1.Nolan E, Kang Y, Malanchi I. Mechanisms of Organ-Specific Metastasis of Breast Cancer. Cold Spring Harb Perspect Med. 2023;. PMID: 36987584 Reference Link
1.Chen Z, Kang Y. Cold snap for cancer: cold-induced brown fat thermogenesis starves tumor growth. Signal Transduct Target Ther. 2023;8(1):10. PMCID: PMC9826784 Reference Link
1.Son J, Du W, Esposito M, Shariati K, Ding H, Kang Y, Accili D. Genetic and pharmacologic inhibition of ALDH1A3 as a treatment of β-cell failure. Nat Commun. 2023;14(1):558. PMCID: PMC9895451 Reference Link
1.Bartman C, Weilandt D, Shen Y, Lee W, Han Y, TeSlaa T, Jankowski C, Samarah L, Park N, da Silva-Diz V, Aleksandrova M, Gultekin Y, Marishta A, Wang L, Yang L, Roichman A, Bhatt V, Lan T, Hu Z, Xing X, Lu W, Davidson S, Wühr M, Heiden M, Herranz D, Guo J, Kang Y, Rabinowitz J. Slow TCA flux and ATP production in primary solid tumours but not metastases. Nature. 2023;614(7947):349–357. PMID: 36725930 Reference Link
1.Shen M, Kang Y. Cancer fitness genes: emerging therapeutic targets for metastasis. Trends Cancer. 2023;9(1):69–82. PMID: 36184492 Reference Link
1.Chen H, Zhan M, Liu J, Liu Z, Shen M, Yang F, Kang Y, Yin F, Li Z. Structure-Based Design, Optimization, and Evaluation of Potent Stabilized Peptide Inhibitors Disrupting MTDH and SND1 Interaction. J Med Chem. 2022;65(18):12188–12199. PMID: 36044768 Reference Link
1.Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias J, Siebel C, Blanco M, Klein-Szanto A, Lengner C, Welm A, Kang Y, Chakrabarti R. Author Correction: Dll1+ quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2022;13(1):3927. PMCID: PMC9262875 Reference Link
1.Tang Y, Kang Y. Microbial metabolite as icebreaker for immunotherapy. Cell Metab. 2022;34(4):506–507. PMID: 35385701 Reference Link
1.Pérez-Núñez I, Rozalén C, Palomeque J, Sangrador I, Dalmau M, Comerma L, Hernández-Prat A, Casadevall D, Menendez S, Liu D, Shen M, Berenguer J, Ruiz I, Peña R, Montañés J, Albà M, Bonnin S, Ponomarenko J, Gomis R, Cejalvo J, Servitja S, Marzese D, Morey L, Voorwerk L, Arribas J, Bermejo B, Kok M, Pusztai L, Kang Y, Albanell J, Celià-Terrassa T. LCOR mediates interferon-independent tumor immunogenicity and responsiveness to immune-checkpoint blockade in triple-negative breast cancer. Nat Cancer. 2022;3(3):355–370. PMCID: 5391692 Reference Link
1.Meng J, Jiang Y-Z, Zhao S, Tao Y, Zhang T, Wang X, Zhang Y, Sun K, Yuan M, Chen J, Wei Y, Lan X, Chen M, David C, Chang Z, Guo X, Pan D, Chen M, Shao Z-M, Kang Y, Zheng H. Tumor-derived Jagged1 promotes cancer progression through immune evasion. Cell Rep. 2022;38(10):110492. PMID: 35263601 Reference Link
1.Shen M, Wei Y, Kim H, Wan L, Jiang Y-Z, Hang X, Raba M, Remiszewski S, Rowicki M, Wu C-G, Wu S, Zhang L, Lu X, Yuan M, Smith H, Zheng A, Bertino J, Jin J, Xing Y, Shao Z-M, Kang Y. Small-molecule inhibitors that disrupt the MTDH-SND1 complex suppress breast cancer progression and metastasis. Nat Cancer. 2022;3(1):43–59. PMCID: PMC8818087 Reference Link
1.Shen M, Smith H, Wei Y, Jiang Y-Z, Zhao S, Wang N, Rowicki M, Tang Y, Hang X, Wu S, Wan L, Shao Z-M, Kang Y. Pharmacological disruption of the MTDH-SND1 complex enhances tumor antigen presentation and synergizes with anti-PD-1 therapy in metastatic breast cancer. Nat Cancer. 2022;3(1):60–74. PMCID: PMC8818088 Reference Link
1.Fang C, Kang Y. E-Cadherin: Context-Dependent Functions of a Quintessential Epithelial Marker in Metastasis. Cancer Res. 2021;81(23):5800–5802. PMID: 34853039 Reference Link
