the Antimicrobial Lasso Peptide Ubonodin. ACS Cent Sci. 2023;9(3):540–550. PMCID: PMC10037499 Reference Link
1.Juarez R, Jiang Y, Tremblay M, Shao Q, Link J, Yang Z. LassoHTP: A High-Throughput Computational Tool for Lasso Peptide Structure Construction and Modeling. J Chem Inf Model. 2023;63(2):522–530. PMID: 36594886 Reference Link
1.Carson D, Patiño M, Elashal H, Cartagena A, Zhang Y, Whitley M, So L, Kayser-Browne A, Earl A, Bhattacharyya R, Link J. Cloacaenodin, an Antimicrobial Lasso Peptide with Activity against . ACS Infect Dis. 2023;9(1):111–121. PMCID: PMC10038104 Reference Link
1.Choi B, Elashal H, Cao L, Link J. Mechanistic Analysis of the Biosynthesis of the Aspartimidylated Graspetide Amycolimiditide. J Am Chem Soc. 2022;144(47):21628–21639. PMCID: PMC10038102 Reference Link
1.Elashal H, Koos J, Cheung-Lee W, Choi B, Cao L, Richardson M, White H, Link J. Biosynthesis and characterization of fuscimiditide, an aspartimidylated graspetide. Nat Chem. 2022;14(11):1325–1334. PMCID: PMC10078976 Reference Link
1.Do T, Thokkadam A, Leach R, Link J. Phenotype-Guided Comparative Genomics Identifies the Complete Transport Pathway of the Antimicrobial Lasso Peptide Ubonodin in . ACS Chem Biol. 2022;17(8):2332–2343. PMCID: PMC9454059 Reference Link
1.Wan X, Link J, Brynildsen M. Translational Fusion to Hmp Improves Heterologous Protein Expression. Microorganisms. 2022;10(2). PMCID: PMC8879370 Reference Link
1.Do T, Link J. Protein Engineering in Ribosomally Synthesized and Post-translationally Modified Peptides (RiPPs). Biochemistry. 2023;62(2):201–209. PMCID: PMC9454058 Reference Link
1.Schröder H, Stadlmeier M, Wühr M, Link J. The Shuttling Cascade in Lasso Peptide Benenodin-1 is Controlled by Non-Covalent Interactions. Chemistry. 2022;28(5):e202103615. PMCID: PMC8792204 Reference Link
1.Schröder H, Zhang Y, Link J. Dynamic covalent self-assembly of mechanically interlocked molecules solely made from peptides. Nat Chem. 2021;13(9):850–857. PMCID: PMC8446321 Reference Link
1.Cao L, Beiser M, Koos J, Orlova M, Elashal H, Schröder H, Link J. Cellulonodin-2 and Lihuanodin: Lasso Peptides with an Aspartimide Post-Translational Modification. J Am Chem Soc. 2021;143(30):11690–11702. PMCID: PMC9206484 Reference Link
1.Cao L, Do T, Link J. Mechanisms of action of ribosomally synthesized and posttranslationally modified peptides (RiPPs). J Ind Microbiol Biotechnol. 2021;48(3-4). PMCID: PMC8183687 Reference Link
1.Nerger B, Jaslove J, Elashal H, Mao S, Košmrlj A, Link J, Nelson C. Local accumulation of extracellular matrix regulates global morphogenetic patterning in the developing mammary gland. Curr Biol. 2021;31(9):1903–1917.e6. PMCID: PMC8119325 Reference Link
1.Baltz R, Kao K, Link J, Marsili E, Reguera G, Shao Z, Vandamme E, Jeffries T, Gonzalez R. Introduction to Special Issue on "Frontiers in Industrial Microbiology and Biotechnology 2020". J Ind Microbiol Biotechnol. 2020;47(9-10):621–622. PMCID: 7358296 Reference Link
1.Montalbán-López M, Scott T, Ramesh S, Rahman I, van Heel A, Viel J, Bandarian V, Dittmann E, Genilloud O, Goto Y, Burgos M, Hill C, Kim S, Koehnke J, Latham J, Link J, Martínez B, Nair S, Nicolet Y, Rebuffat S, Sahl H-G, Sareen D, Schmidt E, Schmitt L, Severinov K, Süssmuth R, Truman A, Wang H, Weng J-K, van Wezel G, Zhang Q, Zhong J, Piel J, Mitchell D, Kuipers O, van der Donk W. New developments in RiPP discovery, enzymology and engineering. Nat Prod Rep. 2021;38(1):130–239. PMCID: PMC7864896 Reference Link
