1.Li Z, Jin X, Wu T, Huang G, Wu K, Lei J, Pan X, Yan N. Structural Basis for Pore Blockade of the Human Cardiac Sodium Channel Na 1.5 by the Antiarrhythmic Drug Quinidine*. Angew Chem Int Ed Engl. 2021;60(20):11474–11480. PMID: 33684260 Reference Link
1.Li Z, Jin X, Wu T, Zhao X, Wang W, Lei J, Pan X, Yan N. Structure of human Na1.5 reveals the fast inactivation-related segments as a mutational hotspot for the long QT syndrome. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980460 Reference Link
1.Pan X, Li Z, Jin X, Zhao Y, Huang G, Huang X, Shen Z, Cao Y, Dong M, Lei J, Yan N. Comparative structural analysis of human Na1.1 and Na1.5 reveals mutational hotspots for sodium channelopathies. Proc Natl Acad Sci U S A. 2021;118(11). PMCID: PMC7980448 Reference Link
1.Pan X, Li Z, Huang X, Huang G, Gao S, Shen H, Liu L, Lei J, Yan N. Molecular basis for pore blockade of human Na channel Na1.2 by the μ-conotoxin KIIIA. Science. 2019;363(6433):1309–1313. PMID: 30765605 Reference Link
1.Pan X, Li Z, Zhou Q, Shen H, Wu K, Huang X, Chen J, Zhang J, Zhu X, Lei J, Xiong W, Gong H, Xiao B, Yan N. Structure of the human voltage-gated sodium channel Na1.4 in complex with β1. Science. 2018;362(6412). PMID: 30190309 Reference Link
1.Shen H, Li Z, Jiang Y, Pan X, Wu J, Cristofori-Armstrong B, Smith J, K Y Chin Y, Lei J, Zhou Q, King G, Yan N. Structural basis for the modulation of voltage-gated sodium channels by animal toxins. Science. 2018;362(6412). PMID: 30049784 Reference Link
1.Yan Z, Bai X, Yan C, Wu J, Li Z, Xie T, Peng W, Yin C, Li X, Scheres S, Shi Y, Yan N. Structure of the rabbit ryanodine receptor RyR1 at near-atomic resolution. Nature. 2015;517(7532):50–55. PMCID: PMC4338550 Reference Link
1.Wu J, Yan Z, Li Z, Yan C, Lu S, Dong M, Yan N. Structure of the voltage-gated calcium channel Cav1.1 complex. Science. 2015;350(6267):aad2395. PMID: 26680202 Reference Link
1.Bai X-C, Yan Z, Wu J, Li Z, Yan N. The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening. Cell Res. 2016;26(9):995–1006. PMCID: PMC5034110 Reference Link
1.Shen H, Zhou Q, Pan X, Li Z, Wu J, Yan N. Structure of a eukaryotic voltage-gated sodium channel at near-atomic resolution. Science. 2017;355(6328). PMID: 28183995 Reference Link