1.Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford H, Fuxe J, de Herreros A, Goodall G, Hadjantonakis A-K, Huang R, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore G, Mani S, Massagué J, Mayor R, McClay D, Mostov K, Newgreen D, Nieto A, Puisieux A, Runyan R, Savagner P, Stanger B, Stemmler M, Takahashi Y, Takeichi M, Theveneau E, Thiery J, Thompson E, Weinberg R, Williams E, Xing J, Zhou B, Sheng G, EMT International Association (TEMTIA). Author Correction: Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2021;22(12):834. PMCID: PMC8604719 Reference Link
1.Kumar S, Nandi A, Singh S, Regulapati R, Li N, Tobias J, Siebel C, Blanco M, Klein-Szanto A, Lengner C, Welm A, Kang Y, Chakrabarti R. Dll1 quiescent tumor stem cells drive chemoresistance in breast cancer through NF-κB survival pathway. Nat Commun. 2021;12(1):432. PMCID: PMC7813834 Reference Link
1.Kang Y, Kuperwasser C. Evolving barcodes shed light into evolving metastases. Dev Cell. 2021;56(8):1077–1079. PMID: 33878297 Reference Link
1.Lee E, Kang Y. Lineage tracing reveals metastatic dynamics. Cancer Cell. 2021;39(8):1050–1052. PMID: 34171265 Reference Link
1.Yang M, Hu X, Bao W, Zhang X, Lin Y, Stanton S, Haffty B, Hu W, Kang Y, Wei S, Zhang L. Changing trends and disparities in 5-year overall survival of women with invasive breast cancer in the United States, 1975-2015. Am J Cancer Res. 2021;11(6):3201–3211. PMCID: PMC8263668 Reference Link
1.Esposito M, Ganesan S, Kang Y. Emerging strategies for treating metastasis. Nat Cancer. 2021;2(3):258–270. PMCID: PMC8064405 Reference Link
1.Chen F, Han Y, Kang Y. Bone marrow niches in the regulation of bone metastasis. Br J Cancer. 2021;124(12):1912–1920. PMCID: PMC8184962 Reference Link
1.Esposito M, Fang C, Cook K, Park N, Wei Y, Spadazzi C, Bracha D, Gunaratna R, Laevsky G, DeCoste C, Slabodkin H, Brangwynne C, Cristea I, Kang Y. TGF-β-induced DACT1 biomolecular condensates repress Wnt signalling to promote bone metastasis. Nat Cell Biol. 2021;23(3):257–267. PMCID: PMC7970447 Reference Link
1.Shen M, Kang Y. Stresses in the metastatic cascade: molecular mechanisms and therapeutic opportunities. Genes Dev. 2020;34(23-24):1577–1598. PMCID: PMC7706714 Reference Link
1.Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin J, Jaschinski F, Zhou T, Klar R, Kang Y. Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis. Cancer Res. 2021;81(4):1014–1025. PMCID: PMC8026491 Reference Link
1.Spadazzi C, Mercatali L, Esposito M, Wei Y, Liverani C, De Vita A, Miserocchi G, Carretta E, Zanoni M, Cocchi C, Bongiovanni A, Recine F, Kang Y, Ibrahim T. Trefoil factor-1 upregulation in estrogen-receptor positive breast cancer correlates with an increased risk of bone metastasis. Bone. 2021;144:115775. PMID: 33249323 Reference Link
1.Fang C, Kang Y. Cellular plasticity in bone metastasis. Bone. 2022;158:115693. PMCID: PMC8046848 Reference Link
1.Li W, Shen M, Jiang Y-Z, Zhang R, Zheng H, Wei Y, Shao Z-M, Kang Y. Deubiquitinase USP20 promotes breast cancer metastasis by stabilizing SNAI2. Genes Dev. 2020;34(19-20):1310–1315. PMCID: PMC7528704 Reference Link
1.Fan H, Wang X, Li W, Shen M, Wei Y, Zheng H, Kang Y. ASB13 inhibits breast cancer metastasis through promoting SNAI2 degradation and relieving its transcriptional repression of YAP. Genes Dev. 2020;34(19-20):1359–1372. PMCID: PMC7528707 Reference Link