1.Chou W, Vaikunthan M, Schröder H, Link J, Kim H, Brynildsen M. Synergy Screening Identifies a Compound That Selectively Enhances the Antibacterial Activity of Nitric Oxide. Front Bioeng Biotechnol. 2020;8:1001. PMCID: PMC7477088 Reference Link
1.Cheung-Lee W, Cao L, Link J. Pandonodin: A Proteobacterial Lasso Peptide with an Exceptionally Long C-Terminal Tail. ACS Chem Biol. 2019;14(12):2783–2792. PMCID: PMC7010350 Reference Link
1.Cheung-Lee W, Parry M, Zong C, Cartagena A, Darst S, Connell N, Russo R, Link J. Discovery of Ubonodin, an Antimicrobial Lasso Peptide Active against Members of the Burkholderia cepacia Complex. Chembiochem. 2020;21(9):1335–1340. PMCID: PMC7205569 Reference Link
1.Cheung-Lee W, Link J. Genome mining for lasso peptides: past, present, and future. J Ind Microbiol Biotechnol. 2019;46(9-10):1371–1379. PMCID: PMC6989040 Reference Link
1.Cheung-Lee W, Parry M, Cartagena A, Darst S, Link J. Discovery and structure of the antimicrobial lasso peptide citrocin. J Biol Chem. 2019;294(17):6822–6830. PMCID: PMC6497930 Reference Link
1.Piscotta F, Jeffrey P, Link J. ParST is a widespread toxin-antitoxin module that targets nucleotide metabolism. Proc Natl Acad Sci U S A. 2019;116(3):826–834. PMCID: PMC6338849 Reference Link
1.Braffman N, Piscotta F, Hauver J, Campbell E, Link J, Darst S. Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc Natl Acad Sci U S A. 2019;116(4):1273–1278. PMCID: PMC6347699 Reference Link
1.Elashal H, Cohen R, Elashal H, Zong C, Link J, Raj M. Cyclic and Lasso Peptides: Sequence Determination, Topology Analysis, and Rotaxane Formation. Angew Chem Int Ed Engl. 2018;57(21):6150–6154. PMCID: PMC6080247 Reference Link
1.Zong C, Cheung-Lee W, Elashal H, Raj M, Link J. Albusnodin: an acetylated lasso peptide from Streptomyces albus. Chem Commun (Camb). 2018;54(11):1339–1342. PMCID: PMC5835390 Reference Link
1.Zong C, Wu M, Qin J, Link J. Lasso Peptide Benenodin-1 Is a Thermally Actuated [1]Rotaxane Switch. J Am Chem Soc. 2017;139(30):10403–10409. PMCID: PMC5576865 Reference Link
1.Allen C, Chen M, Trick A, Le D, Ferguson A, Link J. Thermal Unthreading of the Lasso Peptides Astexin-2 and Astexin-3. ACS Chem Biol. 2016;11(11):3043–3051. PMCID: PMC5148663 Reference Link
1.Cheung W, Chen M, Maksimov M, Link J. Lasso Peptide Biosynthetic Protein LarB1 Binds Both Leader and Core Peptide Regions of the Precursor Protein LarA. ACS Cent Sci. 2016;2(10):702–709. PMCID: PMC5084080 Reference Link
1.Allen C, Link J. Self-Assembly of Catenanes from Lasso Peptides. J Am Chem Soc. 2016;138(43):14214–14217. PMCID: PMC5245162 Reference Link
1.Chekan J, Koos J, Zong C, Maksimov M, Link J, Nair S. Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates. J Am Chem Soc. 2016;138(50):16452–16458. PMCID: PMC5245167 Reference Link
1.Futran A, Kyin S, Shvartsman S, Link J. Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking. Proc Natl Acad Sci U S A. 2015;112(28):8590–5. PMCID: PMC4507193 Reference Link
1.Link J. Biosynthesis: Leading the way to RiPPs. Nat Chem Biol. 2015;11(8):551–2. PMCID: PMC4794250 Reference Link
1.Zong C, Maksimov M, Link J. Construction of Lasso Peptide Fusion Proteins. ACS Chem Biol. 2016;11(1):61–8. PMCID: PMC4795474 Reference Link
1.Maksimov M, Koos J, Zong C, Lisko B, Link J. Elucidating the Specificity Determinants of the AtxE2 Lasso Peptide Isopeptidase. J Biol Chem. 2015;290(52):30806–12. PMCID: PMC4692210 Reference Link
1.Arnaudo A, Link J, Garcia B. Bioorthogonal Chemistry for the Isolation and Study of Newly Synthesized Histones and Their Modifications. ACS Chem Biol. 2016;11(3):782–91. PMCID: PMC4844183 Reference Link