1.Song K, Cai X, Dong Y, Wu H, Wei Y, Shankavaram U, Cui K, Lee Y, Zhu B, Bhattacharjee S, Wang B, Zhang K, Wen A, Wong S, Yu L, Xia L, Welm A, Bielenberg D, Camphausen K, Kang Y, Chen H. Epsins 1 and 2 promote NEMO linear ubiquitination via LUBAC to drive breast cancer development. J Clin Invest. 2021;131(1). PMCID: PMC7773373 Reference Link
1.Vrla G, Esposito M, Zhang C, Kang Y, Seyedsayamdost M, Gitai Z. Cytotoxic alkyl-quinolones mediate surface-induced virulence in Pseudomonas aeruginosa. PLoS Pathog. 2020;16(9):e1008867. PMCID: PMC7515202 Reference Link
1.Pham K, Huynh D, Le L, Delitto D, Yang L, Huang J, Kang Y, Steinberg M, Li J, Zhang L, Liu D, Tang M-S, Liu C, Wang H. E-cigarette promotes breast carcinoma progression and lung metastasis: Macrophage-tumor cells crosstalk and the role of CCL5 and VCAM-1. Cancer Lett. 2020;491:132–145. PMCID: PMC9703643 Reference Link
1.Hoshino A, Kim H, Bojmar L, Gyan K, Cioffi M, Hernandez J, Zambirinis C, Rodrigues G, Molina H, Heissel S, Mark M, Steiner L, Benito-Martin A, Lucotti S, Di Giannatale A, Offer K, Nakajima M, Williams C, Nogués L, Vatter F, Hashimoto A, Davies A, Freitas D, Kenific C, Ararso Y, Buehring W, Lauritzen P, Ogitani Y, Sugiura K, Takahashi N, Alečković M, Bailey K, Jolissant J, Wang H, Harris A, Schaeffer M, García-Santos G, Posner Z, Balachandran V, Khakoo Y, Raju P, Scherz A, Sagi I, Scherz-Shouval R, Yarden Y, Oren M, Malladi M, Petriccione M, De Braganca K, Donzelli M, Fischer C, Vitolano S, Wright G, Ganshaw L, Marrano M, Ahmed A, DeStefano J, Danzer E, Roehrl M, Lacayo N, Vincent T, Weiser M, Brady M, Meyers P, Wexler L, Ambati S, Chou A, Slotkin E, Modak S, Roberts S, Basu E, Diolaiti D, Krantz B, Cardoso F, Simpson A, Berger M, Rudin C, Simeone D, Jain M, Ghajar C, Batra S, Stanger B, Bui J, Brown K, Rajasekhar V, Healey J, de Sousa M, Kramer K, Sheth S, Baisch J, Pascual V, Heaton T, La Quaglia M, Pisapia D, Schwartz R, Zhang H, Liu Y, Shukla A, Blavier L, DeClerck Y, LaBarge M, Bissell M, Caffrey T, Grandgenett P, Hollingsworth M, Bromberg J, Costa-Silva B, Peinado H, Kang Y, Garcia B, O’Reilly E, Kelsen D, Trippett T, Jones D, Matei I, Jarnagin W, Lyden D. Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers. Cell. 2020;182(4):1044–1061.e18. PMCID: PMC7522766 Reference Link
1.Aiello-Couzo N, Kang Y. A bridge between melanoma cell states. Nat Cell Biol. 2020;22(8):913–914. PMID: 32753670 Reference Link
1.Ghergurovich J, Esposito M, Chen Z, Wang J, Bhatt V, Lan T, White E, Kang Y, Guo J, Rabinowitz J. Glucose-6-Phosphate Dehydrogenase Is Not Essential for K-Ras-Driven Tumor Growth or Metastasis. Cancer Res. 2020;80(18):3820–3829. PMCID: PMC7501231 Reference Link
1.Yang J, Antin P, Berx G, Blanpain C, Brabletz T, Bronner M, Campbell K, Cano A, Casanova J, Christofori G, Dedhar S, Derynck R, Ford H, Fuxe J, de Herreros A, Goodall G, Hadjantonakis A-K, Huang R, Kalcheim C, Kalluri R, Kang Y, Khew-Goodall Y, Levine H, Liu J, Longmore G, Mani S, Massagué J, Mayor R, McClay D, Mostov K, Newgreen D, Nieto A, Puisieux A, Runyan R, Savagner P, Stanger B, Stemmler M, Takahashi Y, Takeichi M, Theveneau E, Thiery J, Thompson E, Weinberg R, Williams E, Xing J, Zhou B, Sheng G, EMT International Association (TEMTIA). Guidelines and definitions for research on epithelial-mesenchymal transition. Nat Rev Mol Cell Biol. 2020;21(6):341–352. PMCID: PMC7250738 Reference Link
1.Shen M, Kang Y. Role Reversal: A Pro-metastatic Function of E-Cadherin. Dev Cell. 2019;51(4):417–419. PMID: 31743661 Reference Link
1.Liverani C, De Vita A, Minardi S, Kang Y, Mercatali L, Amadori D, Bongiovanni A, La Manna F, Ibrahim T, Tasciotti E. A biomimetic 3D model of hypoxia-driven cancer progression. Sci Rep. 2019;9(1):12263. PMCID: PMC6706452 Reference Link
1.Lu W, Kang Y. Epithelial-Mesenchymal Plasticity in Cancer Progression and Metastasis. Dev Cell. 2019;49(3):361–374. PMCID: PMC6506183 Reference Link
1.Zijlstra A, Von Lersner A, Yu D, Borrello L, Oudin M, Kang Y, Sahai E, Fingleton B, Stein U, Cox T, Price J, Kato Y, Welm A, Aguirre-Ghiso J, Board Members of the Metastasis Research Society. The importance of developing therapies targeting the biological spectrum of metastatic disease. Clin Exp Metastasis. 2019;36(4):305–309. PMCID: PMC8794535 Reference Link
1.Celià-Terrassa T, Bastian C, Liu D, Ell B, Aiello N, Wei Y, Zamalloa J, Blanco A, Hang X, Kunisky D, Li W, Williams E, Rabitz H, Kang Y. Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability. Nat Commun. 2018;9(1):5005. PMCID: PMC6258667 Reference Link
1.Monsivais D, Peng J, Kang Y, Matzuk M. Activin-like kinase 5 (ALK5) inactivation in the mouse uterus results in metastatic endometrial carcinoma. Proc Natl Acad Sci U S A. 2019;116(9):3883–3892. PMCID: PMC6397539 Reference Link
1.Celià-Terrassa T, Bastian C, Liu D, Ell B, Aiello N, Wei Y, Zamalloa J, Blanco A, Hang X, Kunisky D, Li W, Williams E, Rabitz H, Kang Y. Author Correction: Hysteresis control of epithelial-mesenchymal transition dynamics conveys a distinct program with enhanced metastatic ability. Nat Commun. 2019;10(1):527. PMCID: PMC6349917 Reference Link
1.Aiello N, Kang Y. Context-dependent EMT programs in cancer metastasis. J Exp Med. 2019;216(5):1016–1026. PMCID: PMC6504222 Reference Link
1.Esposito M, Mondal N, Greco T, Wei Y, Spadazzi C, Lin S-C, Zheng H, Cheung C, Magnani J, Lin S-H, Cristea I, Sackstein R, Kang Y. Bone vascular niche E-selectin induces mesenchymal-epithelial transition and Wnt activation in cancer cells to promote bone metastasis. Nat Cell Biol. 2019;21(5):627–639. PMCID: PMC6556210 Reference Link
1.Zhang H, Brown R, Wei Y, Zhao P, Liu S, Liu X, Deng Y, Hu X, Zhang J, Gao X, Kang Y, Mercurio A, Goel H, Cheng C. CD44 splice isoform switching determines breast cancer stem cell state. Genes Dev. 2019;33(3-4):166–179. PMCID: PMC6362815 Reference Link
1.Lu S, Han Z, Hung M-C, Xu J, Xu Y, Zheng P, Zheng Z-M, Zou L, Li Z, Zheng L, Kang Y, Yang Y, He L, Liao C, Yu H, Yue Z, Liu S-L, Zheng H. Racial profiling harms science. Science. 2019;363(6433):1290–1292. PMID: 30898924 Reference Link
1.Zhuo W, Liu Y, Li S, Guo D, Sun Q, Jin J, Rao X, Li M, Sun M, Jiang M, Xu Y, Teng L, Jin Y, Si J, Liu W, Kang Y, Zhou T. Long Noncoding RNA GMAN, Up-regulated in Gastric Cancer Tissues, Is Associated With Metastasis in Patients and Promotes Translation of Ephrin A1 by Competitively Binding GMAN-AS. Gastroenterology. 2019;156(3):676–691.e11. PMID: 30445010 Reference Link
1.Shen M, Jiang Y-Z, Wei Y, Ell B, Sheng X, Esposito M, Kang J, Hang X, Zheng H, Rowicki M, Zhang L, Shih W, Celià-Terrassa T, Liu Y, Cristea I, Shao Z-M, Kang Y. Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling. Cancer Cell. 2019;35(1):64–80.e7. PMID: 30612941 Reference Link
1.Shen M, Kang Y. Complex interplay between tumor microenvironment and cancer therapy. Front Med. 2018;12(4):426–439. PMID: 30097962 Reference Link
1.Shen M, Kang Y. pSTAT3 Reactive Astrocytes Promote Brain Metastasis. Trends Mol Med. 2018;24(9):733–735. PMID: 30029985 Reference Link
1.Celià-Terrassa T, Kang Y. Metastatic niche functions and therapeutic opportunities. Nat Cell Biol. 2018;20(8):868–877. PMCID: 4161226 Reference Link